| SRN1 and SRN2 |
induce |
cell death |
Nicotiana benthamiana |
| cell death induction through the GR-LhG4 system |
can be efficiently induced |
|
Arabidopsis thaliana |
| VmSpm1 |
is unable to inhibit |
INF1-induced cell death |
|
| tapetal cells in Osalkbh5 mutants after Stage 10 |
exhibit |
delayed degeneration and irregular morphology |
Oryza sativa |
| reactive oxygen species (ROS) |
plays role in |
cell death |
|
| binding protein (BIP, BIP2, AT5G42020) |
can function as |
negative modulator of programmed cell death (PCD) events |
|
| PCD in separation layer |
starts at early stage 17 in |
wild type and mutants |
Arabidopsis thaliana |
| (ATBI-1, ATBI1, BI-1, BI1, AT5G47120) |
regulates |
cell death |
Arabidopsis thaliana; Nicotiana benthamiana |
| VmSpm1 |
is shown to inhibit |
Bax-induced cell death |
|
| S8 domain of VmSpm1 |
when co-infiltrated with BAX, can effectively |
suppress plant PCD |
|
| WHY proteins |
have been assigned roles in |
cell death regulation |
|
| reduction of transmembrane potential and change in permeability of mitochondrial membranes |
leads to |
release of cytochrome c from the intermembrane space to the cytosol |
Hordeum vulgare |
| homologous protein of VmSpm1 in Ustilago virens |
suppresses |
plant PCD |
Ustilago virens |
| transient expression of XBAT35.1 |
did not trigger |
cell death in tobacco leaves |
Nicotiana tabacum |
| VmSpm1 |
does not inhibit |
INF1-induced cell death |
Nicotiana benthamiana |
| arabinogalactan proteins |
have been implicated in |
cell death |
|
| (ACD6, DEG16, AT4G14400) |
is key to regulating |
plant cell death in response to pathogen attack |
Arabidopsis thaliana |
| ultrastructural cell-death symptoms |
found on day 10 of |
dark-induced leaf senescence (DILS) |
Hordeum vulgare |
| onset of TUNEL signals |
is delayed in |
(AtGH9B18, CEL6, GH9B18, AT4G39010) and (AtMAN7, MAN7, AT5G66460) mutants |
Arabidopsis thaliana |
| (BIP, BIP2, AT5G42020) overexpression |
further stimulates |
induction of NRP-mediated cell death signaling |
Glycine max |
| cell death induced by Nilaparvata lugens mucin-like protein (NlMLP) |
is suppressed by |
antiapoptotic protein Bcl-xl |
Nicotiana benthamiana |
| Nilaparvata lugens mucin-like protein (NlMLP) expression |
triggered |
cell death in Nicotiana benthamiana leaves |
Nicotiana benthamiana |
| GSLA |
reported |
distinctive functional category of PCD and hypersensitivity response |
Arabidopsis thaliana |
| (ANAC012, AtSND1, NAC012, NST3, SND1, AT1G32770) |
directly activates expression of |
cysteine protease (XCP2, AT1G20850) |
Arabidopsis thaliana |
| secondary wall NACs (SWNs) |
regulate |
programmed cell death |
|
| (ZED1, AT3G57750) I24E mutation |
greatly reduced |
ZAR1-mediated cell death |
Arabidopsis thaliana |
| (ZAR1, AT3G50950) V544E mutation |
markedly reduced |
HopZ1a-induced cell death |
Arabidopsis thaliana |
| caspase-like activity |
is pan-marker of |
plant PCD |
|
| RESPIRATORY BURST OXIDASE HOMOLOG 1 (RBOH1)-mediated reactive oxygen species (ROS) |
triggers |
programmed cell death (PCD) |
Solanum lycopersicum |
| main-2 mutant seedlings |
showed individual dead cells in only about 50% of |
seedlings |
Arabidopsis thaliana |
| genes participating in cell death |
includes |
(AtMC3, AtMCP1a, MC3, MCP1a, AT5G64240) and (CHS4, LSD1, AT4G20380) |
Solanum tuberosum |
| ABA hypersensitivity phenotype |
is closely related to |
PCD pathway |
Arabidopsis thaliana |
| interfascicular fibers of (ATGRP8, CCR1, GR-RBP8, GRP8, RBGA6, AT4G39260) -6 and -6 ProSNBE plants |
still contain |
cellular contents |
Arabidopsis thaliana |
| advanced dark-induced leaf senescence (DILS) |
involves |
nDNA fragmentation |
Hordeum vulgare |
| cell death |
was concomitant with |
induced expression of senescence and autophagy-related and vacuolar-processing genes |
Hordeum vulgare |
| (ATMC8, AtMCP2e, MC8, MCP2e, AT1G16420) and (AtMC9, AtMCP2f, MC9, MCP2f, AT5G04200) |
are likely involved in |
programmed cell death process |
|
| elevated endoplasmic reticulum stress at high Tunicamycin (Tm) concentration |
is associated with induction of |
programmed cell death |
Arabidopsis thaliana |
| PCD |
is synergistically induced by |
high light and high Tm concentration that triggered both UPR arms |
Arabidopsis thaliana |
| cytochrome c (Cc) |
inhibits |
histone chaperone function of (NRP, NRP1, AT5G42050) |
Arabidopsis thaliana |
| cell death process induced by Nilaparvata lugens mucin-like protein (NlMLP) |
is dependent on |
calcium ion (Ca2+) influx |
Nicotiana benthamiana |
| internucleosomal fragmentation of DNA (nDNA) |
has been considered as an indicator characteristic of |
programmed cell death (PCD) progression |
|
| comet assay data |
suggests |
finer DNA degradation on day 3 and PCD on days 7 and 10 in barley DILS |
Hordeum vulgare |
| cell death pathway components |
include |
N-rich protein B (NRP-B) |
Glycine max |
| LSD transcription factors |
act as |
negative regulators of programmed cell death |
Oryza sativa |
| (XCP1, AT4G35350) promoter |
drives expression of |
(XCP1, AT4G35350) |
Arabidopsis thaliana |
| Col-0 wild type |
showed strong TUNEL signals at |
4 and 5 d after anthesis in separation layer |
Arabidopsis thaliana |
| cel6-1, cel6-2, man7-1, and man7-3 mutants |
showed strong TUNEL signals only at |
5 d after anthesis in separation layer |
Arabidopsis thaliana |
| suppression of PCD |
leads to |
aberrant degeneration of aleurone cells |
Arabidopsis thaliana |
| GSLA |
can identify |
PCD and hypersensitivity response processes |
Arabidopsis thaliana |
| second, terminal phase of stress-induced leaf senescence |
is characterized by |
progression into programmed cell death (PCD) |
Hordeum vulgare |
| activated vacuolar proteins |
initiate |
proteolytic cascade in plant programmed cell death (PCD) |
|
| TUNEL assay |
detected |
nuclear DNA fragmentation in separation layer |
Arabidopsis thaliana |
| beyond day 7 of dark-induced leaf senescence (DILS) |
nucleus and mitochondria that were otherwise stable until this point became susceptible to |
degradation |
Hordeum vulgare |
| interfascicular fibers of (ATGRP8, CCR1, GR-RBP8, GRP8, RBGA6, AT4G39260) -6 and -6 ProSNBE plants |
indicate |
delay in programmed cell death |
Arabidopsis thaliana |
| degradation of nucleus and mitochondria beyond day 7 of DILS |
causing |
irreversible decline |
Hordeum vulgare |
| NRP-mediated signaling pathway |
may participate in |
execution of hypersensitive response (HR) programmed cell death (PCD) |
Glycine max |
| Nilaparvata lugens mucin-like protein (NlMLP) |
triggers |
cell death |
|
| (ANAC012, AtSND1, NAC012, NST3, SND1, AT1G32770) |
directly activates expression of |
metacaspase (ATMC8, AtMCP2e, MC8, MCP2e, AT1G16420) |
Arabidopsis thaliana |
| SWNs |
regulate |
programmed cell death |
|
| (ANAC012, AtSND1, NAC012, NST3, SND1, AT1G32770) and (ANAC030, VND7, AT1G71930) target genes |
are associated with |
programmed cell death |
Arabidopsis thaliana |
| jasmonic acid (JA) accumulation under excessive light |
is associated with the induction of |
gamma-vacuolar processing enzyme (γ-VPE) |
|
| ER stress-induced NRP-mediated PCD |
was common to |
many stress signalling pathways and was salicylate dependent |
Arabidopsis thaliana |
| cells in the center of lesions |
in the final stages of |
cell death process |
Solanum tuberosum |
| binding protein (BIP, BIP2, AT5G42020) |
attenuates |
endoplasmic reticulum-induced cell death |
|
| cell death-associated gene markers GmNAC1 and GmCystP |
are efficiently induced by |
SA treatment |
Glycine max |
| (ANAC030, VND7, AT1G71930) |
directly activates expression of |
protease-associated domain-containing vacuolar sorting receptor |
Arabidopsis thaliana |
| LaCl3 |
only partially blocked |
deleterious effects during (ZAR1, AT3G50950) activation |
Arabidopsis thaliana |
| (ZED1, AT3G57750) G29E mutation |
greatly reduced |
ZAR1-mediated cell death |
Arabidopsis thaliana |
| tunicamycin pretreatment under excessive light |
leads to development of |
leaf cell death |
Arabidopsis thaliana |
| (BIP, BIP2, AT5G42020) overexpression under developmental and abiotic stress conditions |
leads to attenuation of |
NRP-mediated cell death |
Glycine max |
| loss of function of (MAIL1, AT2G25010) |
leads to |
cell death of meristem cells |
Arabidopsis thaliana |
| mutants with defects in DNA replication |
display |
spontaneous cell death in the RAM |
Arabidopsis thaliana |
| cell death pathway components |
include |
vacuolar processing enzyme (VPE) homologs |
Glycine max |
| (BIP, BIP2, AT5G42020) |
can positively modulate |
programmed cell death (PCD) events |
Glycine max |
| (ANAC012, AtSND1, NAC012, NST3, SND1, AT1G32770) |
directly activates expression of |
bifunctional nuclease (BFN1, ENDO1, AT1G11190) |
Arabidopsis thaliana |
| (ANAC012, AtSND1, NAC012, NST3, SND1, AT1G32770) |
directly activates expression of |
metacaspase (AtMC9, AtMCP2f, MC9, MCP2f, AT5G04200) |
Arabidopsis thaliana |
| high elicitor concentrations |
induces |
cell death |
|
| artificial shifts in cytoplasmic pH |
does not induce |
cell death |
|
| GmNAC81 and GmNAC30 |
bind to promoter of |
VPE involved in PCD |
Glycine max |
| (ANAC030, VND7, AT1G71930) |
directly regulate expression of |
genes involved in programmed cell death |
|
| (XSP1, AT4G00230) |
is |
programmed cell death-related hydrolase |
|
| (ANAC030, VND7, AT1G71930) |
directly activates expression of |
metacaspase (AtMC9, AtMCP2f, MC9, MCP2f, AT5G04200) |
Arabidopsis thaliana |
| (ANAC030, VND7, AT1G71930) |
directly activates expression of |
serine carboxypeptidase family proteins |
Arabidopsis thaliana |
| NRP-overexpressing soybean lines |
strongly induce |
GmNAC81 |
Glycine max |
| this work |
establishes |
common biochemical features between human and plant PCD |
Arabidopsis thaliana; human |
| mitogen-activated kinases |
are critical for |
some types of programmed cell death |
|
| Monstera |
uses |
programmed cell death or abscission for finalizing leaf shapes |
Monstera |
| dying plant cells |
have to prepare their own demise in |
cell-autonomous fashion |
|
| autoactivation of cytoplasmic immune receptor proteins |
can trigger |
pPCD phenotypes |
|
| (ATBAK1, ATSERK3, BAK1, ELG, RKS10, SERK3, AT4G33430) |
associates with SOBIR to mediate |
pPCD |
|
| global induction of unfolded protein response sensors |
correlates with |
occurrence of cell death |
Arabidopsis thaliana |
| (EZA1, SDG10, SWN, AT4G02020) proteins |
directly regulate expression of |
programmed cell death-related genes |
|
| reactive oxygen species (ROS) |
are essential signals for |
hypersensitive response in pathogenic infection-induced PCD |
|
| (ATSIG6, SIG6, SIGF, SOLDAT8, AT2G36990) and (EMB93, SOLDAT10, AT2G03050) mutants |
suppress |
1O2-induced cell death in flu mutant |
Arabidopsis thaliana |
| GmNAC81 |
interacts with |
GmNAC30 |
Glycine max |
| caspase-like activity |
acts downstream of |
reactive carbonyl species (RCS) |
|
| strong ER stress |
leads to |
sensitive phenotype and activation of PCD in strong light |
Arabidopsis thaliana |
| marker genes of PCD |
were induced by high light in |
Tm-treated plants |
Arabidopsis thaliana |
| (PP7L, AT5G10900) mutant lines |
show |
cell death in the RAM |
Arabidopsis thaliana |
| newly synthesized unusual fatty acids (UFAs) |
can result in |
cell death |
|
| cytochrome c (Cc) |
is released from |
mitochondria |
yeast; plants; Drosophila; humans |
| cytochrome c (Cc) |
may trigger or modulate |
saspase activity |
plants |
| caspase-like activity |
mediates |
excessive light-induced PCD |
|
| salicylic acid |
is instrumental in |
high light-induced cell death |
Arabidopsis thaliana |
| (AtMC6, AtMCP2c, MC6, MCP2c, AT1G79320) |
is |
one of the PCD-related genes |
Arabidopsis thaliana |
| synergid cell with higher cytosolic Calcium concentration (DSY) |
degenerates |
cell death |
Arabidopsis thaliana |
| mcII-Pa |
promotes |
autophagy |
Picea abies |
| celastrol |
promotes |
apoptosis |
|
| (ANAC030, VND7, AT1G71930) |
directly activates expression of |
non-transcription factor genes involved in programmed cell death |
Arabidopsis thaliana |
| (ANAC012, AtSND1, NAC012, NST3, SND1, AT1G32770) |
directly activates expression of |
serine carboxypeptidase family proteins |
Arabidopsis thaliana |
| Aspartyl Protease Family Protein |
is |
direct target of SWNs |
|
| (EZA1, SDG10, SWN, AT4G02020) master switches and their downstream transcription factors |
directly regulate |
target genes involved in programmed cell death |
|
| jasmonic acids (JAs) |
mediate |
programmed cell death under abiotic stress conditions |
|
| mechanisms underlying Tunicamycin (Tm)-induced programmed cell death and high light-induced programmed cell death |
do not fully overlap |
|
Arabidopsis thaliana |
| loss of CRUMPLED LEAF (CAA33, CRL, AT5G51020) |
leads to |
localized foliar cell death |
Arabidopsis thaliana |
| dihydrosphingosine (d18:0, (DHS, EDA22, AT5G05920) ) |
induces |
apoptotic-like response |
Nicotiana tabacum |
| plants |
lack |
Apaf-1 homologue |
plants |
| genes encoding KTI or homologues |
have been suggested to be involved in |
regulation of PCD |
|
| AT1-β/22 cell population treated with UV-C (50 J m −2) |
showed |
occurrence of PCD |
Daucus carota L. |
| (ANAC030, VND7, AT1G71930) |
directly activates expression of |
bifunctional nuclease (BFN1, ENDO1, AT1G11190) |
Arabidopsis thaliana |
| transient expression of (LecRK-IX.2, AT5G65600) |
induces |
cell death |
Nicotiana benthamiana |
| transition between cells in final stages of cell death and normal cells |
limited to |
narrow layer of cells of different types |
Solanum tuberosum |
| Tyrosine phosphatase (Solyc01g107750.3) |
is significantly downregulated in |
CR-slida |
Solanum lycopersicum |
| cytochrome c (Cc) |
may trigger or modulate |
phytaspase activity |
plants |
| Col-0 protoplasts co-transfected with (ZAR1, AT3G50950) (RKS1, ZRK1, AT3G57710) (APK2A, Kin1, PBL2, AT1G14370) and AvrAC |
resulted in |
complete cell death |
Arabidopsis thaliana |
| loss of function of MAIN |
leads to |
cell death of meristem cells |
Arabidopsis thaliana |
| programmed cell death (PCD) |
is essential for |
development and homeostasis of multicellular organisms |
|
| ER-mediated PCD |
involves regulation of |
pro- or anti-death members of Bcl-2 family |
|
| (anac089, FSQ6, NAC089, NTL14, AT5G22290) |
controls |
(AMC6, ATMC5, ATMCP2b, MC5, MCP2b, AT1G79330) |
Arabidopsis thaliana |
| (ANAC030, VND7, AT1G71930) |
directly activates |
(BFN1, ENDO1, AT1G11190) |
|
| (ANAC030, VND7, AT1G71930) |
directly activates |
(XCP1, AT4G35350) |
|
| ANAC089ΔTM overexpression |
induced |
HR-like cell death symptoms |
Nicotiana tabacum |
| exogenous ATP |
attenuates |
FB1-induced cell death |
Arabidopsis thaliana |
| lace plant |
uses |
programmed cell death for finalizing leaf shapes |
Aponogeton madagascariensis |
| autophagy promoted by mcII-Pa |
prevents the switch to |
necrotic form of cell death |
Picea abies |
| mutants with impaired function of histone chaperone complexes |
display |
spontaneous cell death in the RAM |
Arabidopsis thaliana |
| precocious or delayed PCD |
can have detrimental consequences for |
plant development |
|
| (anac089, FSQ6, NAC089, NTL14, AT5G22290) |
controls |
(ATBAG6, BAG6, AT2G46240) |
Arabidopsis thaliana |
| (AKIN10, KIN10, SnRK1, SnRK1α1, SNRK1.1, AT3G01090) |
was activated to |
induce premature PCD |
Zea mays |
| mutants lacking components of the mediator complex |
display |
spontaneous cell death in the RAM |
Arabidopsis thaliana |
| multiple cysteine residues predicted to form disulfide bonds |
are required for |
CRK28-mediated cell death |
Arabidopsis thaliana |
| cell death pathway components |
include |
GmNAC81 |
Glycine max |
| loss of EARLY LESION LEAF 1 (ELL1, FK, HYD2, AT3G52940) function |
induces |
lesion formation |
Oryza sativa |
| developmental PCD |
is followed by |
cell corpse clearance |
|
| plant autophagy |
participates in regulation of |
programmed cell death (PCD) |
|
| lateral root cap (LRC) cells |
may share |
same dRCA module as xylem cells |
Arabidopsis thaliana |
| (DAD1, AT2G44810) loss-of-function mutations in Arabidopsis |
enhanced |
extent of cell death under high light stress |
Arabidopsis thaliana |
| (AKIN10, KIN10, SnRK1, SnRK1α1, SNRK1.1, AT3G01090) (Snf1-related protein kinase 1) |
links to |
senescence |
|
| VASCULAR-RELATED NAC-DOMAIN (VND) 6 and (ANAC030, VND7, AT1G71930) |
directly upregulate |
XYLEM CYSTEINE PROTEASE (XCP) 2 |
|
| ET |
can apparently both promote and inhibit |
programmed cell death (PCD) |
Arabidopsis thaliana |
| serinyl Asp-specific proteases (saspases) |
participate in |
PCD of plants |
|
| DNA fragmentation in dark-grown heat-treated cells |
may be more extensive in |
DNA fragmentation in light-grown heat-treated cells |
Arabidopsis thaliana |
| caspase family of cysteine proteases |
execute |
PCD in animals |
animals |
| diphenyleniodonium (DPI) |
blocking ROS production using |
DHS-induced cell death |
Nicotiana tabacum |
| CR-slida tapetal cells |
show weak TUNEL signal at |
microspore stage |
Solanum lycopersicum |
| CR-slida microspores |
show strong TUNEL signal at |
microspore stage |
Solanum lycopersicum |
| metacaspase 1 (MC) |
is |
one of the PCD-related genes |
Arabidopsis thaliana |
| trypan blue staining |
detects |
cell death |
Oryza sativa |
| comprehensive study of lesion-mimic mutants (LMMs) |
explains |
molecular mechanisms and signaling pathways governing programmed cell death (PCD) occurrence |
|
| autophagy promoted by mcII-Pa |
is necessary for |
controlled PCD execution |
Picea abies |
| oxalic acid deficiency in S. sclerotiorum |
induces |
autophagy-mediated cell death |
Sclerotinia sclerotiorum |
| cytochrome c (Cc) |
is released into |
cytoplasm |
yeast; plants; Drosophila; humans |
| BnaNAC60 |
modulates |
cell death |
Brassica napus |
| facultative non-cell autonomous forms of dPCD |
possibly more closely related to |
forms of pPCD |
|
| lytic enzymes |
is activated or released from safe storage compartments to |
degrade cellular components |
|
| lysigenous aerenchyma |
forms by |
cell degradation |
|
| changes in cell walls |
are detected at |
onset of programmed cell death (PCD) |
Zea mays |
| cyclic nucleotide-gated ion channels (CNGC) |
have role in |
cell death |
|
| lysigenous aerenchyma |
forms in |
roots and shoots of wetland species |
|
| predicted metacaspase protein of 418 amino acids |
contained |
caspase domain structures |
Pinus sylvestris |
| chloroplast alterations |
indicates |
cell death induction |
Chlorella saccharophila |
| elicitor(s) in protein extracts from HS-treated cells |
induces |
death in cells |
Chlamydomonas saccharophila |
| (BFN1, ENDO1, AT1G11190) mutant |
exhibits |
non-degraded nuclear remnants at the root surface |
Arabidopsis thaliana |
| nitric oxide (NO) |
is |
potential pPCD trigger |
|
| (ATCAO, CAO, CH1, AT1G44446) mutant |
exhibits increased expression of |
(anac089, FSQ6, NAC089, NTL14, AT5G22290) |
Arabidopsis thaliana |
| cell death in pp7l-1 mutant |
exhibited |
numerous cells across mitotic zone of root apical meristem (RAM) |
Arabidopsis thaliana |
| autophagy |
can promote or restrict |
programmed cell death (PCD) |
|
| Metacaspases (MCs) |
do not possess |
caspase-like activity |
|
| membrane-associated immune receptor-like kinases (RLKs) |
can regulate |
cell death |
|
| (ATEDS1, EDS1, AT3G48090) family |
is required for |
cell death by conserved TIR-only proteins |
|
| (ELL1, FK, HYD2, AT3G52940) mutant leaves |
show |
numerous TUNEL-positive nuclei |
|
| (AtTN10, TIR, TN10, AT1G72930) of SARM1 |
induce |
EDS1-independent necrosis |
Nicotiana benthamiana |
| ultrastructural markers of PCD in vacuolate microspores |
included |
rupture of the tonoplast |
Brassica napus |
| developmentally regulated programmed cell death (PCD) |
occurs at predictable time and location, and is induced by |
internal factors |
|
| lysigenous aerenchyma |
is known to form as consequence of |
programmed cell death (PCD) |
|
| IPG-1 |
implicate |
involvement in PCD process in plant cells |
Brassica napus |
| DNA fragmentation into discrete fragments of about 180 bp |
is |
typical hallmark of PCD |
|
| cytochrome f |
is focused on as |
possible important factor in the pathway of cell death induced by HS in unicellular algae |
unicellular algae |
| manipulation of RESPIRATORY BURST OXIDASE HOMOLOG E |
disturbs timing of |
tapetal PCD |
Arabidopsis thaliana |
| corpse clearance |
involves degradation of |
nucleic acid species |
|
| cysteine proteases |
are stored in |
ER-derived compartments |
Solanum lycopersicum; Arabidopsis thaliana |
| aleurone degeneration |
is associated with |
autolytic features |
Triticum aestivum |
| VASCULAR-RELATED NAC-DOMAIN (VND) 6 and (ANAC030, VND7, AT1G71930) |
directly upregulate |
XYLEM SERINE PROTEASE (XSP) 1 |
|
| Arabidopsis Nudix hydrolase 7 |
has been implicated in |
cell death |
Arabidopsis thaliana |
| accumulation of reactive oxygen species (ROS) |
implicated in |
dPCD triggering |
|
| apoplast |
is source of |
pPCD triggers |
|
| strong Ca2+ influx and complete destruction of membrane integrity |
activate |
METACASPASE4 (AtMC4, AtMCP2d, MC4, MCA4, MCP2d, AT1G79340) from inactive zMC4 |
Arabidopsis thaliana |
| early lesion leaf 1 (ell1) mutant |
exhibits abnormal |
programmed cell death (PCD) |
Oryza sativa |
| SOBIR |
associates with BAK1 to mediate |
pPCD |
|
| positive SA–ROS feedback loop |
can be considered as |
pPCD trigger |
|
| metacaspases |
promote |
programmed cell death (PCD) |
|
| (ANAC012, AtSND1, NAC012, NST3, SND1, AT1G32770) |
directly activates expression of |
protease-associated domain-containing vacuolar sorting receptor |
Arabidopsis thaliana |
| (PXY, TDR, AT5G61480) |
possibly regulates |
tapetum PCD |
Oryza sativa |
| cystein protease inhibitors |
are specific inhibitors of |
PCD in plant cells |
|
| ethylene production and formation of reactive oxygen species (ROS) |
participate in |
signal transduction events involved in programmed cell death (PCD) |
|
| BnaNAC60 devoid of transmembrane domain overexpression |
induces |
hypersensitive response-like cell death |
Nicotiana benthamiana; Brassica napus |
| (smB, SmBb, AT4G20440) |
controls |
cell-autonomous program |
Arabidopsis thaliana |
| cysteine proteases |
are transported to |
vacuole |
Arabidopsis thaliana |
| ACAULIS 5 (ACL5, AT5G19530) -thermospermine-SUPPRESSOR OF ACAULIS 51 (SAC51, AT5G64340) regulation pathway |
promotes expression of |
XYLEM CYSTEINE PROTEASE (XCP) 1, (XCP2, AT1G20850) and XYLEM SERINE PROTEASE (XSP) 1 |
|
| (PXY, TDR, AT5G61480) |
directly regulates |
OsC6 |
Oryza sativa |
| Os03g59090 |
is homolog of |
LETHAL LEAF SPOT1 (ACD1, LLS1, PAO, AT3G44880) |
Oryza sativa |
| (ATL55, ATRING1, RING1, AT5G10380) |
is involved in |
triggering of the programmed cell death (PCD) pathway |
Arabidopsis thaliana |
| AGPs |
are implicated in |
programmed cell death |
|
| reactive oxygen species (ROS) |
are crucial players in |
apoptotic mechanisms |
Arabidopsis thaliana |
| butylated hydroxytoluene (BHT) |
delays |
programmed cell death (PCD) |
Triticum aestivum |
| Os03g59090 |
is up-regulated in |
(PXY, TDR, AT5G61480) mutant |
Oryza sativa |
| caspase-like activity |
is suggested to be required for |
execution of plant programmed cell death (PCD) |
Arabidopsis thaliana |
| cluster i in DE-HCA |
was enriched for GO terms including |
programmed cell death (PCD) involved in cell development, monoterpene biosynthesis, and lignan biosynthesis |
Picea abies |
| full-length BnaNAC60 overexpression |
does not induce |
hypersensitive response-like cell death |
Nicotiana benthamiana; Brassica napus |
| lesion-mimic mutants (LMMs) related to excessive reactive oxygen species (ROS), damaged cell structure, and DNA degradation |
explain |
molecular mechanisms and signaling pathways governing programmed cell death (PCD) occurrence |
|
| comet assay |
determines |
degree of DNA fragmentation |
|
| multi-functional transcription factors (TFs) in specific gene-regulatory modules |
link |
diverse biological processes |
Zea mays |
| programmed cell death and abscission in leaves |
regulation remains unclear |
understanding of regulation |
Arecaceae; Aponogeton madagascariensis; Monstera |
| (AtMC9, AtMCP2f, MC9, MCP2f, AT5G04200) in tracheary elements (TEs) |
might have a pre mortem function in reducing |
autophagy levels |
Arabidopsis thaliana |
| clusters of genes |
provide |
unique transcriptional signatures for different plant PCD types |
|
| VASCULAR-RELATED NAC-DOMAIN (VND) 6 and (ANAC030, VND7, AT1G71930) |
directly upregulate |
XYLEM CYSTEINE PROTEASE (XCP) 1 |
|
| maize (Zea mays) TNP cell death |
was not compromised in |
(ATEDS1, EDS1, AT3G48090) silencing line |
Nicotiana tabacum |
| developmental responses to Plant Elicitor Peptide (PEP) treatment |
are accompanied by |
induction of differentiation via activation of developmental programmed cell death (dPCD)-related genes |
Arabidopsis thaliana |
| infiltration of 1 μM FB1 solution into (ATKTI1, AtKTI4, KTI1, AT1G73260) RNAi-silenced line 16 |
results in formation of confluent lesions within |
1 week |
Arabidopsis thaliana |
| apoptosis/PCD components |
are found in |
plant cells undergoing PCD |
|
| SI (self-incompatibility) induction |
causes high levels of |
cytosolic cytochrome c (cyt c) |
Papaver |
| precocious entry into PCD |
occurs without |
oxidative burst |
Daucus carota L. |
| Transglutaminases |
are responsible for |
formation of apoptotic bodies in animal PCD |
animals |
| tapetal PCD |
began prematurely in |
mutant anthers |
Zea mays |
| dead cells |
accumulated in |
cell division zone of root apical meristem (RAM) |
Arabidopsis thaliana |
| (ARC2, CH-CPN60A, CPN60A, Cpn60alpha1, CPNA1, SLP, AT2G28000) mutants H840A and D841V |
induce |
hypersensitive response (HR) |
Nicotiana benthamiana |
| transglutaminase |
was found to participate in |
PCD and regulate flower life span |
Nicotiana tabacum |
| TUNEL-positive nuclei distribution |
spreads to |
whole pericarp |
Hordeum vulgare |
| vacuolar processing enzymes (VPEs) |
have been identified as |
higher plant caspases with caspase-1-like activity |
|
| ultrastructural markers of PCD in vacuolate microspores |
included |
chromatin condensation at the periphery of the nucleus |
Brassica napus |
| cytochrome c (cyt c) |
is not detected in cytosol at B1, B2, and B3 stages |
cytosolic localization |
|
| caspase-like independent PCD |
reported in |
other plants |
|
| putative Scots pine MCA |
is |
1257 bp long cDNA fragment |
Pinus sylvestris |
| early lesion leaf 1 (ell1) mutant |
exhibits |
cell death |
Oryza sativa |
| programmed cell death (PCD) |
results in |
DNA degradation |
|
| maize (Zea mays) TNP |
induces cell death in |
Nicotiana tabacum |
Zea mays; Nicotiana tabacum |
| cytochrome c (Cc) |
may trigger or modulate |
metacaspase activity |
plants |
| PCD execution |
is initiated upon |
triggering signals |
|
| MAPK9 accumulation and phosphorylation |
results in |
cell death induction |
Brassica napus |
| vacuolar processing enzymes (VPE, legumains) |
participate in |
PCD of plants |
|
| latrunculin B (LatB) |
stimulates |
DNA fragmentation |
Papaver |
| Mitogen Activated Protein Kinase (MAPK) |
have been shown to play a role in |
programmed cell death (PCD) |
|
| impairment of ASC metabolism and ineffective DNA repair |
can reasonably affect |
PCD activation |
Daucus carota L. |
| ozone treatment |
affects expression of genes involved in |
abscisic acid (ABA) metabolism |
Oryza sativa |
| SALT TOLERANCE ZINC FINGER (STZ, ZAT10, AT1G27730) and its homologs |
activate |
SERINE CARBOXYPEPTIDASE-LIKE 48 (scpl48, AT3G45010) |
Arabidopsis thaliana |
| spontaneous PCD of (AT-SYR1, ATSYP121, ATSYR1, PEN1, SYP121, SYR1, AT3G11820) (ATSYP122, SYP122, AT3G52400) |
shows high similarity to |
ozone-induced PCD |
Arabidopsis thaliana |
| proteolysis by cysteinyl Asp-specific proteases (caspases) |
is tightly regulated during |
PCD process |
|
| prolonged expression of Sar1-GTP |
causes |
cell death |
plant cells |
| poly [ADP-ribose] polymerase 1 (PARP-1) |
is |
mediator of cell death |
|
| PCD process in gymnosperm seed development |
involves |
degeneration of narrow, unicellular layer lining corrosion cavity |
gymnosperms |
| mitochondrial permeability transition (MPT) |
is significant during |
apoptosis |
|
| mitochondrial permeability transition (MPT) |
promoted |
mitochondria inner membrane permeabilization |
Arabidopsis thaliana |
| rupture of the mitochondrial outer membrane |
resulted in |
release of cytochrome c |
Arabidopsis thaliana |
| ethylene |
is trigger in |
PCD |
|
| wild-type CC-NB-ARC domain |
does not induce |
hypersensitive response (HR) |
Nicotiana benthamiana |
| p56-MAPK |
is involved in |
programmed cell death (PCD) |
Papaver |
| cell condensation |
occurred in cells |
heat-treated cells |
Arabidopsis thaliana |
| FLU(ΔTM-CC)/flu seedlings |
showed |
necrotic phenotype |
Arabidopsis thaliana |
| autonomous forms of differentiation-induced dPCD |
less closely related to |
forms of pPCD |
|
| PUTATIVE ASPARTIC PROTEINASE A3 (AtPaspA3, PaspA3, AT4G04460) |
induction occurs in |
Arabidopsis thaliana |
Arabidopsis thaliana |
| VND-INTERACTING 2 (ANAC083, NAC083, VNI2, AT5G13180) |
suppresses expression of genes involved in |
programmed cell death (PCD) process |
|
| powdery mildew fungus Gc |
does not elicit |
host cell death |
Arabidopsis thaliana |
| caspase-mediated PCD |
has been extensively addressed in |
plant cells |
|
| cell death executors and regulators defined in animal PCD |
are largely missing from |
Arabidopsis genome |
Arabidopsis thaliana |
| oxidative burst |
typically anticipates entry of cells into |
programmed cell death (PCD) |
|
| fusion of very large vacuoles with plasma membrane |
would determine |
cell shrinkage |
|
| light and electron microscopy observations |
suggested |
possible, though rare, occurrence of PCD in topo I-depleted cells treated with UV-C |
|
| ethylene |
regulates |
cell death during cereal endosperm development |
|
| ascorbic acid (AsA) |
delays |
programmed cell death (PCD) |
Triticum aestivum |
| up-regulation of Haem oxygenase-1 (HO-1) expression |
delays programmed cell death (PCD) through the down-regulation of |
hydrogen peroxide (H2O2) production |
Triticum aestivum |
| coenocytic endosperm |
is when |
PCD events are only observed within nucellus |
Hordeum vulgare |
| activation and specific cleavage of PARP |
are essential for |
PCD progression induced by heat shock |
Nicotiana tabacum |
| CM103E04 |
is up-regulated |
in transgenic T-34 |
Gossypium hirsutum |
| salicylic acid (SA) signaling |
potentiated |
PAD4-dependent HR-like response |
Arabidopsis thaliana |
| a MAPK, most likely p56 |
participates in initiating |
PCD signalling cascade |
|
| H2O2 |
can trigger |
cell death |
|
| cyclosporine A (CsA) |
retarded |
mitochondrial dysfunction |
Arabidopsis thaliana |
| hydrogen peroxide (H2O2) scavenging |
delays |
gibberellic acid (GA)-induced programmed cell death (PCD) |
Triticum aestivum |
| pollen tubes |
undergo demise after fulfilling |
their functions |
Arabidopsis thaliana |
| NaCl-induced hyperosmotic stress |
induces |
programmed cell death (PCD) |
Nicotiana tabacum |
| production of cell-death signal in bak1-4 bkk1-1 |
is likely controlled by |
unknown developmental cues |
Arabidopsis thaliana |
| reactive oxygen species |
may be involved in |
animal PCD |
|
| (ATKTI1, AtKTI4, KTI1, AT1G73260) overexpression line (S8 and S13) |
shows reduced |
lesion formation at high FB1 concentrations (10 μM) |
Arabidopsis thaliana |
| (ATKTI1, AtKTI4, KTI1, AT1G73260) gene |
is likely to be involved in control of |
FB1-induced cell death |
Arabidopsis thaliana |
| percentage of cells in PCD in AT1-β/22 population at 24 h |
decreased to |
<1% and 1.2% (early and late PCD, respectively) |
|
| cysteine protease mcll-Pa |
executes |
PCD during Norway spruce embryogenesis |
Picea abies |
| mitochondrial dysfunction |
plays vital role in |
Al-induced protoplast death |
Arabidopsis thaliana |
| ET |
is thought to potentiate |
senescence-related PCD |
Arabidopsis thaliana |
| Nicotiana plumbaginifolia GBP1 overexpression |
results in |
necrotic lesions |
Nicotiana plumbaginifolia |
| (AOX1A, ATAOX1A, AtHSR3, HSR3, AT3G22370) |
plays a role in |
Al-induced protoplast death |
Arabidopsis thaliana |
| (LTP, LTP7, AT2G15050) family genes |
down-regulation might block |
tapetum PCD |
Oryza sativa |
| Mitogen Activated Protein Kinase (MAPK) |
are known to signal to |
programmed cell death (PCD) |
|
| ROS |
control |
programmed cell death (PCD) |
|
| lesion-mimic mutants (LMMs) |
provide |
tool to reveal molecular mechanisms determining programmed cell death (PCD) |
|
| necrotic lesions in (ELL1, FK, HYD2, AT3G52940) mutant leaves |
indicate |
occurrence of cell death in leaves |
Oryza sativa |
| metacaspases |
assigned different roles in |
dPCD and pPCD |
|
| autophagy modulation |
functionally implicated in |
pPCD as effector |
|
| lytic enzymes involved in (ESP, ESR, TASTY, AT1G54040) dRCA |
could be induced upon |
sensing of imminent death from mechanical pressure |
Arabidopsis thaliana |
| (AT-SYR1, ATSYP121, ATSYR1, PEN1, SYP121, SYR1, AT3G11820) (ATSYP122, SYP122, AT3G52400) double mutant at 2.5-weeks time-point |
is preparing for initiation of |
PCD |
Arabidopsis thaliana |
| infiltration of 2.5 μM FB1 solution into (ATKTI1, AtKTI4, KTI1, AT1G73260) RNAi-silenced line 16 |
results in formation of confluent lesions within |
4 days |
Arabidopsis thaliana |
| actin punctate foci formation |
may be involved in |
programmed cell death (PCD) |
Papaver |
| brown spots on leaves |
is consequence of |
chlorenchyma cell death |
Aechmea 'Maya' |
| aluminium (Al) exposure |
induces caspase-3-like protease activation within |
30 minutes to 1 hour timeframe |
|
| aluminum (Al)-induced caspase-3-like activation |
was detected using |
FRET probe |
Arabidopsis thaliana |
| zinc protoporphyrin IX (ZnPPIX) pretreatment before gibberellic acid (GA) exposure |
accelerates significantly |
gibberellic acid (GA)-induced programmed cell death (PCD) |
Triticum aestivum |
| cell row numbers in the pericarp |
decrease between |
3 and 10 DAF |
Hordeum vulgare |
| developmental programmed cell death (PCD) |
has been found to occur during |
root cap shedding |
|
| hallmarks of programmed cell death (PCD) |
have not yet been described for |
pith autolysis |
|
| cysteine proteases (CPs) |
contribute to |
regulation of programmed cell death |
|
| DNA laddering during salt stress |
can be abrogated by |
addition of Zn2+ |
Micrasterias denticulata |
| DNA laddering after freeze-thaw procedure |
points towards |
fast activation processes of responsible endonuclease |
Micrasterias |
| release of cytochrome f in the cytosol |
highlights the role of |
cytochrome f in cell death |
Solanum melongena |
| chloroplast |
could have |
central regulatory role in integrating stress and/or PCD signals in unicellular organisms |
unicellular organisms |
| trypsin inhibitors |
are components of |
complex machinery of PCD |
|
| U0126 pre-treatment |
alleviates |
SI-induced caspase-3-like activity |
|
| (YAO, AT4G05410) and Greenberg (2006) |
suggested that |
chlorophyll breakdown products could induce programmed cell death (PCD) |
|
| FRET probe |
has been successfully used to monitor |
UV-induced caspase-3-like activation in Arabidopsis protoplasts |
Arabidopsis thaliana |
| TUNEL staining |
labels |
3′-OH ends produced as a result of DNA fragmentation |
|
| anion current increases |
are reported to be a necessary event to achieve |
cell death by the elicitor cryptogein |
Arabidopsis thaliana |
| mesophyll cells at petal and sepal margins in Alstroemeria |
have completely degenerated by time flowers have opened, indicating |
cell death occurring from earliest stages of flower development |
Alstroemeria |
| DNA of sorbitol-treated cells |
does not show |
ladder-like pattern on agarose gel |
Micrasterias denticulata |
| PCD hallmarks in Micrasterias upon H2O2 induction |
have recently been described |
|
Micrasterias denticulata |
| (ATKTI1, AtKTI4, KTI1, AT1G73260) protein |
antagonizes |
pathogen-induced cell death |
Arabidopsis thaliana |
| jasplakinolide (Jasp) |
stimulates |
DNA fragmentation |
Papaver |
| ozone treatment |
affects expression of genes involved in |
pathogen and disease resistance |
Oryza sativa |
| mitochondria inner membrane permeabilization |
caused |
rupture of the mitochondrial outer membrane |
Arabidopsis thaliana |
| specific proteases |
promote |
PCD events |
Hordeum vulgare |
| subsequent Ca 2+ -dependent signal transduction |
might be involved in |
PCD processes in the host |
Brassica napus |
| DNA laddering in green algae |
response to |
heat in Volvox carteri and Chlamydomonas reinhardtii |
Volvox carteri; Chlamydomonas reinhardtii |
| impairment of mitochondrial metabolism |
subsequently leads to |
activation of caspase-like protease |
Nicotiana tabacum |
| mitochondria and chloroplasts |
could have |
role in PCD involving some of their own molecules |
|
| programmed cell death (PCD) |
is |
multi-step process that is strictly and genetically controlled |
|
| cytoplasmic acidification |
is implicated in |
dPCD processes |
|
| certain subunits of the proteasome |
possess |
caspase-like activities |
|
| NB mutants T557S and D630E |
induce relatively slow |
hypersensitive response (HR) |
Nicotiana benthamiana |
| PtaRHE1 overexpression |
induces up-regulation of |
programmed cell death-related genes |
Nicotiana tabacum |
| (ATNHX7, ATSOS1, SOS1, AT2G01980) root tip region |
shows |
cell death |
Arabidopsis thaliana |
| mitochondrial swelling |
occurs prior to |
cell death |
|
| dithiothreitol (DTT) |
delays |
programmed cell death (PCD) |
Triticum aestivum |
| ROS-dependent mitochondrial dysfunction |
was |
early event in aluminum (Al)-induced protoplast programmed cell death (PCD) |
Arabidopsis thaliana |
| energy source supplementation to cut flowers |
delays appearance of |
important biochemical events reported in different types of plant programmed cell death (PCD) and apoptosis in animal cells |
|
| internucleosomal DNA fragmentation |
occurs during |
programmed cell death (PCD) |
|
| proteases |
are responsible for |
DNase activation |
Nicotiana tabacum |
| induction of nucleases |
is associated with |
endosperm development |
|
| senescence |
is considered to be |
developmental type of programmed cell death (PCD) |
|
| osmotic component of salt stress |
does not cause |
DNA laddering in Micrasterias |
Micrasterias |
| cytochrome c |
triggers |
apoptosis |
mammals; plants |
| cytochrome f |
could have |
similar role in C. saccharophila |
Chlamydomonas saccharophila |
| accumulation of large amounts of reactive oxygen species (ROS) |
leads to |
cell death in (ELL1, FK, HYD2, AT3G52940) mutant |
|
| (CRK28, AT4G21400) overexpression |
causes |
cell death |
Arabidopsis thaliana |
| mycotoxin-mediated cell death |
depends on |
VPE |
|
| singlet oxygen (1O2) production in chloroplasts |
plays key role in |
programmed cell death (PCD) regulation |
Arabidopsis thaliana |
| programmed autolysis |
is initiated before |
cell death |
|
| accelerated lesion formation in RNAi-silenced plants |
is evident at concentrations of |
≤2.5 μM FB1 |
Arabidopsis thaliana |
| heat treatment at 55 °C |
induced |
apoptotic-like (AL)-PCD |
Arabidopsis thaliana |
| poly [ADP-ribose] polymerase 1 (PARP-1, spot 57) |
is |
another PCD protein |
Chinese fir |
| (ATEDS1, EDS1, AT3G48090) mutant alleles |
partially rescue |
lesion-mimic phenotype |
Arabidopsis thaliana |
| tetra-peptide inhibitors |
pre-treatment reduces |
DNA fragmentation levels |
|
| SI-induced incompatible pollen extracts |
generates |
24-kDa PARP cleavage product |
|
| cell condensation in dark-grown heat-treated cells |
was much more extreme in |
cell condensation in light-grown heat-treated cells |
Arabidopsis thaliana |
| various plant hormones |
are involved in |
hrp-regulated plant PCD |
|
| (BFN1, ENDO1, AT1G11190) promoter activation |
was observed in |
pith of mature stems in cells targeted for autolysis |
Solanum lycopersicum |
| overexpression of (BAP1, AT3G61190) or (BAL, BAP2, AT2G45760) with their partner (BON, BON1, CPN1, AT5G61900) |
inhibits |
PCD induced by pathogens |
Arabidopsis thaliana |
| (ATCMPG1, CMPG1, AT1G66160) |
is required for |
INF1-mediated cell death |
|
| impairment of mitochondrial metabolism |
subsequently leads to |
release of cytochrome c |
Nicotiana tabacum |
| cytochrome f |
has meaning and mode of action in |
PCD pathway |
|
| cysteine protease inhibitor E-64c |
strongly suppresses |
internucleosomal fragmentation of genomic DNA |
Nicotiana tabacum |
| (BFN1, ENDO1, AT1G11190) promoter activation |
occurred during |
seed development |
Arabidopsis thaliana |
| iso-osmotic sorbitol treatment |
does not result in |
PCD hallmarks |
Micrasterias |
| ionic component of salt stress |
rather than osmotic component |
leads to PCD in Micrasterias |
Micrasterias |
| SERINE CARBOXYPEPTIDASE-LIKE 48 (scpl48, AT3G45010) |
acts as |
key regulator in programmed cell death (PCD) |
Arabidopsis thaliana |
| H840A and D841V mutants |
are the fastest at inducing |
hypersensitive response (HR) |
Nicotiana benthamiana |
| PCD machinery |
might be somewhat conserved between |
animal and plant kingdoms |
|
| genes related to jasmonic acid metabolism |
are differentially regulated in |
one of the substitution lines |
Oryza sativa |
| cyclosporin A (CsA) |
reduces |
NaCl-induced cell death |
Nicotiana tabacum |
| modification of cell wall structures and selective autolysis of organelles |
are similar in many ways to |
programmed cell death |
|
| (smB, SmBb, AT4G20440) |
activates |
set of programmed cell death (PCD)-specific downstream transcription factors |
Arabidopsis thaliana |
| combined viability and cell death stains |
indicated |
presence of dead LRP-overlying cells |
Arabidopsis thaliana |
| phosphomimetic lesions in (ATMSL10, MscS-LIKE 10, MSL10, AT5G12080) N terminus |
prevented |
PCD in response to cell swelling |
Arabidopsis thaliana |
| (ATMSL10, MscS-LIKE 10, MSL10, AT5G12080) gain-of-function alleles |
show phenotypic effects such as |
ectopic cell death |
Arabidopsis thaliana |
| ana046 (ANAC087, AT5G18270) mutant |
exhibits increased number of |
living columella cells comparable with that found in atg mutants |
Arabidopsis thaliana |
| Arabidopsis type II metacaspases (MC4–9) |
have |
various roles in cell death and immunity |
Arabidopsis thaliana |
| HyPRP1 |
regulates |
programmed cell death (PCD) |
|
| tobacco leaf cells |
demonstrate |
internucleosomal DNA fragmentation |
Nicotiana tabacum |
| developmental programmed cell death (PCD) |
has been found to occur during |
leaf morphogenesis |
|
| caspase-3-like activity |
increased in |
Chlorella saccharophila during PCD |
Chlorella saccharophila |
| RPW8.2 accumulation in punctate spots |
results in subsequent |
cell death |
Arabidopsis thaliana |
| tobacco suspension cells |
demonstrate |
internucleosomal DNA fragmentation |
Nicotiana tabacum |
| Thaxtomin A (TXT) |
induces |
cell death |
|
| (BFN1, ENDO1, AT1G11190) promoter activation |
was visualized during |
vascular cell differentiation process |
Arabidopsis thaliana; Solanum lycopersicum |
| reduction in photochemical efficiency |
during onset of |
methyl jasmonate-induced cell death |
|
| (ATMSL10, MscS-LIKE 10, MSL10, AT5G12080) with four residues replaced with alanine ( 7A-GFP) |
produces |
constitutive cell death in transient expression system |
Arabidopsis thaliana |
| untagged (ATMSL10, MscS-LIKE 10, MSL10, AT5G12080) from endogenous promoter in -1 mutant background |
produced |
cell swelling-induced PCD at levels comparable to wild type |
Arabidopsis thaliana |
| (ATMAPK6, ATMPK6, MAPK6, MPK6, AT2G43790) mutant |
suppresses |
deregulated cell death triggered by fumonisin B1 |
Arabidopsis |
| accumulation of Pheide b and HMPheide a |
results in |
cell death |
|
| programmed cell death (PCD) |
is characterized by |
progressive disintegration of the cell's organization |
Brassica napus |
| tracheary elements |
are |
dead at maturity |
|
| (BFN1, ENDO1, AT1G11190) promoter activation |
was not detected when plant was challenged with |
fumonisin B1 |
Arabidopsis thaliana |
| endosperm layer development |
involves |
programmed cell death (PCD) |
|
| salt-induced PCD in plants and yeast |
caused by |
ionic stress |
|
| Ca2+-dependent endonucleases |
associated with |
apoptosis |
|
| active metabolism |
points towards |
programmed cell death and not necrotic, accidental cell death event |
Micrasterias |
| endo-polygalacturonase (endo-PG) of Sclerotinia sclerotiorum |
could induce |
PCD in plant cells |
Sclerotinia sclerotiorum |
| salt stress-induced DNA laddering |
described in |
barley roots |
Hordeum vulgare |
| appearance of PCD hallmarks |
accompanied by |
active metabolism measured by viability assay, pigment composition, photosynthesis, and respiration |
Micrasterias |
| AVR3a |
potentially interacts with |
protein involved in INF1-mediated PCD |
Phytophthora infestans |
| N gene-mediated cell death |
depends on |
VPE |
|
| boehmerin-mediated cell death |
differs from |
harpin-mediated cell death |
|
| vacuolar processing enzyme (VPE), also called legumain |
is |
plant protease with caspase-like activity involved in plant PCD |
|
| adenosine triphosphate (ATP) |
is necessary to prevent |
DNA fragmentation |
|
| developmental programmed cell death (PCD) |
has been found to occur during |
organ senescence |
|
| ethylene |
may activate |
cell death in abscission zone |
Rosa sp. |
| C. saccharophila |
was used as |
model system to identify molecules involved in HS-induced PCD |
Chlamydomonas saccharophila |
| generation of reactive oxygen species (ROS) |
directly or possibly through mediating other processes induced |
mitochondrial permeability transition (MPT) |
Arabidopsis thaliana |
| TUNEL-labelled nuclei at 6 DAF |
appear in |
ventral areas |
Hordeum vulgare |
| calcium |
is associated with |
cell death |
Arabidopsis thaliana |
| specific autolysis-related hydrolases |
are recruited to carry out |
cell-autonomous, active, and regulated cell death |
|
| salt stress-induced DNA laddering |
described in |
rice root tips |
Oryza sativa |
| plant genomes |
contain |
up to eight distinct caspase-like activities |
|
| SALT TOLERANCE ZINC FINGER (STZ, ZAT10, AT1G27730) and its homologs |
activate |
XYLEM CYSTEINE PEPTIDASE 1 (XCP1, AT4G35350) |
Arabidopsis thaliana |
| D630E mutation |
leads to |
visual necrosis |
Nicotiana benthamiana |
| JA |
can have |
anti-PCD functions |
Arabidopsis thaliana |
| specific protease inhibitors |
play crucial roles in |
cellular regulation of proteases during PCD process |
|
| metacaspases |
participate in |
PCD of plants |
|
| putative PCD-related proteins (spot 57 and spot 74) down-regulation |
coincident with |
elimination of subordinate embryos and suspensor degeneration |
Chinese fir |
| singlet oxygen (1O2) |
can function as signal leading to |
cell death |
Arabidopsis thaliana |
| zinc protoporphyrin IX (ZnPPIX) addition |
reverses the prevention of |
gibberellic acid (GA)-induced programmed cell death (PCD) prevention by haematin or carbon monoxide |
Triticum aestivum |
| Arabidopsis δVPE |
has |
proven caspase-1-like activity |
Arabidopsis thaliana |
| programmed cell death (PCD) |
is implicated in |
senescence, abscission, and differentiation processes |
Arabidopsis thaliana; Solanum lycopersicum |
| senescence |
is likely to be distantly related to |
other plant PCD processes |
|
| several seed tissues |
undergo |
programmed cell death (PCD) as part of normal development |
|
| Avr1b |
suppresses |
mitochondrial BAX protein |
Phytophthora sojae |
| senescence in Arabidopsis |
has been discussed as |
cell-death process |
Arabidopsis |
| VIGS of CaPAL1 |
compromised |
cell death during Xcv infection |
Capsicum annuum |
| excess amounts of H2O2 |
leads to |
cell death |
|
| HvVPE4 |
is weakly similar to |
PCD-type of VPEs, including Arabidopsis δVPE, tobacco NtPB3, and tomato VPE |
Hordeum vulgare; Arabidopsis thaliana; Nicotiana tabacum; Solanum lycopersicum |
| pith autolysis |
is very similar to |
lysigenous aerenchyma |
|
| programmed cell death (PCD) processes in Alstroemeria petals |
are initiated extremely early at similar location on petals to that observed for |
expression of (BFN1, ENDO1, AT1G11190) promoter in tomato petal margins |
Alstroemeria; Solanum lycopersicum |
| Hoechst positive nuclei |
are detected in cells treated with |
2 h and 24 h cytosolic extracts |
Chlorella saccharophila |
| programmed cell death (PCD) |
was correlated with |
alteration in the activity of metabolic enzymes |
Oryza sativa |
| Constitutive overexpression of CaPAL1 in Arabidopsis |
conferred |
cell death |
Arabidopsis thaliana |
| drought |
was shown to induce |
programmed cell death (PCD) |
|
| cell death induced by osmotic stress |
requires |
cellular metabolism |
Nicotiana tabacum |
| cystatin genes |
have demonstrated physiological functions in |
programmed cell death (PCD) |
|
| elevation of PA levels |
may lead to |
apoptosis |
|
| sucrose supplementation to cut flowers |
delayed |
cytochrome c (cyt c) release |
Tulipa gesneriana |
| sucrose supplementation to cut flowers |
delayed |
petal senescence |
Tulipa gesneriana |
| internucleosomal DNA fragmentation |
is connected with action of |
cysteine proteases |
Nicotiana tabacum |
| lysigenous aerenchyma |
forms in |
dryland species under adverse flooding conditions |
|
| necrotic-like PCD |
is considered |
a type of PCD |
|
| DNA laddering after CdSO4 treatment |
detected in |
tobacco BY-2 cells |
Nicotiana tabacum |
| caspase-3-like activity in Micrasterias after H2O2 treatment |
abrogated by |
specific caspase-3 inhibitor |
Micrasterias |
| decrease in caspase-3-like protein amount |
observed during |
apoptotic-like cell death in UV-C treated unicellular cells of Chlamydomonas reinhardtii |
Chlamydomonas reinhardtii |
| similar signalling mechanism involving (PLD, PLDALPHA1, AT3G15730) and PLC |
could play |
pivotal role during salt stress-induced PCD in Micrasterias |
Micrasterias |
| Scots pine metacaspase |
was 89% identical to |
Norway spruce type-II metacaspase |
Pinus sylvestris |
| increase in RbCP1 expression |
collectively suggest |
progression of abscission in rose petals may be associated with gradual cell death |
Rosa sp. |
| Rose Bengal (RB) treatment at 0.5 μM in dark-grown cells |
does not induce |
programmed cell death (PCD) |
Arabidopsis thaliana |
| apoptosis |
is |
most widely studied form of PCD |
|
| nuclease induction |
is strongly associated with |
hypersensitive response (HR) |
|
| programmed cell death (PCD) |
is known to occur progressively during |
development of different anther tissues |
|
| metacaspase |
is possible executor of |
plant PCD |
|
| fluorescent caspase-3 substrate Ac-DEVD-AMC |
is used as tool to quantify |
SI-induced caspase-3-like/DEVDase activity |
|
| cysteine protease expressed in early stage Chinese fir seed development |
mediates |
PCD during embryonic patterning |
Chinese fir |
| DEGs encoding anti-cell death inhibitor-like products |
are up-regulated in |
transgenic T-34 |
|
| PCD |
is executed in plant cells by |
cysteine proteases (metacaspases and VPEs) |
Arabidopsis thaliana |
| PCD signalling cascade |
commits |
pollen tube to die |
|
| chloroplast-free light-grown cultures established using norflurazon, spectinomycin, and lincomycin |
responded to heat treatment with increased |
apoptotic-like (AL)-PCD |
Arabidopsis thaliana |
| endosperm of monocot cereal grains |
goes through programmed cell death upon maturation |
|
|
| genes related to general disease resistance |
are differentially regulated in |
one of the substitution lines |
Oryza sativa |
| cysteine proteinase gene |
was found to be expressed only in |
inner integument undergoing PCD |
Brassica napus |
| cysteine proteinase (caspase-like protein) |
is |
identified PCD-related protein |
Chinese fir |
| cytosolic acidification |
is hallmark of |
programmed cell death |
Arabidopsis thaliana |
| succession of cell death events |
opens the possibility that |
developmentally controlled cell death execution is evolutionarily conserved in land plants |
|
| single and double mutants of arh1-2, fei1-C, and fei2-C |
exhibit |
enhanced programmed cell death (PCD) of the endodermis |
Arabidopsis thaliana |
| Capsicum annuum HYPER-SENSITIVE RESPONSE-RELATED PROTEIN 1 (CaHyPRP1) overexpression |
causes |
chlorosis and cell death spots |
Nicotiana benthamiana |
| HvVPE4 |
plays a role in |
PCD events in pericarp |
Hordeum vulgare |
| tapetal dysfunction in the Arabidopsis mutant (MS1, AT5G22260) |
may subsequently induce |
PCD in the microspores |
Arabidopsis thaliana |
| anion channel inhibitors alone |
induced |
slight cell death |
Arabidopsis thaliana |
| overexpression of IPG-1 |
might inhibit |
PCD |
Brassica napus |
| salt stress-induced DNA laddering |
is |
hallmark of PCD |
|
| metacaspase (MCA) |
has been shown to have role in |
activation and/or execution of PCD in plants |
Plantae |
| enhancement of catalase (CAT) and ascorbate peroxidase (APX) activities or transcripts |
results in a delay in |
programmed cell death (PCD) |
Triticum aestivum |
| breakdown of cellular compartmentalization |
is a feature of |
programmed cell death |
|
| chloroplast-mediated PCD machinery |
is also present in |
green algae |
green algae |
| HvVPE2a together with HvVPE2b and HvVPE2d |
might be involved in |
nucellar PCD |
Hordeum vulgare |
| Arabidopsis (ATEDR1, EDR1, AT1G08720) (ENHANCED DISEASE RESISTANCE1) |
is involved in |
cell death |
Arabidopsis thaliana |
| 50 μM CdSO4 treatment |
induces |
internucleosomal fragmentation of genomic DNA |
Nicotiana tabacum |
| pretreatment of A. thaliana cells with Gd3+ |
induces slight increase in |
cell death |
Arabidopsis thaliana |
| zinnia nuclease ZEN1 |
is responsible for |
nuclear DNA degradation during programmed cell death (PCD) associated with tracheary element (TE) differentiation |
Zinnia |
| activity increase of caspase-like enzymes |
is |
typical hallmark of PCD |
|