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nodule development

10757 relationships annotated with this phrase. Showing first 500 of 10757.
Source entity Relationship Target entity Species
nodules developed on mutant roots transformed with NCR-new35 construct showed typical zonation of indeterminate nodules with colonized cells in ZIII Medicago truncatula
GA biosynthesis and catabolism gene expression co-occurs in cells undergoing infection and/or nodule development Glycine max; Medicago truncatula
ISOPENTENYLTRANSFERASE (GmIPT3) is expressed in nodule primordia Glycine max
tight regulation of CK levels is necessary for nodule maintenance Glycine max
zones of indeterminate nodules could be already identified in mutant nodules Medicago truncatula
infected cells in ZII and IZ exhibited similar morphology in mutant and WT nodules Medicago truncatula
nodules developed on NF-FN9363 roots transformed with NCR343 were functional nodules Medicago truncatula
LjHO1 mRNA level was upregulated during nodule maturation at 2 wpi Lotus japonicus
species-producing determinate nodules form nodules mainly from outer and middle cortex
Psdella mutants develop less nodules Pisum sativum
mitotic activity of meristem cells (zone I, ZI) produces new cells for all nodule tissues Medicago truncatula
LjHO2 transcript level did not significantly increase during nodule development Lotus japonicus
gibberellins (GA) promote subsequent progression of nodule development Pisum sativum
GUS expression was associated with invasion zone in 10 dpi nodules Medicago truncatula
GmINS1 RNA interference lines have 33.4% lower dry weight of large nodules than empty vector control
miR4407 is expressed in nodule primordium around root pericycle region Glycine max
NCR247 knockout causes plants to form small and white nodules
nodule-like structure formation appears to require NODULE INCEPTION (NIN)
BAP (cytokinin) application to WT pea suppressed number of nodules Pisum sativum
miR4407pro-GUS signal is lower in nodule primordium Glycine max
NCR-new35 expression is significantly lower and limited to transition zone of the nodule Medicago truncatula
nodule colonization in mutants NF-FN9363, Mtsym19 and Mtsym20 was similar to nodule colonization in Medicago truncatula dnf4 and dnf7 mutants Medicago truncatula
Mtsym20 mutant develops slightly elongated white nodules with zonation Medicago truncatula
rhizobia secrete lipochitooligosaccharides (Nod factors)
MtMATE67 gene is expressed primarily in invasion zone of mature nodules Medicago truncatula
suppression of GmINS1 reduced individual nodule size Glycine max
altering the expression of GmINS1 significantly modified nodule expansion Glycine max
na CASP::NA roots developed similar number of mature nodules to WT roots Pisum sativum
miR4407 was found to be expressed in outer cortex of mature nodule Glycine max
NF-FN9363 mutant develops slightly elongated white nodules with zonation Medicago truncatula
gibberellin (GA) promotes nodule initiation via suppression of ethylene biosynthesis Pisum sativum
gibberellin (GA) and ethylene act relatively independently to promote nodule maturation Pisum sativum
auxin transport is reported to play key role in nodule organ formation
miR4407 was found to be expressed in primordium of nascent nodule Glycine max
miR4407 expression pattern changes during nodule development Glycine max
LjHO1 protein was abundant in mature nodules at 4 and 6 wpi Lotus japonicus
loss of function della mutants inhibits spontaneous nodule formation in ccamk and CK receptor gain of function mutants Medicago truncatula
vacuoles in IZ cells of mutant nodules remained reduced in IZ cells of mutant nodules Medicago truncatula
CYCLOPS expression was detected only in mature nodule at 7 and 14 dpi Aeschynomene evenia
nodule cells in nitrogen fixation zone of mutant NF-FN9363 were devoid of rhizobia Medicago truncatula
mutants missing all DELLA genes display range of nodule types Medicago truncatula
cytokinins (CK) promotes nodule organogenesis and development
white round-shaped or slightly cylindrical nodules were formed on empty vector-transformed roots of mutant plants Medicago truncatula
miR4407 is mainly expressed in cortex and vascular bundles of developing and mature nodules Glycine max
GmINS1 RNA interference lines have 63.2% of nodules in large nodule group
(NLP4, AT1G20640) competes for binding sites on target genes with NIN (NODULE INCEPTION) Lotus japonicus
mature nodules in WT were present at 8 dpi Pisum sativum
GmSPX5/8 mediate soybean nodule growth Glycine max
During nodule development the number of rhizobia in infected cells increases dramatically
MtMATE67 transcripts are detected in all nodule zones Medicago truncatula
three GmINS1 OX lines have individual nodule size increased by 34.1%, 31.7%, and 69.6%
GmINS1 expression was strongly associated with large nodule number Glycine max
tight regulation of CK levels is necessary for nodule initiation Glycine max
auxin response promotes nodule primordia development Pisum sativum
plants with disrupted GA biosynthesis negatively impact nodule number Pisum sativum; Glycine max; Medicago truncatula
synthetic CK 6-Benzylaminopurine (BAP) can suppress nodule number Pisum sativum
P2 large nodules have 22.8% higher number of infection cells than P1
GmINS1 overexpression lines have 14.7% increase in number of infection cells
overexpression of DMI2/SYMRK kinase domain causes spontaneous nodulation
altering the expression of GmINS1 significantly modified infection cell development Glycine max
overexpression of full-length SYMRK/DMI2 leads to spontaneous nodule formation
DMI2/SYMRK kinase domain overexpression decreases nodule numbers in sunn mutants Medicago truncatula
high rates of respiration by plant mitochondria and rhizobia contributes to low oxygen concentrations around rhizobia
empty vector control plants have 71.9% of nodules in large nodule group
INCREASING NODULE SIZE1 (GmINS1) is critical gene in nodule development Glycine max
GmINS1 expression in soybean nodules directly affects nodule growth and development
GmINS1 expression was strongly associated with individual nodule weight Glycine max
dmi2-1 plants expressing wild-type gDMI2-HAST generate many nodules Medicago truncatula
P2 large nodules have 55.7% higher surface area of 100 infection cells than P1
GmINS1 and GmEXPB2 expression is associated with determinate nodule formation and expansion
three GmINS1 OX lines showed increases of 74.7%, 87.7%, and 131.4% in nodule dry weight
GmEXPB2 expression is expressed preferentially in nodule vascular trace and nodule vascular bundle (NVB) in early stages of nodule development Glycine max
dmi2-1 plants transformed with wild-type gDMI2-HAST generate large number of pink nodules Medicago truncatula
persistent meristem of indeterminate nodules generates developmental gradient of cells
legume species form indeterminate nodules
stably transformed soybean plants with GmINS1 overexpression showed significant increases in number of large nodules Glycine max
GmINS1 expression significantly promoted nodule development and expansion Glycine max
overexpressing the kinase domain or full-length DOES NOT MAKE INFECTIONS 2 (DMI2) / SYMBIOSIS RECEPTOR KINASE (SYMRK) results in spontaneous nodulation or hypernodulation phenotype in legumes
INCREASING NODULE SIZE1 (GmINS1) overexpression results in increases in infection cell abundance Glycine max
GmINS1 overexpression lines have 20.9% increase in surface area of 100 infection cells
GmINS1 overexpression led to larger infection cells Glycine max
Glyma.U014500 was named GmINS1
GmINS1 expression is associated significantly with individual nodule weight Glycine max
GmINS1 expression is expressed primarily during rapid developing stage of nodules Glycine max
restricted gas diffusion across outer cell layers of nodule contributes to low oxygen concentrations around rhizobia
GmINS1 suppression leads to more numerous and smaller nodules compared with empty vector control
GmINS1 expression is localized in nodule vascular bundle (NVB) Glycine max
GmINS1 overexpression led to higher number of large nodules (D ≥ 2 mm) Glycine max
nodule development signaling enables plants to develop functional nodules Medicago truncatula
GUS staining was observed primarily in distal invasion zone and vascular bundles in 38 dpi nodules Medicago truncatula
determinate nodules lose meristematic activity very early in nodule development
cell expansion and cell wall extension might play crucial roles in organogenesis of determinate nodules
GmINS1 overexpression lines have individual nodule size not affected compared with control roots
soybean nodules are determinate Glycine max
nodulating plants provided with bioavailable nitrogen shut down nodules
lacZ-expressing rhizobia were relatively few in 21 dpi mate67 nodules Medicago truncatula; Sinorhizobium meliloti
INCREASING NODULE SIZE1 (GmINS1) is expressed primarily in vascular bundles, cortical and parenchyma cells of nodules Glycine max
P2 large nodules contain more and larger infection cells than P1
protein level of DMI2 is important for proper function in nodule development Medicago truncatula
indeterminate nodules have persistent meristem producing meristem zone, infection zone, interzone, fixation zone, and senescence zone
mutant nodules were reduced in size compared with WT nodules Medicago truncatula
GA application inhibits spontaneous nodule formation in ccamk and CK receptor gain of function mutants Medicago truncatula
na EXPA::NA roots develop small nodules containing reduced level of rhizobial colonisation Pisum sativum
na CASP::NA roots developed many more nodules Pisum sativum
nodule inception protein (NIN) is marker gene of early nodule development Medicago truncatula
DOES NOT MAKE INFECTIONS 2 (DMI2) protein constitutively degraded by the proteasome apparatus results in suppression of nodule development signaling pathway
GmINS1 overexpression lines resulted in 67.7%, 72%, and 74.7% large nodules
double suppression of GmEXPB2 and GmINS1 resulted in decreases in size of infection cells Glycine max
oxygen concentrations around rhizobia plummet during nodule development
mate67 mutant nodules failed to develop pink color characteristic of Leghemoglobin Medicago truncatula
GmINS1 overexpression facilitates nodule expansion
MtENOD40 regulates nodule development Medicago truncatula
Medicago truncatula plants overexpressing ENOD40 exhibited accelerated nodulation Medicago truncatula
GmSPX5 overexpression increases nodule number Glycine max
abi1-1 gene introduced into Medicago truncatula enhanced Nod factor-induced gene expression Medicago truncatula
symbiosome-specific SULTR3 transporter was essential for development of functional nodules Lotus japonicus
GmEXPB2 participates in nodule development and growth Glycine max
GmINS1 participates in nodule development and growth Glycine max
GmSPX5 overexpression increases nodule fresh weight Glycine max
GmSPX5 and GmNF-YC4 could positively regulate soybean nodule development
PA level in roots decreases after 4-10 days post-nodulation Glycine max
MtNF-YA1 and MtNF-YA2 have been implicated as regulators of nodulation Medicago truncatula
SL mimics designed to inhibit nodule elongation Pisum sativum
INCREASING NODULE SIZE1 (GmINS1) suppression via RNA interference has opposite effect on nodule development and plant phenotypes Glycine max
GmINS1 overexpression lines have 27.6% higher number of large nodules than empty vector control
GmINS1 is homolog of GmEXPB2
GmNF-YC4 overexpression significantly upregulates expression of GmASL2 Glycine max
phosphorus (P) deficiency reduces nodule fresh weight Glycine max
peptide hormones have important roles in nodule development
GmSPX5 and GmNF-YC4 interaction activates GmASL6 expression Glycine max
LjNOD16 mRNA synthesis in nodules is the result of transcriptional activity of a bi-directional, nodule-specific promoter located in an intron of the LjPLPIV gene Lotus japonicus
decrease in MtNoa1/ (ATNOA1, ATNOS1, NOA1, NOS1, RIF1, SVR10, AT3G47450) expression level significantly lowered nodule number Medicago truncatula
GmNF-YC4 overexpression significantly upregulates expression of GmASL4 Glycine max
GmNF-YC4 positively regulates nodule fresh weight Glycine max
GmSPX5 is preferentially expressed in nodules
overexpression of GmSPX5 led to significant increases of soybean nodule number and fresh weight, especially under phosphate sufficient conditions
overexpression of a gene encoding ureide permease (ATUPS1, UPS1, AT2G03590) was found to enhance nodule growth, accompanying a significant increase of asparagine concentration in soybean nodules
GmEXPB2 is predominantly expressed in young nodules Glycine max
GmNF-YC4 overexpression increases nodule fresh weight Glycine max
indeterminate nodules are initiated from inner cortical cells Medicago truncatula
homologous cysteine proteases participate in legume nodule development
mineral nutrient availability adversely affects nodule development and nitrogen fixation
overexpression of GmNF-YC4 led to significant increases of soybean nodule number and fresh weight, especially under phosphate sufficient conditions
actin molecular motor myosin, thin microfilaments and thicker microfilament bundles are found surrounding symbiosomes during cell division in nodules
GmSPX5 overexpression enhances soybean nodule development Glycine max
CHH hypermethylation is a prime feature of soybean nodule methylome Glycine max
GmSPX5 overexpression particularly enhances nodule development under phosphate (Pi) sufficient conditions Glycine max
auxin promotes cortical nodule organogenesis Medicago
recognition of Nod factors (NFs) by compatible LysM-type plant receptors leads to formation of root nodules
MtDMI2 is part of nodulation signalling regulation Medicago truncatula
GmPLDα4 shows increased expression during nodule development Glycine max
increased expression of GmSPX5 and its downstream genes in other soybean organs (i.e., leaves or roots) might be caused by enhanced nodule development in OX8 and OX12 lines
gain-of-function mutations of calcium and calmodulin-dependent protein kinase (CCaMK) result in spontaneous nodules Medicago truncatula; Lotus japonicus
Interzone 2–3 is narrow, amyloplast-rich cell layer Medicago truncatula
GmEXPB2 acts in nodule development and expansion
legume nodules have central infected tissue
SERK expression has not previously been reported in nodulation
nodule morphological traits includes nodule volume Trifolium repens L.
GmNF-YC4 overexpression significantly upregulates expression of GmASL3 Glycine max
GmPLDδ1 shows increased expression during nodule development Glycine max
ACTIN and TUBULIN production supports microtubule and microfilament dynamics during nodule growth and development Glycine max
GmSPX5 is preferentially expressed in soybean nodules Glycine max
MtNF-YA1 is required for nodule meristem persistence Medicago truncatula
Ljinv1 mutant nodules display normal wild-type structure Lotus japonicus
at least 25% of extant legumes do not have infection threads
actinorhizal nodules have central vascular tissue
bacteroids form symbiosome Medicago truncatula; Lotus japonicus
increase in organic acid formation per plant in +CO2 plants is the result of more nodule fresh weight per plant
nodule formation and nitrogen fixation are highly energy-consuming processes
legume nodules have peripheral vascular system
reduced N/A invertase activity does not affect ability of the plant to form functional nodules Lotus japonicus
initial event led to evolution of two branched pathways of nodule developmental processes
(ATSERK1, SERK1, AT1G71830) is highly expressed in nodules Medicago truncatula
RNAi:: MtNoa1/ (ATNOA1, ATNOS1, NOA1, NOS1, RIF1, SVR10, AT3G47450) plants showed strong decrease in nodule primordia Medicago truncatula
RNAi:: MtNoa1/ (ATNOA1, ATNOS1, NOA1, NOS1, RIF1, SVR10, AT3G47450) plants showed strong decrease in nodule number Medicago truncatula
Zone 1 is characterized by absence of rhizobia Medicago truncatula
nodule structures are host determined
Mtnf-ya1-1 mutants have delayed and reduced nodule development Medicago truncatula
high CO2 concentrations around nodules affects nodule size Glycine max; Pisum sativum; Phaseolus vulgaris
root nodules contain differentiated bacteria (bacteroids)
development of functional nodules depends on interconnected programmes for bacterial infection and de novo organ formation
nitric oxide (NO) production was detected in functional Medicago truncatula–Sinorhizobium meliloti indeterminate nodules Medicago truncatula; Sinorhizobium meliloti
na mutant develop few nodules Pisum sativum
GmIPT3 is expressed in nodule epidermis, cortex, and symbiotic region during entire nodule development Glycine max
mGmIPT3 and GmIPT3 overexpression promoted nodule formation Glycine max
this region is composed of a single layer of cells in WT nodules Medicago truncatula
host cells and rhizobia in Zone 3 complete differentiation processes differentiation processes initiated in proximal part of zone 2 Medicago truncatula
gene encoding a zinc finger protein involved in nodule organogenesis has been shown to be expressed in vascular bundles
legumes forming indeterminate nodules form nodules from inner cell layers of the root, including the inner cortex, pericycle and endodermis
complementation of nodules was assessed based on presence of rhizobia in ZIII Medicago truncatula
miR1512 is involved in nodule development Glycine max
miR396 and MtGRF targets are expressed in mature nodules Medicago truncatula
no visible difference was detected in morphology and invasion of nodule cells in distal part of ZII of WT and mutant nodules Medicago truncatula
DsRed-fluorescent transgenic Mtsym19 and Mtsym20 roots expressing gene NCR-new35 developed elongated and pink nodules Medicago truncatula
confocal and electron microscopy used to characterize nodulation phenotype Medicago truncatula
mutant plants developed roundish or slightly cylindrical white nodules Medicago truncatula
nodules developed on roots of NF-FN9363 transformed with construct of NCR343 were elongated and pink Medicago truncatula
plants with disrupted GA biosynthesis negatively impact in some cases nodule function Pisum sativum; Glycine max; Medicago truncatula
bioactive GA levels are elevated in Lotus nodule tissue compared with uninfected roots Lotus japonicus
Zone 3 is also called nodule 'central tissue' Medicago truncatula
MtNF-YA1 expression gradually becomes more expressed in apical zone Medicago truncatula
zone 2 is pre-fixation zone Medicago truncatula
MtNF-YA1 expression follows a gradient of decreasing intensity from meristematic zone down to proximal part of infection zone Medicago truncatula
chalcone synthase gene silencing results in strongly reduced nodulation
Mtnf-ya1-1 mutants have nodules preferentially on lateral roots Medicago truncatula
symbiosomes are small cytoplasmic vesicles Medicago truncatula
MtCLE12 and MtCLE13 expression patterns overlap from primordium stage onwards Medicago truncatula
nodulation inhibition depends on long-distance mechanism
MtCLE13 gain-of-function phenotype may be absent in sunn mutants Medicago truncatula
RNAi (ATUPS1, UPS1, AT2G03590) nodules show arrest in nodule development Glycine max
D1:HyP4,11 peptide has strong effects for enhancing nodulation Medicago truncatula
formation of increasingly larger nodules with higher per nodule activity was found in the experiment
MtNF-YA1 expression at base of young developing nodules fades in mature nodules Medicago truncatula
NSP proteins have been identified in both Lotus and Medicago Lotus japonicus; Medicago truncatula
miR169 is involved in nodule development Medicago truncatula
SrPI1 transcript accumulates at very early stages, possibly in response to Nod factors Sesbania rostrata; Azorhizobium caulinodans
(ATSERK1, SERK1, AT1G71830) expression is first in cortex and vascular tissue Medicago truncatula
long-term hydroponic growth with aeration of nutrient solution with ambient air might impair formation of optimally efficient nodules
MtNF-YA1 (HAP2-1) is HAP2-1 Medicago truncatula
short- and long-term CO2 concentration around nodules is of importance for formation of efficient nodules Medicago sativa
GmINS1 overexpression significantly facilitated nodule development Glycine max
pMtNF-YA1-GUS expression is restricted to distal end Medicago truncatula
AsE246 is specifically expressed in nodules Astragalus sinicus
GmINS1 RNA interference lines have 12.4% decrease in number of infection cells
GmINS1 overexpression did not affect nodule formation Glycine max
MLD is necessary for DMI2 protein to play a fundamental role in nodule development at the very early stage Medicago truncatula
full-length DOES NOT MAKE INFECTIONS 2 (DMI2) / SYMBIOSIS RECEPTOR KINASE (SYMRK) protein overexpression generates spontaneous nodules without rhizobia infection
GmINS1 and GmEXPB2 double suppression lines have 54% decrease in number of large nodules
biological nitrogen fixation (BNF) capacity is determined largely by rhizobial infection to produce more nodules and nodule organogenesis to form more expanded nodules Glycine max
dmi2-1 roots expressing MLD point mutants have few nodules Medicago truncatula
INCREASING NODULE SIZE1 (GmINS1) expression is strongly associated with nodule development Glycine max
strain-dependent mutual recognition between nodule cells and symbiotic rhizobia continues even after endosymbiosis is established Lotus japonicus; Mesorhizobium loti
auxin transport inhibitors application is sufficient to induce nodule-like cell division Lotus japonicus
Mt ARF16a is repressor-type regulator of rhizobia infection Medicago truncatula
Legumes in the tribes Trifolieae and Fabeae form indeterminate nodules
GmINS1 RNA interference lines have individual nodule size 36.1% lower than control nodules
overexpression of intracellular kinase domain of SYMRK/DMI2 leads to spontaneous nodule formation
plants control nodule development through fine regulation of DOES NOT MAKE INFECTIONS 2 (DMI2) protein level
P2 genotype promoter is strongly associated with nodule development Glycine max
GmEXPB2 and INCREASING NODULE SIZE1 (GmINS1) synergistically control nodulation in soybean Glycine max
one pathway is necessary for cortical cell division Medicago truncatula
mature nodules contain various developmental zones Medicago truncatula
MtCLE13 is produced during nodule primordium development Medicago truncatula
tendency towards lower numbers of nodules in +CO2 treatment is not consistent with CO2 feeding accelerating development of young nodules
ethylene signaling plays central role in root-controlled restriction of nodule number Medicago truncatula
sunn mutant alleles are available in Medicago truncatula Medicago truncatula
RNAi (ATUPS1, UPS1, AT2G03590) nodules show smaller infected cells Glycine max
nodule-enhanced expression was markedly higher among TFs (92 out of 1513) than among all genes Medicago truncatula
ccamk-14 mutant shows delay of approximately 7 days in appearance of first fully colonized nodules Lotus japonicus
roots with modified miR396 activity showed no obvious defect on nodule density, morphology or cellular organization Medicago truncatula
PvNOD-41 is present exclusively in nodule uninfected cells Phaseolus vulgaris
48 h post-inoculation (hpi) is time of root hair curling and the initiation of cortical cell divisions
prSERK1::GUS expression is investigated during formation of nitrogen-fixing root nodules Medicago truncatula
LHK1 negatively regulates bacterial infection Lotus japonicus
NBCL genes in indeterminate nodules repress root identity of the nodule vascular meristem (NVM)
ectopic expression of MtCLE13 inhibited nodulation on main untransformed roots of wild-type plants Medicago truncatula
sunn-4 is much stronger allele than sunn-1 Medicago truncatula
MtCLE12 is induced upon nodulation Medicago truncatula
ectopic expression of MtCLE13 strongly suppressed nodulation in skl mutant Medicago truncatula
vacuole extension was less pronounced in nodules of FN9363, Mtsym20 and Mtsym19 Medicago truncatula
differentiated bacteroids were oriented towards large vacuoles Medicago truncatula
Mtsym19 and Mtsym20 nodules show activation of second transcriptome-switch characteristic of late Fix- mutant plants Medicago truncatula
DELLA genes expression is elevated in nodule tissue Medicago truncatula
GmINS1 and GmEXPB2 double suppression lines have 53.5% decrease in nodule dry weight
ABA can regulate nodulation in Lotus japonicus and M. truncatula Lotus japonicus; Medicago truncatula
GmPLDζ1 shows increased expression during nodule development Glycine max
nodules formed on legume roots are classified into indeterminate or determinate nodules
bacteroids in apn1 nodules appeared less dense than bacteroids in wild-type nodules Lotus japonicus
Ljnbcl1 NVB identity is lost during homeosis Lotus japonicus
cells leaving the meristem have fourfold haploid DNA content (4C) Medicago truncatula
gibberellins (GA) interact with auxin and cytokinins (CK) Pisum sativum
gibberellin (GA) play a positive role in nodule organogenesis and development
nodules in na mutant are not mature and have limited function compared with WT nodules Pisum sativum
bacterial invasion of ZIII in nodules developed on NF-FN9363 roots transformed with NCR343 was like in WT Medicago truncatula
lateral root primordium is region where nodule primordium will be formed Glycine max
white undeveloped nodules with colonized cells by rhizobia in ZII and IZ were detected on roots transformed with empty vector or with genes NCR341, NCR344 and NCR345 Medicago truncatula
cells in first layer of nitrogen fixation zone showed similar morphology in WT and all mutant nodules Medicago truncatula
GA produced in the endodermis promote nodule organogenesis Pisum sativum
developing nodules in WT were not observed until 6 dpi Pisum sativum
knockout of LjHO1 by CRISPR/Cas9 resulted in disappearance of green nodules (GN) Lotus japonicus
RNA interference of GmINS1 alone had similar effects to double suppression of GmEXPB2 and GmINS1 Glycine max
miR4407 is never expressed in symbiotic region during whole nodule development process Glycine max
abi1-1 gene introduced into Medicago truncatula enhanced hyper-nodulation phenotype Medicago truncatula
(MIR172C, AT3G11435) expression starts to drop at 14 dpi and continues to diminish up to 28 dpi nodulation time course Glycine max
rhizobia-infected nodule cells were observed in infection zone and interzone of mutant nodules Medicago truncatula
indeterminate nodules possess persistent meristem during lifespan Medicago truncatula
mutant nodules did not contain infected cells in region corresponding to mature nitrogen fixation zone of WT nodules Medicago truncatula
na mutants during time course had no developing or mature nodules observed developing or mature nodules Pisum sativum
debino1 mutant forms small and white nodules Medicago truncatula
extension of this part of nodules indicates arrest of further differentiation of infected nodule cells Medicago truncatula
plants with disrupted GA biosynthesis negatively impact nodule size Pisum sativum; Glycine max; Medicago truncatula
nodule senescence occurs at late stage of development (nodule aging)
LjHO1 mRNA level was upregulated in mature nodules at 4 and 6 wpi Lotus japonicus
high CK levels and CK-responsive gene expression are localised in developing pea nodules Pisum sativum
nodules on roots of mutants transformed with modified NCRs were small and white Medicago truncatula
indeterminate nodules are derived in part from lateral root programme
GA promote nodule organogenesis and nodule development in inner root layers Pisum sativum
nitrate inhibits nodule initiation
reduced number of infections likely due to Psdella mutants develop less nodules Pisum sativum
cytokinins (CK) seems to be required for subsequent auxin accumulation during nodule organogenesis
CLE-RS2 works as negative regulator of nodule formation Lotus japonicus
discontinuity between rhizobia and plant cell walls was observed in proximal part of IZ and ZIII of mutant nodules Medicago truncatula
small and white nodules suggested malfunctioning nodules Medicago truncatula
(MIR166, MIR166G, AT5G63715) is involved in nodule development Medicago truncatula
mtr-miR396a promoter activity is primarily detected in nodule vascular tissues Medicago truncatula
mtr-miR396a promoter activity shows weak staining in nitrogen-fixing region (zone III) Medicago truncatula
(anac094, NAC094, AT5G39820) overexpression results in decreased red nodule numbers Lotus japonicus
nitrogen deficiency of ineffective symbiotic mutants induced increased number of nodules Medicago truncatula
nodules on roots of mutants transformed with modified NCRs did not show typical zonation of indeterminate nodules Medicago truncatula
MtGRF4 and MtGRF5 expression patterns partly overlap with miR396 expression pattern Medicago truncatula
nodulation-related CLE peptides may restrict nodulation Medicago truncatula
soybeans develop spherical, determinate nodules Glycine max
NF-YA/ (GCS1, HAP2, AT4G11720) and NF-YC/ (ATCCC1, CCC1, HAP5, AT1G30450) are required for nodule organogenesis
NOOT-BOP-COCH-LIKE (NBCL) functions are conserved in both indeterminate and determinate nodules
GRAS transcription factors (ATMLP-470, ATNSP1, NSP1, AT3G16400) and (ATNSP2, NSP2, AT2G33070) are required for rhizobia infection and nodule organogenesis Lotus japonicus; Medicago truncatula
indeterminate nodules possess nodule central meristem (NCM)
CO2 feeding may accelerate development of young nodules
Mtnf-ya1-1 mutant has 4.6-fold fewer nodules than A17 at 5 dpi Medicago truncatula
rate of nodulation and amount of nodule tissue per root showed no significant difference in three of the four combinations of plants and rhizobia tested Medicago; Sinorhizobium meliloti
WT nodules showed characteristic zonation of indeterminate nodules colonized with rhizobia Medicago truncatula
senescence and defence response-specific marker genes can be distinguished based on activation of defence-reactions and premature senescence-related autofluorescence Medicago truncatula
simultaneous knockdown of MtCLE12 and MtCLE13 enhanced number of nodules Medicago truncatula
ABA suppresses organogenesis at nodule development stage
increased microtubular cytoskeleton is observed in initial nodule primordium with dividing cells in rhizobium-infected roots
GmSPX5 overexpression significantly upregulates expression of GmASL2 Glycine max
phosphate (Pi) starvation inhibits nodulation in legume plants
mobile auxin signal coordinates infection with nodule organogenesis Medicago
MtMATE67 transcript levels are very low in wild-type roots before inoculation Medicago truncatula
GmINS1 RNA interference lines have 20.7% lower number of large nodules than empty vector control
GmINS1 suppression significantly inhibits nodule development
TE7 mutant is defective in IPD3 gene Medicago truncatula
DOES NOT MAKE INFECTIONS 2 (DMI2) / SYMBIOSIS RECEPTOR KINASE (SYMRK) kinase domain overexpression generates spontaneous nodules without rhizobia infection
ENOD40 npcRNA family is involved in formation of symbiotic nitrogen-fixing nodules
GmNF-YC4 overexpression increases nodule number Glycine max
mitotic reactivation of differentiated root cortex cells forms nodule primordium
MtKNOX3 and MtKNOX5 genes were unexpectedly upregulated in cluster #2 48 h after rhizobium inoculation Medicago truncatula
nodule apical meristematic cells differentiate into central symbiotic fate cells Medicago truncatula
scRNA-seq profiling with novel techniques provides wealth of data for understanding precise architecture of indeterminate nodules Medicago truncatula
linking high-resolution single-cell data with spatial information may be critical to answering questions about nodule development Medicago truncatula
SUPER NUMERIC NODULES (SUNN) functions in shoot regulation of nodule numbers Medicago truncatula
GmINS1 and GmEXPB2 double suppression lines have 38.2% reduction in surface area of 100 infection cells
nbcl mutants are characterized by emergence of root-like structures from the nodule vascular meristem (NVM)
untransformed roots of complemented plants produced only white nodules Medicago truncatula
transgenic composite soybean lines with double suppression of GmEXPB2 and GmINS1 severely inhibited soybean nodulation Glycine max
Chinese milk vetch (Astragalus sinicus) forms indeterminate-type N2-fixing root nodules Astragalus sinicus
sunn mutants display supernodulation phenotype Medicago truncatula
GmINS1 overexpression significantly affects nodule morphological development
NIN (NODULE INCEPTION) is essential for nodule organogenesis Lotus japonicus
NAC094-overexpressing plants (NAC-OE1 and NAC-OE2) exhibit increased nodule numbers Lotus japonicus
gibberellins (GA) are required for normal auxin activation during nodule primordia formation Pisum sativum
expression of a della dominant active protein induces spontaneous nodule-like structures Medicago truncatula
AsE246 is specific to nodulation Astragalus sinicus
MLD is vital for proper function of DMI2 regarding sufficient nodule development Medicago truncatula
GUS expression was not associated with nitrogen-fixation zone in 10 dpi nodules Medicago truncatula
GmEXPB2 and GmINS1 have distinctive divisions of functions in initiation and development of nodules Glycine max
EARLY NODULIN11 (ENOD11) is marker gene of early nodule development Medicago truncatula
stabilized DOES NOT MAKE INFECTIONS 2 (DMI2) initiates nodule development signaling Medicago truncatula
determinate nodules are derived from cell divisions in outer root cortex
GmINS1 RNA interference lines have 21.5% decrease in surface area of 100 infection cells
GmEXPB2 was most abundantly expressed in nodules at 7 days after inoculation Glycine max
DMI2/SYMRK kinase domain or full-length DMI2/SYMRK protein overexpression can induce spontaneous nodulation phenotype legume plants
roots expressing gDMI2-HAST versions with amino acid substitutions in MLD generate very few pink nodules Medicago truncatula
GmINS1 overexpression lines have 91.9% of nodules in large nodule group
DMI2 C39D point mutation results in no nodules Medicago truncatula
developmental gradient of cells forms invasion zone (II)
MtMATE67 transcript levels increase steadily after inoculation with rhizobia between 2 and 8 dpi rhizobia inoculation Medicago truncatula
GmINS1 overexpression lines have 20.9% higher dry weight of large nodules than empty vector control
Does Not fix Nitrogen 2 (MtDNF2) was upregulated in cluster #2 48 h after rhizobium inoculation Medicago truncatula
NP may serve as connections between more differentiated clusters Medicago truncatula
leghemoglobin binding and rapid delivery of oxygen contributes to low oxygen concentrations around rhizobia
INCREASING NODULE SIZE1 (GmINS1) overexpression results in increases in nodule biomass Glycine max
GmINS1 expression level is important contributor to the nodulation QTL Glycine max
legume plants growing in environments with abundant nitrogen do not make nodules despite the presence of rhizobia
double RNA interference of GmINS1 and GmEXPB2 significantly inhibits nodule development
induction of root cortical cell division establishes meristem and nodule primordium
three GmINS1 OX lines showed increases of 62.5%, 62.6%, and 66.9% in number of large nodules
GmINS1 expression is localized mainly within nodule cortex and parenchymatous cells Glycine max
GmINS1 might play dominant role in nodule enlargement Glycine max
GmEXPB2 and GmINS1 coordinately control soybean nodulation Glycine max
developmental gradient of cells forms senescence zone (IV)
GUS staining was observed in nodule primordium at 4 dpi Medicago truncatula
lipochitooligosaccharides (Nod factors) initiate nodule development
Lotus japonicus LjMATE1 is expressed in nodule-specific manner Lotus japonicus
wild-type plants showed 60.7% large nodules
suppression of GmINS1 reduced number of infection cells Glycine max
two β-expansin proteins (GmEXPB2 and GmINS1) might coordinately regulate soybean nodulation Glycine max
root identity is acquired during homeosis Lotus japonicus
GmEXPB2 transcripts are most abundant in early stages of nodule development Glycine max
developmental gradient of cells forms meristem (zone I)
GmINS1 expression is associated significantly with number of large nodules Glycine max
irregularly shaped infected cells stained deeply with toluidine blue had lost turgor pressure Lotus japonicus
(NLP4, AT1G20640) controls nodule number Lotus japonicus
indeterminate nodules consist of developmental gradient of cells forming distinct zones Medicago truncatula
nodules developed on empty vector-transformed WT roots showed typical zonation of indeterminate nodules with colonized cells in ZIII Medicago truncatula
Mtsym19 mutant develops slightly elongated white nodules with zonation Medicago truncatula
nodules may produce gibberellin (GA) Pisum sativum
apn1 mutants form small and dark brown or black nodules Lotus japonicus; Mesorhizobium loti
APN1 may play role(s) in nodule development even with compatible Mesorhizobium loti strains Lotus japonicus; Mesorhizobium loti
auxin transport inhibitors application is sufficient to induce nodulin genes Lotus japonicus
mtr-miR396b promoter activity is high in vascular tissues, infection zone (zone II) and upper parts of fixation zone (zone III) Medicago truncatula
extension of this part of nodules was observed in all mutants Medicago truncatula
nodule regions proximal to root corresponding to ZIII were devoid of bacteria Medicago truncatula
overaccumulated DOES NOT MAKE INFECTIONS 2 (DMI2) protein can activate nodule development signaling pathway without the presence of rhizobia
GmINS1 and GmEXPB2 double suppression lines have 33.4% decrease in individual nodule size
CK transported from the epidermis to the cortex promotes nodule organogenesis Medicago truncatula
MicroRNA 4407 (miR4407) is expressed in nodule primordia Glycine max
rhizobia-colonized cells were observed only in zones II and IZs of nodules formed on empty vector-transformed Mtsym19 and Mtsym20 roots Medicago truncatula
Psdella mutants display normal size and function nodules Pisum sativum
flavonoid biosynthesis plays important role as signaling molecules in nodule development Medicago truncatula
apn1 nodules developed infected cells filled with bacteroids Lotus japonicus
some infected cells of apn1 nodules at 8 dpi were swollen with irregularly shaped symbiosomes and lytic vacuoles Lotus japonicus
auxin signalling has recently been identified as regulator of rhizobia infection Medicago truncatula
LjNBCL1 functions in maintenance of determinate nodule identity Lotus japonicus
elongation zone is region of the root most susceptible to nodulation Medicago truncatula
heterotrimeric NF-Y complex regulates nodule differentiation Lotus japonicus; Medicago truncatula
NOOT-BOP-COCH-LIKE (NBCL) genes are required for maintaining the identity of indeterminate nitrogen-fixing nodules with persistent meristems
single-cell/nucleus analysis identifies responses within tissues and complex organs Medicago truncatula
biomass of individual nodules shows no differences between wild-type and Mtpin2 mutants after 3 weeks Medicago truncatula
Medtr8g037170 is MtMATE67 Medicago truncatula
suppression of GmINS1 limited nodule enlargement Glycine max
roots expressing gDMI2-HAST versions with amino acid substitutions in MLD are impaired in nodule development Medicago truncatula
mate67 mutant nodules were smaller than wild-type nodules from 10 dpi onwards Medicago truncatula
members of large family of NCR genes are activated in successive waves during nodule differentiation Medicago truncatula
CK produced in the epidermis may enhance nodule development in the cortex
excessive nodule development disturbs host growth
legume species form determinate nodules
GUS staining was detected within dividing cells of the nodule primordium Medicago truncatula
double suppression of GmEXPB2 and GmINS1 resulted in decreases in number and weight of large nodules Glycine max
indeterminate-type N2-fixing root nodules consist of gradient of developmental zones with persistent apical meristem (zone I), infection zone (zone II), and fixation zone (zone III) Astragalus sinicus
accumulated DOES NOT MAKE INFECTIONS 2 (DMI2) induces plant roots to start nodule development Medicago truncatula
protein level of DOES NOT MAKE INFECTIONS 2 (DMI2) / SYMBIOSIS RECEPTOR KINASE (SYMRK) is master determinate signal of nodule development
MtMATE67 transcripts have peak expression in invasion zone Medicago truncatula
soybeans produce determinate nodules Glycine max
GmINS1 functions primarily in nodule development Glycine max
34:3, 34:2, 36:5 and 36:4 PA accounts for increase in PA content in nodules Glycine max
actin and tubulin cytoskeleton-related gene expression change markedly during root–rhizobium interactions and nodule development Glycine max
GmINS1 acts in nodule development and expansion
Medicago truncatula plants silenced for ENOD40 form only a few and modified nodule-like structures Medicago truncatula
balance between ABA and Nod factor concentrations is important factor in nodulation
bacterial partner is delivered and released into symbiosomes within plant nodule cells
differentiation trajectory of these clusters consistent with well-known successive developmental process of symbiotic components Medicago truncatula
scRNA-seq profiling generates refined spatial and functional cellular map Medicago truncatula
miR1515 is involved in nodule development Glycine max
INCREASING NODULE SIZE1 (GmINS1) overexpression results in increases in nodule number Glycine max
GmEXPB2 and INCREASING NODULE SIZE1 (GmINS1) double suppression dramatically inhibits soybean nodulation Glycine max
GmINS1 functions especially during enlargement of nodules and infection cells Glycine max
nodule development signaling pathway activation without the presence of rhizobia leads to spontaneous nodulation phenotype
developmental gradient of cells forms nitrogen-fixation zone (III)
MtMATE67 transcript levels reach levels 15-fold higher than in 0 dpi roots 0 dpi roots Medicago truncatula
apical meristem of indeterminate nodules develops into continuous differentiated zones
marker genes of NF1 and NF2 indicates function along with appearance of nitrogen fixation zone Medicago truncatula
NP serves as connection Medicago truncatula
GmSACPD-A, GmSACPD-B, and GmSACPD-D mutants do not affect nodule development and structure
mutations in GmSACPD-A, GmSACPD-B, and GmSACPD-D increase seed stearic acid content without affecting nodule development Glycine max
high expression of GmSACPD-C in nodules is in agreement with observed cell senescence and necrotic cavity in the Gmsacpd-c mutants Glycine max
bacteria to infect the root tissue allows bacteria to reach developing nodule
actinorhizal nodules have peripheral infected tissue
indeterminate nodules maintain meristem throughout their life cycle Medicago truncatula
Zone 3 is fixation zone Medicago truncatula
GAs and (AtCKS, CKS, KDSB, AT1G53000) have antagonistic functions during nodule organogenesis Medicago truncatula
In mature nodules a senescence zone (zone IV) is established proximal to zone III Astragalus sinicus
MtMATE67 gene is induced early during nodule development Medicago truncatula
GmINS1 and GmEXPB2 double suppression lines have 14.7% fewer infection cells
nodule organogenesis incorporates nodule formation, differentiation, and maturation
stably transformed soybean plants with GmINS1 overexpression showed significant increases in individual nodule size Glycine max
Trx h in soybean roots is required during nodule development Glycine max
Pi starvation decreases total nodule fresh weight Glycine max
differentiation of nodule cells is one of primary processes involved in nodule development
Medicago truncatula root tip provides basis to explore nodule development and function Medicago truncatula
GmSACPD-C deleterious mutations result in nodule cell senescence Glycine max
tropical legume Sesbania rostrata has versatile nodulation features Sesbania rostrata
rapid reorganization of the actin cytoskeleton is observed in initial nodule primordium with dividing cells in rhizobium-infected roots
GmSPX5 overexpression significantly upregulates expression of GmASL3 Glycine max
GmSPX5 overexpression significantly upregulates expression of GmASL4 Glycine max
LjNF-YA1 has been implicated as regulator of nodulation Lotus japonicus
various cell types lead to creation of functional nodule capable of supporting nitrogen fixation
major disruption of iron, copper, or zinc delivery to nodules results in reduction in nodule size Medicago truncatula
one branched pathway of nodule developmental processes involves development of infection threads
GmNF-YC4 overexpression significantly upregulates expression of GmASL6 Glycine max
LjNF-YA1 was observed to participate in nodule formation by targeting genes encoding Short Internodes/stylish transcription factors ( (AtSTY1, SRS1, STY1, AT3G51060) (SRS2, STY2, AT4G36260) and STY3) Lotus japonicus
PLDα1 transcript levels change markedly during root–rhizobium interactions and nodule development Glycine max
34:2 and 36:2 PC and PE accounts for increase in PC and PE content in nodules Glycine max
GmNF-YC4 overexpression significantly upregulates expression of GmASL5 Glycine max
GmSPX5 interacts with GmNF-YC4 Glycine max
GmSPX5 overexpression significantly upregulates expression of GmASL5 Glycine max
Pi starvation inhibits soybean nodule biomass Glycine max
GmSPX5 positively regulates nodule fresh weight Glycine max
GmSPX5 and GmNF-YC4 control transcription of group of downstream genes in soybean nodules Glycine max
division of nodule cells is crucial for root nodule development
DNA methylation dynamics occurs during nodule development Medicago truncatula
NCR169 is essential for development of nitrogen-fixing nodules Medicago truncatula
GmSPX5–GmNF-YC4–GmASL6 regulatory pathway is present in soybean nodules
GmEXPB2 expression improves nodulation regardless of phosphorus availability Glycine max
various mutations of Gmsacpd-a, Gmsacpd-b, and Gmsacpd-d were analyzed for their effect on nitrogen-fixing nodules Glycine max
each type of nodule may show determinate growth
actinorhizal nodules differs structurally from legume nodules
Pi starvation decreases individual nodule fresh weight Glycine max
bi-directional, nodule-specific promoter located in an intron of the LjPLPIV gene generates nodule-specific antisense transcripts of the region encoding an N-terminal (ATSEC14, SEC14, AT4G39180) domain Lotus japonicus
differentiation of nodule cells is crucial for root nodule development
some Medicago truncatula Fix– mutants resemble Ljapn1 in nodule phenotypes Medicago truncatula; Lotus japonicus