| vitellin produced by cattle tick Boophilus microplus |
acts as |
elicitor of immune responses in sheep |
Boophilus microplus; Ovis aries |
| ARABIDOPSIS TOXICOS EN LEVADURA 31/6 |
resists |
overactivation of immune signaling |
Arabidopsis thaliana |
| perturbed lipid homeostasis in pi4kβ1,2 mutant |
is possibly causing |
autoimmunity in pi4kβ1,2 |
Arabidopsis thaliana |
| phosphorylation of (CPK28, AT5G66210) sites |
is required for |
(CPK28, AT5G66210) ubiquitination |
Arabidopsis thaliana |
| reactive oxygen species (ROS) |
function as signaling molecules to trigger |
additional immune responses |
|
| (AtTLP6, TLP6, AT1G47270) OE lines |
showed enhanced resistance in |
pathogen infection |
Arabidopsis thaliana |
| (ATPEP1, PEP1, PROPEP1, AT5G64900) expression |
is not affected by |
pathogen exposure |
Arabidopsis thaliana |
| AVRPM1A.1 isoforms EFRSD and ELGSD |
triggered |
HR when co-expressed individually with PM1A in N. benthamiana |
Nicotiana benthamiana |
| (ATBAK1, ATSERK3, BAK1, ELG, RKS10, SERK3, AT4G33430) and (ATFLS2, FLS2, AT5G63580) |
elaborate |
MTI response (MAMP-triggered immunity) |
|
| (CPK28, AT5G66210) phosphorylation of two E3 ligases |
induces |
(BIK1, AT2G39660) polyubiquitination |
Arabidopsis thaliana |
| Bg_9562 protein |
activates |
immune response |
Solanum lycopersicum |
| microbe-associated molecular patterns (MAMPs) |
include |
bacterial flagellin |
|
| (AtTLP6, TLP6, AT1G47270) overexpression lines |
phenocopy |
pi4kβ1,2 mutant phenotypes |
Arabidopsis thaliana |
| pi4kβ1,2 mutant |
phenocopies |
(AtTLP6, TLP6, AT1G47270) OE lines with regard to immunity |
Arabidopsis thaliana |
| RBOHD-produced reactive oxygen species (ROS) |
are thought to have |
antimicrobial activities |
Arabidopsis thaliana |
| BgTH12_06133_THUN-12 |
did not cause |
HR |
Nicotiana benthamiana |
| immunity to Pseudomonas syringae pv. maculicola ES4326 |
would have to be very sensitive to |
reduced pectin methylesterase (PME) activity |
Arabidopsis thaliana |
| LPS-triggered callose |
is significantly higher than |
flg22-triggered callose |
|
| context-dependent insect viruses |
enhances |
host resistance to pathogens |
|
| (AtTLP2, TLP2, AT2G18280) and (AtTLP6, TLP6, AT1G47270) |
are induced during |
infection |
Arabidopsis thaliana |
| loss of kinase activity independent of PI4K activity |
could lead to |
autoimmunity in pi4kβ1,2 |
Arabidopsis thaliana |
| Bg_9562 fragment 1 (18–51 aa) |
imparts |
disease tolerance |
Solanum lycopersicum |
| root immunity |
is not compromised in |
(ATTLP1, TLP1, AT4G24180) ,2,5,6,10 mutant, TLP6-DN OE lines, and PI4Kβ2 OE lines |
Arabidopsis thaliana |
| (CPK28, AT5G66210) phosphorylation of two E3 ligases |
induces |
immune response |
Arabidopsis thaliana |
| phosphorylation status of CALCIUM-DEPENDENT PROTEIN KINASE 28 (CPK28, AT5G66210) |
fine-tunes |
immune signaling regulation |
Arabidopsis thaliana |
| flg22-induced ROS production |
was prompted in |
NbAPX3-silenced leaves |
Nicotiana benthamiana |
| Pep3 expression |
is increased by |
pathogen exposure |
Arabidopsis thaliana |
| Pep3 expression |
is increased by |
Pseudomonas syringae infection |
Arabidopsis thaliana |
| phosphorylation of CALCIUM-DEPENDENT PROTEIN KINASE 28 (CPK28, AT5G66210) on Ser 318 |
activates |
(CPK28, AT5G66210) phosphorylation of two E3 ligases |
Arabidopsis thaliana |
| symbiotic viruses |
enhance |
insect host resistance to baculoviruses |
insect hosts |
| SERK3AB-silenced WT tomato |
are compromised in inducing immune response upon |
Bg_9562 protein or peptide 1 treatment |
Solanum lycopersicum |
| microbe-associated molecular patterns (MAMPs) |
include |
lipopolysaccharides |
|
| (ATCNGC2, CNGC2, DND1, AT5G15410) null mutant |
exhibits |
autoimmune phenotypes |
Arabidopsis thaliana |
| peptide 1 (Bg_9562 18–51 aa) |
imparts |
disease tolerance against R. solanacearum infection |
Solanum lycopersicum |
| Global metabolite profiling |
reinforced |
RPP1-like Ler R8-independent responses at a metabolic level |
Arabidopsis thaliana |
| LPS-triggered second long-lasting ROS burst |
was largely associated with |
chloroplasts |
Arabidopsis thaliana |
| 51526_3 and isoforms lacking alignments to BgTH12-06136 |
were proven or hypothesized to |
evade recognition |
Blumeria graminis f. sp. tritici |
| T3SS-mediated delivery of Bg_9562 |
is required for |
imparting immunity in tomato |
Solanum lycopersicum |
| SlMPK2 |
is activated upon stress responses caused by |
oligosaccharide elicitors |
Solanum lycopersicum |
| phosphorylation of CALCIUM-DEPENDENT PROTEIN KINASE 28 (CPK28, AT5G66210) on Thr 76 |
activates |
(CPK28, AT5G66210) phosphorylation of two E3 ligases |
Arabidopsis thaliana |
| SlMKK2 |
is |
key protein regulating immunity-associated programmed cell death |
Solanum lycopersicum |
| SlMPK3 |
is activated upon stress responses caused by |
oligosaccharide elicitors |
Solanum lycopersicum |
| LORE-mediated early ROS burst |
could not be detected in |
Nicotiana benthamiana, tomato, barley, or rice |
Nicotiana benthamiana; Solanum lycopersicum; Hordeum vulgare; Oryza sativa |
| MAMP-induced ROS burst |
is often very fast and produced in |
apoplast |
Arabidopsis thaliana |
| OsTCP21-Res plants |
accumulated H2O2 to significantly higher level than |
mock-treated plants |
Oryza sativa |
| (ATMAPK6, ATMPK6, MAPK6, MPK6, AT2G43790) |
is required for full elicitor-induced up-regulation of |
defense genes |
Arabidopsis thaliana |
| single and double anp mutants |
are defective in defense responses to |
oligogalacturonides (OGs) |
Arabidopsis thaliana |
| first ROS burst |
reflects |
MAMP-triggered ROS production |
|
| disruption of JA signaling |
led to |
reduced defense responses |
Oryza sativa |
| jasmonate (JA) / abscisic acid (ABA) branch |
contributes to induction of PME activity by |
Pseudomonas syringae pv. maculicola ES4326 |
Arabidopsis thaliana |
| OsrbohE and (ATARCA, AtRACK1, RACK1A, RACK1A_AT, RACK1z, SAC53, AT1G18080) genes |
were up-regulated in |
Ami-Ghd7 plants |
Oryza sativa |
| (ATMYC2, JAI1, JIN1, MYC2, RD22BP1, ZBF1, AT1G32640) single mutants |
had reduced |
pectin methylesterase (PME) activity |
Arabidopsis thaliana |
| (PME12, AT2G26440) mutants |
displayed increased |
Pseudomonas syringae pv. maculicola ES4326-induced pectin methylesterase (PME) activity |
Arabidopsis thaliana |
| Rpa1 (Resistance to Pseudomonas syringae pv. actinidiae 1) |
is |
nucleotide-binding leucine-rich repeat protein with N-terminal coiled-coil domain |
Nicotiana tabacum |
| AvrRpm1 Psa |
co-immunoprecipitates with |
RPA1 |
Nicotiana tabacum; Nicotiana benthamiana |
| RPA1 |
inhibits |
Psa growth |
Nicotiana tabacum |
| protein-protein interactions between translocated pathogen effectors and host proteins |
may be important for |
effector recognition and R protein activation |
|
| RPA1 |
also responds to |
avrRpm1 Psy from Pseudomonas syringae pv. syringae B728a (Psy) |
Nicotiana tabacum |
| mutation of one or two residues |
can enhance |
resistance |
|
| SA (salicylic acid) |
accumulates in |
Ler/ (ATKAS2, FAB1, KAS2, AT1G74960) NIL |
Arabidopsis thaliana |
| LPS |
could trigger |
intracellular ROS burst that is probably generated in the chloroplasts |
|
| redundant LPS recognition mechanism, in addition to (LORE, SD1-29, AT1G61380) |
functions to trigger |
second ROS burst |
Arabidopsis thaliana |
| reverse phenotype |
was also |
observed |
|
| conditional triple anp mutants |
are defective in defense responses to |
oligogalacturonides (OGs) |
Arabidopsis thaliana |
| some MAMPs |
can trigger |
chloroplast ROS burst |
|
| various chemicals |
were tested to slow down |
immune responses |
Nicotiana tabacum |
| Chaouch et al. |
did not detect |
any difference in SA accumulation in the (ATRBOHD, DELT1, RBOHD, AT5G47910) mutant compared with wild-type Arabidopsis |
Arabidopsis thaliana |
| SA (salicylic acid) |
causes up-regulation of |
some RPP1-like genes |
Arabidopsis thaliana |
| LPS-triggered second ROS burst |
was observed in |
all these plant species |
Nicotiana benthamiana; Solanum lycopersicum; Hordeum vulgare; Oryza sativa; Glycine max |
| core oligosaccharides |
induced |
early but relatively weak up-regulation of gene expression at ∼12 h after treatment |
Arabidopsis thaliana |
| Rx1-induced virus resistance and cell death response |
might indeed be |
distinct responses |
|
| LPS-triggered first transient ROS burst |
is similar to |
that induced by other MAMPs |
Arabidopsis thaliana |
| lipid A |
is largely responsible for |
intracellular ROS burst |
|
| These changes in the sulki1 mutants |
might be linked to |
RPP1-like Ler R8-independent transcriptional defense activation |
Arabidopsis thaliana |
| LPS pretreatment |
showed stronger restriction than |
flg22 pretreatment |
|
| core oligosaccharide and lipid A from Xanthomonas campestris |
can induce |
(AtCAPE9, ATPR1, PR 1, PR1, AT2G14610) and (AtBG2, AtPR2, BG2, BGL2, GNS2, PR-2, PR2, AT3G57260) expression |
Arabidopsis thaliana |
| wild-type cv Kongyu 131 infected with Guy11 |
accumulated high levels of H2O2 |
H2O2 accumulation |
Oryza sativa; Magnaporthe oryzae |
| genes associated with lesion greenness |
are enriched in |
activation of the immune system |
Arabidopsis thaliana |
| necrotic spots accompanying response |
occur only when |
resistance is less efficient |
|
| core oligosaccharides |
may play a role in |
intracellular ROS burst |
|
| miR319b-OE plants |
showed no measurable H2O2 accumulation in |
mock- or Guy11-infected rice |
Oryza sativa; Magnaporthe oryzae |
| ethylene response factor 1 (AtERF#092, ERF1, ERF1B, AT3G23240) overexpression line -1 |
showed higher induced levels of PME activity in response to |
either pathogen |
Arabidopsis thaliana |
| (ATMYC2, JAI1, JIN1, MYC2, RD22BP1, ZBF1, AT1G32640) (MYC3, AT5G46760) (MYC4, AT4G17880) triple mutants |
had reduced PME activity after |
Pseudomonas syringae pv. maculicola ES4326 infection |
Arabidopsis thaliana |
| single and double anp mutants |
are defective in defense responses to |
elf18 |
Arabidopsis thaliana |
| LPS |
induced |
second persistent elevation of ROS in the ensuing 4 to 24 h |
|
| (LORE, SD1-29, AT1G61380) |
is required for |
LPS-triggered first transient ROS burst |
Arabidopsis thaliana |
| plant |
needs to |
block pathogen multiplication and spread |
|
| D502V mutation in the IHD motif |
causes |
constitutive immune response |
Nicotiana benthamiana |
| proteins containing LRR domain |
are involved in |
pathogen defense |
|
| coding sequences of the five alleles of AvrPm1a.1 and of the three most abundant alleles of Bgt-51526 |
were evaluated for ability to trigger |
hypersensitive response (HR) when co-infiltrated with Pm1a into N. benthamiana |
Nicotiana benthamiana |
| mutations in (ATEDS1, EDS1, AT3G48090) |
can suppress |
enhanced resistance phenotypes of pi4kβ1,2 |
Arabidopsis thaliana |
| SA |
regulates |
RBOHD-dependent ROS production |
Arabidopsis thaliana |
| Rx1-NLS |
phenotype resembles |
autoimmune phenotype |
Nicotiana benthamiana |
| (ATEXO70H4, EXO70H4, AT3G09520) protein |
appears in nontrichome cells upon |
bacterial elicitor treatment |
Arabidopsis thaliana |
| flagellin-triggered rapid ROS burst |
is mediated by |
plasma membrane-localized NADPH oxidases |
Arabidopsis thaliana |
| miRNAs |
are associated with |
rice stripe virus (RSV) immune response |
Oryza sativa |
| Rpa1-like alleles from Nicotiana tabacum and N. benthamiana |
do not instigate |
host responses |
Nicotiana benthamiana |
| wild-type Rpa1 expression |
significantly restricted |
growth of PtoΔQ + A |
Nicotiana benthamiana; Pseudomonas syringae pv. tomato |
| cell death zone and surrounding tissue |
shows spatiotemporal regulation of |
immune response |
Solanum tuberosum |
| miRNAs |
are associated with |
Magnaporthe oryzae immune response |
Oryza sativa |
| (AtC3H66, TZF9, AT5G58620) mutant |
was infiltrated with |
1 µm flg22 |
Arabidopsis thaliana |
| same condition (5 mM EGTA) |
was applied to |
AvrRpm1 Psa screen |
Nicotiana tabacum |
| substitution of two amino acids in (ARC2, CH-CPN60A, CPN60A, Cpn60alpha1, CPNA1, SLP, AT2G28000) domain of PM3F |
was sufficient to expand |
recognition spectrum of PM3F |
Triticum aestivum |
| some residue exchanges |
enhancing |
immune response |
Triticum aestivum |
| dephosphorylation and inactivation of PM H+ -ATPase |
is consistent with |
alkalinization response of plant cell cultures to various PAMPs |
Arabidopsis thaliana |
| plant resistance to Botrytis cinerea |
was impaired by repressing |
auxin signalling |
|
| PB functions |
are linked to |
plant immunity |
|
| concentration of SA in transgenic plants with silenced (ATRBOHD, DELT1, RBOHD, AT5G47910) |
did not differ significantly from |
SA concentration in NT plants at the site of viral foci |
Solanum tuberosum |
| rice (Oryza sativa) / Magnaporthe system of Pikp / AVR-Pik |
demonstrates |
direct NLR–AVR interaction |
Oryza sativa |
| mislocalized receptors |
exert reduced sensitivity allowing |
higher level of CP permitted before HR induction |
Nicotiana benthamiana |
| pathogen infection |
triggers |
biosynthesis of SA, ET and JA |
|
| (AtTN10, TIR, TN10, AT1G72930) (Toll/interlukin-1 receptor) domains |
are featured in proteins associated with |
immune functions |
|
| miRNAs |
are associated with |
Xanthomonas oryzae pv. oryzae (Xoo) immune response |
Oryza sativa |
| miRNAs |
are associated with |
rice immune responses against Xoo |
Oryza sativa |
| suppression of auxin response pathway |
enhanced susceptibility to |
Phytophthora cinnamomi |
|
| RPA1 reaction pathway |
does not depend on |
NbRIN4 |
Nicotiana benthamiana |
| AvrRpm1 Psa |
is pulled down by |
AcRIN4_3 (PSS14094.1) |
Actinidia chinensis |
| plants |
have evolved |
immune receptors |
|
| powdery mildew resistance (Pm) genes |
can encode |
resistance against (BGT, GCN5, HAC3, HAG01, HAG1, HAT1, AT3G54610) |
Triticum aestivum |
| heterogeneity in plant responses to infection |
exists due to |
host immune sensitivity |
|
| OsACS1 and OsACS2 inducible overexpression |
significantly enhanced |
host resistance to rice blast |
Oryza sativa |
| auxin |
plays different or even opposing regulatory roles in |
plant immunity |
|
| decrease in cell-to-cell connectivity via plasmodesmata |
occurs in the presence of |
chitin |
Arabidopsis thaliana |
| PtoΔQ + A |
triggered |
immune reaction |
Nicotiana benthamiana |
| jasmonic acid (JA) exogenous application |
could enhance |
rice blast resistance |
Oryza sativa |
| RPA1 co-expressed with (AtRIN4, RIN4, AT3G25070) T166D |
does not show |
comparable response to (RPM1, RPS3, AT3G07040) and (AtRIN4, RIN4, AT3G25070) T166D co-expression |
Nicotiana benthamiana |
| UDP-glucosyltransferase (UGT76D1, AT2G26480) |
was identified as |
component of the feedback activation loop of SA biosynthesis |
|
| molecular evidence for the premise that positive regulators act at the HR site and negative regulators act in the surrounding areas |
is mostly lacking through |
lack of functional zonation studies |
|
| two polymorphic residues in PM3E |
are sufficient to confer |
resistance |
Triticum aestivum |
| (FOC, MIR160, MIR160A, AT2G39175) and (MIR398B, AT5G14545) overexpression |
enhanced |
rice blast resistance |
Oryza sativa |
| AvrRpm1 Psa |
is pulled down by |
(AtRIN4, RIN4, AT3G25070) |
Arabidopsis thaliana |
| Rx1-NLS |
appears to trigger |
autoimmune response resulting in stunted and/or non-viable plants |
Nicotiana benthamiana |
| no CP106 AVR protein detected in Rx1 plants in presence of p38 |
indicates that |
p38 did not inhibit Rx1 function |
Nicotiana benthamiana |
| RPA1:10xMyc |
does not pull down |
AvrRpm1 Pma:HA |
Nicotiana benthamiana |
| some effectors |
trigger immune responses in |
Nicotiana tabacum |
Nicotiana tabacum; Nicotiana benthamiana |
| SA |
was shown to be required for |
generation of mitochondrial ROS during pathogen infection |
|
| SA biosynthesis |
is not controlled by |
RBOHD-generated ROS |
Solanum tuberosum |
| AvrPm3 d3 |
is identified for |
different Pm3 alleles |
Triticum aestivum |
| several point mutants with enhanced NLR activity |
also have |
broader recognition spectrum |
Triticum aestivum |
| expression of P19 |
apparently did not block |
Rx1-mediated translational arrest of CP106 AVR |
Nicotiana benthamiana |
| nucleotide binding-leucine rich repeat (NB-LRR) proteins |
may activate immune responses in |
multiple parts of the cell |
|
| bioactive signalling intermediates |
promote |
resistance |
|
| miRNAs |
are associated with |
rice immune responses against RRSV |
Oryza sativa |
| AvrRpm1 Psa |
may activate |
a separate R gene RPA1 with a different biochemical mechanism |
|
| redox potential changes |
in both |
PTI and ETI |
Solanum tuberosum |
| PM3A-β1, -γ2, -γ7, -γ13, and -δ5 |
strongly increased |
response intensity |
Nicotiana benthamiana |
| AvrRpm1 Psa and RPA1 co-expression |
results in disappearance of |
both AvrRpm1 Psa and RPA1 proteins |
Nicotiana benthamiana |
| tight spatial regulation of immune processes |
is of utmost importance for |
efficient immunity |
|
| DQ2.5-Glia-α3 T-cell epitope |
is |
least toxic of the three epitopes |
Triticum aestivum; Aegilops tauschii |
| downstream immunity cascades |
frequently end in |
cell death |
|
| elf18 |
induces |
defense-related gene expression |
Arabidopsis thaliana |
| miR393 |
participates in immunity by inhibiting |
auxin signalling |
Arabidopsis thaliana; Oryza sativa |
| RPA1 |
co-immunoprecipitates with |
(AtRIN4, RIN4, AT3G25070) (RPM1-interacting protein 4) |
Nicotiana tabacum; Nicotiana benthamiana |
| pathogen growth |
is restricted when |
AvrRpm1 Psa is responded by RPA1 |
|
| (ATRBOHD, DELT1, RBOHD, AT5G47910) and SA |
regulate in |
spatiodiverse manner |
Solanum tuberosum |
| AvrRpm1 Psa |
physically associates with |
all (AtRIN4, RIN4, AT3G25070) homologues in different plant species |
Nicotiana benthamiana; Arabidopsis thaliana; Actinidia chinensis |
| non-functional Rpa1 K206A expression |
shows no comparable growth restriction of |
PtoΔQ + A |
Nicotiana benthamiana; Pseudomonas syringae pv. tomato |
| AvrRpm1 Psy-triggered response |
is possibly mediated by |
separate R gene in snap bean |
snap bean |
| oxidative burst |
is generated mostly by |
RBOH proteins and cell wall peroxidases |
|
| Rx1 immune activation |
prevents |
accumulation of CP106 AVR even though CP106 AVR transgene is transcribed and resulting mature mRNA appears intact |
Nicotiana benthamiana |
| miRNAs |
are associated with |
rice immune responses against pathogens |
Oryza sativa |
| Rpa1 gene |
is required for |
AvrRpm1 Psa-triggered immune response |
Nicotiana tabacum |
| AvrRpm1 (AHA1, HA1, OST2, PMA, AT2G18960) co-expressed with (AtRIN4, RIN4, AT3G25070) (RPM1, RPS3, AT3G07040) |
results in |
HR |
Nicotiana benthamiana |
| ultrastructural features in and surrounding the site of viral entry |
rendering |
immune response ineffective |
Solanum tuberosum |
| (ATRBOHD, DELT1, RBOHD, AT5G47910) |
confirms the existence of |
complex regulatory feedback loops |
Solanum tuberosum |
| resistance or immune receptor proteins |
are encoded by |
resistance (R) genes |
|
| auxin homeostasis |
participates in |
regulation of plant immunity |
Oryza sativa |
| one polymorphic residue shared by PM3B and PM3C |
is sufficient to convert |
PM3CS to a functional immune receptor |
Triticum aestivum |
| NbRIN4 suppresses |
suppresses |
(RPS2, uS2C, ATCG00160) activity |
Nicotiana benthamiana |
| SA-deficient line |
shows loss of spatiotemporal regulation in |
some genes |
Solanum tuberosum |
| Rx1 confers extreme resistance to virus without HR |
transient expression of CP in presence of immune receptor results in |
cell death visible as tissue necrosis |
Nicotiana benthamiana |
| detection of pathogen infection by cell surface and intracellular receptors |
activates |
processing and secretion of phytocytokines |
|
| OsPAL1-7 mRNA accumulation |
leads to |
enhanced immunity |
|
| elf18 |
induces |
growth inhibition of Arabidopsis seedling |
Arabidopsis thaliana |
| AvrRpm1 Psa |
co-immunoprecipitates with |
(AtRIN4, RIN4, AT3G25070) (RPM1-interacting protein 4) |
Nicotiana tabacum; Nicotiana benthamiana |
| AvrRpm1 (AHA1, HA1, OST2, PMA, AT2G18960) |
does not result in significant response in |
Nicotiana species without (RPM1, RPS3, AT3G07040) |
Nicotiana species; Pseudomonas syringae pv. maculicola |
| RPA1:10xMyc, AvrRpm1 Psa:HA, and FLAG:NbRIN4 three-component co-immunoprecipitation |
shows all three proteins are associated with one another in |
multicomponent protein complex |
Nicotiana benthamiana |
| wheat / mildew pathosystem |
demonstrates |
importance of single residues for NLR function |
Triticum aestivum |
| transcript levels of pathogenesis-related 1 (AtCAPE9, ATPR1, PR 1, PR1, AT2G14610) |
are induced after |
Rx1 activation |
Nicotiana benthamiana |
| flagellin perception |
induces |
expression of defense-related genes |
Arabidopsis thaliana |
| miRNAs |
are associated with |
Rice ragged stunt virus (RRSV) immune response |
Oryza sativa |
| AvrRpm1 (AHA1, HA1, OST2, PMA, AT2G18960) co-delivered with RPA1 |
does not trigger |
comparable response |
Nicotiana benthamiana |
| Psa growth |
was inhibited by |
RPA1 |
Nicotiana tabacum; Pseudomonas syringae pv. actinidiae |
| coeliac disease (CD) |
is |
one of the best understood food intolerances with regard to human immunology and T-cell specificity |
|
| biosynthesis of SA, ET and JA |
leads to |
activation of downstream signaling in cells producing them |
|
| fungal cytokinin (CK) biosynthesis |
is linked to |
rice immunity |
Magnaporthe oryzae; Oryza sativa |
| Pseudomonas syringae pv. maculicola ES4326 |
greatly induces |
pectin methylesterase (PME) activity |
Arabidopsis thaliana |
| LPS recognition system, in addition to (LORE, SD1-29, AT1G61380) |
mediates |
second cytoplasmically localized ROS response to LPS elicitation |
|
| LPS |
triggered |
two successive ROS bursts at distinct cellular locations |
Arabidopsis thaliana |
| wheat consumption |
may cause |
allergies and intolerances |
|
| Rx1 variants permit CP protein to accumulate to readily detectable levels before activating HR |
suggests that they are |
less effective in mounting immune response as they cannot suppress CP production |
Nicotiana benthamiana |
| miRNAs |
are associated with |
rice immune responses against RSV |
Oryza sativa |
| AvrRpm1 Psa-RPA1 association |
is |
specific |
Nicotiana benthamiana |
| immune response leading to the growth inhibition of the pathogen |
was mediated by |
endogenous Rpa1 |
Nicotiana tabacum |
| second, high-amplitude and sustained phase of ROS generation |
depends on |
ROS generation in multiple compartments |
|
| groups of polymorphic residues in different regions in PM3A LRR domain |
contribute to NLR function in different ways |
NLR function |
Triticum aestivum |
| reducing reactive oxygen species (ROS) expression in cells past a certain threshold |
can adversely modulate |
immunity |
|
| auto-activation of (BAL, SNC1, AT4G16890) |
does not cause |
spontaneous cell death in (BAL, SNC1, AT4G16890) mutant |
Arabidopsis thaliana |
| (BAL, SNC1, AT4G16890) |
is |
nucleocytoplasmic Toll-Interleukin Receptor (AtTN10, TIR, TN10, AT1G72930) -type NLR (TNL) protein |
Arabidopsis thaliana |
| chitin |
blocks |
pathogen invasion |
|
| transcriptional responses in pPCD |
have to be rapid and direct to |
counteract pathogen attack |
|
| elevated immune responses towards Magnaporthe oryzae strains lacking (CKS1, CKS1AT, AT2G27960) |
explain |
reduced tissue colonization |
Magnaporthe oryzae; Oryza sativa |
| growth-defence trade-off |
has been described in |
pathogen treatment and hyper-immune plants |
|
| (RPS4, uS4M, ATMG00290) |
confers resistance to |
Pseudomonas syringae pv. tomato strain DC3000 expressing AvrRps4 effector |
|
| immunogenic patterns |
trigger |
plant defenses |
|
| siR109944 |
interferes with |
plant immunity |
Oryza sativa; Arabidopsis thaliana |
| other genes |
show different response in |
SA-deficient line |
Solanum tuberosum |
| role of RBOH proteins as the principal generator of ROS after pathogen attack |
was also studied in |
symbiotic interaction with rhizobia |
|
| mutations in LRR domain |
affected |
AVR recognition |
|
| detailed information about involved residues |
can be used to expand |
recognition spectrum |
|
| nuclear pool of (BAL, SNC1, AT4G16890) |
is essential for |
autoimmune phenotype of (BAL, SNC1, AT4G16890) plants |
Arabidopsis thaliana |
| detection of pathogen infection by cell surface and intracellular receptors |
activates |
production of reactive oxygen species (ROS) by RESPIRATORY BURST OXIDASE HOMOLOGs (RBOHs) |
|
| (GH3.1, AT2G14960) constitutive expression |
reduced auxin content and enhanced |
defence response |
Oryza sativa |
| phosphorylation of T166 in (AtRIN4, RIN4, AT3G25070) |
for |
RPM1-mediated response |
|
| Pm3 locus |
provides |
17 functional alleles |
Triticum aestivum |
| PM3A-δ1 |
showed HR with |
all five AVR variants |
Nicotiana benthamiana |
| CP from dexamethasone-inducible promoter |
expressed in presence of different Rx1 localization variants allows monitoring of |
immune outputs such as HR development |
Nicotiana benthamiana |
| plant NLR proteins |
perceive |
pathogen-secreted virulence factors (effectors) |
|
| activation of immune response |
starts with |
recognition of immunogenic signals by cell surface and intracellular immune receptors |
|
| stromules |
might provide driving force to rapidly move chloroplasts toward |
nucleus |
|
| pentameric LT-B protein |
is |
a potent antigen |
Escherichia coli |
| complex immune system |
functions for |
pathogen perception |
|
| plant cells |
produce |
immunomodulatory peptides known as phytocytokines |
|
| cytokinins |
modulate |
plant immunity |
|
| ACCELERATED CELL DEATH 6 ( (ACD6, DEG16, AT4G14400) ) |
had |
highest fold change in ++B versus Ctrl in Ribo-seq among immune-response genes |
Arabidopsis thaliana |
| effector-triggered immunity (ETI) |
leads to induction of |
programmed cell death (PCD) |
|
| flagellin perception |
induces |
production of reactive oxygen species (ROS) |
Arabidopsis thaliana |
| ET biosynthesis inhibitor application |
could affect |
rice blast disease resistance |
Oryza sativa |
| RPA1 immunoprecipitated |
pulls down |
AvrRpm1 Psa and NbRIN4 |
Nicotiana benthamiana |
| XopL of Xanthomonas campestris pv. vesicatoria (Xcv) |
interfere with |
host immunity |
Xanthomonas campestris pv. vesicatoria |
| pathogen-induced ROS |
can be produced in |
mitochondria, chloroplasts and peroxisomes |
|
| some groups of polymorphic residues |
enable |
recognition of AVR |
Triticum aestivum |
| β-glucan perception by EXOPOLYSACCHARIDE RECEPTOR 3 (Lj EPR3) |
is not involved in |
immunity signaling |
Lotus japonicus |
| ABA |
acts as |
pro-inflammatory cytokine in human granulocytes |
Homo sapiens |
| tryptophan metabolism |
is responsible for controlling |
fungal load |
|
| no other importin-α single-mutant |
is not compromised in |
basal disease resistance |
Arabidopsis thaliana |
| comparative transcriptional profiling |
revealed |
core set of 312 DEGs common to defined HAMP and DAMP immune responses |
Zea mays |
| nitrogen limitation |
does not correlate with |
defence |
|
| immune receptors |
trigger |
effective immune response |
|
| VIGS (virus-induced gene silencing) |
applied to identify |
TIR-NLR gene responding to bacterial effector XopQ1 |
Nicotiana benthamiana |
| redox potential changes |
one of the first responses to |
pathogen recognition |
Solanum tuberosum |
| hypersensitive cell death response (HR) |
deprives |
pathogen of its nutrient source |
|
| polymorphisms of one or two residues in AVR-Pik |
were sufficient to disrupt |
direct interaction with receptor |
Oryza sativa |
| effector-triggered immunity (ETI) |
is commonly associated with |
hypersensitive cell death response (HR) at the infection site |
|
| mutant and multi-scale analyses |
identify |
highly unstable immune response mRNAs |
Arabidopsis thaliana |
| hypersensitive cell death response (HR) |
restricts |
pathogen spread |
|
| cpr6-1 mutant |
has |
immunity levels |
Arabidopsis thaliana |
| resistome |
encodes |
nucleotide-binding leucine-rich repeat (NLR) proteins |
|
| adaptive response to pathogen exposure |
elevates |
B cell counts |
Homo sapiens |
| pattern recognition receptors (PRRs) |
recognize |
pathogen-associated molecular patterns (PAMPs) |
|
| celastrol |
inhibits |
inflammation |
|
| immune-response genes |
had |
highest number of genes among GO terms enriched in genes with changes in RNA-seq and TE |
Arabidopsis thaliana |
| CK-induced immunity |
explains |
higher susceptibility of ahk mutants to Hyaloperonospora arabidopsidis |
|
| secretory trafficking pathway |
is involved in |
execution of defence responses |
|
| bacterial endotoxin challenge |
triggers damage in |
lymphatic and liver tissue |
Mus musculus |
| chloroplast-localized (ATGPX7, GPX7, GPXL7, AT4G31870) |
is important for |
immune responses |
Arabidopsis thaliana |
| (ATEDS1, EDS1, AT3G48090) |
functions upstream of |
RPS4-induced transcriptional reprogramming of the nucleus |
|
| salicylic acid (SA) |
is |
one of the three major defense hormones |
|
| race-specific resistance genes |
encode |
diverse types of proteins |
|
| extra- and intracellular plant receptors |
manipulate |
host immune pathways |
|
| calcium channel |
promotes |
immunity |
|
| plants |
deploy |
immune receptors |
|
| (ADR1, AT1G33560) |
functions downstream of |
other R genes |
|
| Hydrogen sulphide (H2S) |
participates in |
inflammation |
|
| autoimmune mutants |
reveal |
growth-defence trade-off paradigm is fundamentally incomplete |
|
| proteins in pollen coat of olive |
include |
allergens such as Ole e 1 and profilins |
Olea europaea |
| Calreticulin (CRT) |
appears to play a role in |
immune system |
|
| synthesis of callose |
occurs de novo as response to |
pathogen attack |
|
| Arabidopsis Nudix hydrolase 7 |
has been implicated in |
immunity |
Arabidopsis thaliana |
| allelic heterogeneity |
may be particularly common for |
genes involved in defense and immunity |
|
| mutations in (ATIMPALPHA3, IMPA-3, MOS6, AT4G02150) |
only partially suppress |
(BAL, SNC1, AT4G16890) autoimmunity |
Arabidopsis thaliana |
| (ATSTP4, STP4, AT3G19930) |
was induced by |
bacterial elicitors |
Arabidopsis thaliana |
| application of purified β-1,3-glucan |
is accompanied by accumulation of |
PR-proteins |
Triticum aestivum |
| NO and cGMP |
are implicated in |
pathogen defence |
|
| granulocytes |
produce |
several reactive oxygen species, including nitric oxide (NO) |
Homo sapiens |
| (ATWRKY6, WRKY6, AT1G62300) and (ATWRKY53, WRKY53, AT4G23810) |
were induced by |
OGs and Flg22 at 1 h |
|
| Arabidopsis type II metacaspases (MC4–9) |
have |
various roles in cell death and immunity |
Arabidopsis thaliana |
| (ATUCP2, PUMP2, UCP2, AT5G58970) protein levels |
increase in |
lung after lipopolysaccharide stimulation |
|
| vesicular body accumulation |
is |
actin-dependent process |
Arabidopsis thaliana |
| reactive oxygen species (ROS) and mitogen-activated protein kinases (MAPKs) |
result in |
programmed cell death |
|
| high expression of pathogen recognition receptor genes |
can lead to |
cell death and dwarf phenotypes |
|
| genes containing AAGTCAA motif |
are related to |
immune response |
Arabidopsis thaliana |
| abiotic stresses such as elevated temperatures |
have been known to severely cripple |
immunity |
|
| abscisic acid (ABA) |
acts as pro-inflammatory cytokine in |
granulocytes |
Homo sapiens |
| peptides |
are used for |
antigene processing |
Mammalia |
| (ATEDS1, EDS1, AT3G48090) |
functions after |
(RPS4, uS4M, ATMG00290) activation |
|
| EDS1-dependent genes |
were registered as |
strongly pathogen-induced in Ws-0 |
Arabidopsis thaliana |
| metchnikowin (Mtk) |
is |
immune inducible peptide |
Drosophila melanogaster |
| metchnikowin (Mtk) |
is |
proline-rich peptide |
Drosophila melanogaster |
| TLP knockout |
did not display reduced immunity against |
bacterial virulent pathogen Psm ES4326 |
Arabidopsis thaliana |
| nucleotide-binding and leucine-rich repeat receptors (NLRs) |
indirectly detect |
pathogen effectors |
|
| TLP knockout |
did not display reduced immunity against |
tested pathogens including oomycete Ha Noco2 |
Arabidopsis thaliana |
| TLPs' effect on PI4Kβ protein levels |
is mainly seen during |
initial time points after infection with Ha Emwa1 |
Arabidopsis thaliana |
| degradation of BOTRYTIS-INDUCED KINASE1 (BIK1, AT2G39660) |
regulates |
immune response |
Arabidopsis thaliana |
| selective regulation of packaging of mitochondrial protein into EVs |
prevents release of |
damaged components that would act as proinflammatory damage-associated molecular patterns |
Mammalia |
| WRKY |
plays an important role in regulating the expression of |
defence-responsive genes |
|
| regulatory interplay of autophagy and other membrane trafficking pathways |
remains obscure in |
programmed cell death and defence responses |
|
| plant hypersensitive response |
is thought to act against |
invading pathogens |
|
| peri-cell wall apposition (CWA) actin and microtubule networks |
can facilitate |
local organelle positioning |
Arabidopsis thaliana |
| commensal bacteria |
do not or only weakly induce responses in |
wild-type (WT) plants |
|
| (AtZAT6, C2H2, CZF2, ZAT6, AT5G04340) zinc finger proteins |
are required for |
pathogen defense |
Arabidopsis thaliana |
| ROS |
mediate responses to |
pathogen defence |
|
| harpin-elicited stomatal closure |
is important in |
plant immunity to bacterial invasion |
Nicotiana benthamiana |
| 18–51 aa residues of Bg_9562 |
is required for |
imparting immunity in tomato |
Solanum lycopersicum |
| (ATBAK1, ATSERK3, BAK1, ELG, RKS10, SERK3, AT4G33430) and (EVR, SOBIR1, AT2G31880) |
activate |
spontaneous immune responses |
Arabidopsis thaliana |
| Bg_9562 fragment 3 (18–103 aa) |
imparts |
disease tolerance |
Solanum lycopersicum |
| increasing PI4Kβ levels by overexpression or generating tlp KO or TLP DN OE lines |
does not suppress |
plant immunity |
Arabidopsis thaliana |
| reduced (BIP, BIP2, AT5G42020) accumulation in ER |
may have an effect on |
biogenesis of some proteins involved in HR PCD |
Nicotiana benthamiana |
| OsPR5 |
chitin-induced expression declined to 32.4–57.4% in |
OsCERK1 RNAi transgenic cell lines |
Oryza sativa |
| (RPS4, uS4M, ATMG00290) becoming activated through overexpression |
is consistent with |
dwarf phenotype with necrotic lesions and death |
Arabidopsis thaliana |
| PI4Kβ2 levels reduction |
coincides with |
time points after Ha infection when (AtTLP2, TLP2, AT2G18280) and (AtTLP6, TLP6, AT1G47270) are induced |
Arabidopsis thaliana |
| RESPIRATORY BURST OXIDASE HOMOLOG D (ATRBOHD, DELT1, RBOHD, AT5G47910) |
is essential for maintaining |
microbiota homeostasis |
Arabidopsis thaliana |
| (ATFLS2, FLS2, AT5G63580) promoter |
is responsive to |
biotic stresses |
|
| BnaMAPKKK genes |
are regulated by |
fungal pathogen treatments |
Brassica napus |
| mismatched pair of immune components |
triggers |
autoimmunity |
|
| vacuolar trafficking pathway |
is involved in |
execution of defence responses |
|
| mutation of the predicted catalytic residues of ENHANCED DISEASE SUSCEPTIBILITY1 (ATEDS1, EDS1, AT3G48090) and (ATPAD4, PAD4, AT3G52430) |
did not compromise |
their functions in effector-triggered immunity (ETI) or basal resistance responses |
Arabidopsis thaliana |
| (AtTN10, TIR, TN10, AT1G72930) domain |
is present in |
proteins involved in the immune response |
|
| polymorphism |
triggers |
autoimmunity |
Arabidopsis thaliana |
| MHA1L |
appears to be transcriptionally induced upon |
pathogen infection |
Arabidopsis thaliana |
| maintenance of hexamer |
is not required for |
autoimmunity |
Arabidopsis thaliana |
| (ATEDS1, EDS1, AT3G48090) |
blocks |
consequences of (RPS4, uS4M, ATMG00290) over accumulation in growth inhibition |
Arabidopsis thaliana |
| mutations in genes for (ATCAX3, ATHCX1, CAX1-LIKE, CAX3, AT3G51860) vacuolar H+/calcium transporter |
can cause |
autoimmunity |
Arabidopsis thaliana |
| FORMIN4 localization |
is stable and segregated from |
dynamic traffic of endosomal network |
Arabidopsis thaliana |
| fine spatial segregation of destinations |
is for |
actin-dependent immunity cargo |
Arabidopsis thaliana |
| plant actin cytoskeleton |
is critical for |
immune responses to bacteria |
Arabidopsis thaliana |
| reactive oxygen species (ROS) |
activating |
peach immune system |
Prunus persica |
| harpin |
is a bacterial PAMP that elicits |
VPE-dependent responses |
Nicotiana benthamiana |
| ACD6-Est-1 allele |
can cause |
autoimmunity |
Arabidopsis thaliana |
| such trafficking |
can be guided by |
molecules released at the site of pathogen contact |
Arabidopsis thaliana |
| FORMIN4 response |
can be induced in |
absence of specific fungal–disease promoting effectors |
Arabidopsis thaliana |
| pen3-1 mutant plants |
showed |
elevated level of haustoria formation beyond that of the formin triple mutant |
Arabidopsis thaliana |
| actin cytoskeleton |
is known to support |
cell wall apposition (CWA) function |
Arabidopsis thaliana |
| initial activation |
is likely to occur through |
detection of microbial and damage-associated molecular patterns (MAMPs and DAMPs) |
Arabidopsis thaliana |
| ERQC |
is required for |
PTI via regulation of biogenesis of pattern recognition receptor (EFR, AT5G20480) |
Arabidopsis thaliana |
| FORMIN4-GFP regions |
coincide with |
small callose deposits |
Arabidopsis thaliana |
| FORMIN4-GFP and FORMIN4(ΔFH1-FH2)-GFP fusion proteins |
are delivered to |
Blumeria graminis f. sp. hordei (Bgh) sites in the formin4/7/8 genetic background |
Arabidopsis thaliana; Blumeria graminis f. sp. hordei |
| rapid redirection of membrane traffic |
facilitates |
effective host defence |
|
| T2 lines with hybrid necrosis phenotype |
expressed |
(FMO1, AT1G19250) |
Arabidopsis thaliana |
| ROS production |
was significantly suppressed in |
OsCERK1 RNAi transgenic rice cell lines |
Oryza sativa |
| (PGN, AT1G56570) Xoo |
triggered |
ROS production |
Oryza sativa |
| callose deposition |
was dramatically reduced in |
OsCERK1 RNAi transgenic rice lines |
Oryza sativa |
| reactive oxygen species (ROS) |
are involved in |
pathogen responses |
|
| WRKY |
plays an important role in |
disease resistance |
|
| rboh silencing |
does not impair |
hypersensitive response |
Nicotiana benthamiana |
| late responses to pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs) |
are considerably different |
between the two classes of elicitors |
|
| strong early ROS burst |
could be induced in |
soybean after LPS treatment |
Glycine max |
| response of transgenic lines to pathogen challenge |
was analysed at different |
levels |
|
| loss of resistance but not cell death |
could be interpreted as |
quantitative difference in immune response |
|
| alpaca immunized with algal cell lysate |
produces |
high-titer antisera |
Lama pacos; Chlamydomonas reinhardtii |
| wheat prolamins |
cause |
celiac disease (CD) |
|
| α-gliadins |
are |
major triggers of celiac disease (CD) |
|
| eds1-1 |
had |
only 2/1 induced/repressed genes in response to Pst-AvrRps4 |
Arabidopsis thaliana |
| actin-mediated trafficking |
is apparent during |
hyphal invasion |
Arabidopsis thaliana |
| FORMIN4-GFP hypocotyl cells stained with aniline blue |
show |
deposits of callose |
Arabidopsis thaliana |
| pathogenic consequences of profilin oligomerization |
is involved in |
allergic responses |
Mammalia |
| factors involved in Pst DC3000-induced HR PCD |
may depend on |
(AtCRT3, CRT3, EBS2, PSL1, AT1G08450) (EBS1, PSL2, UGGT, AT1G71220) N-glycan decoration but not on BiPs |
Nicotiana benthamiana |
| (ATMYC2, JAI1, JIN1, MYC2, RD22BP1, ZBF1, AT1G32640) single mutants |
had reduced PME activity after |
Pseudomonas syringae pv. maculicola ES4326 infection |
Arabidopsis thaliana |
| (ATMYC2, JAI1, JIN1, MYC2, RD22BP1, ZBF1, AT1G32640) single mutants |
did not affect activity in |
Alternaria brassicicola-challenged plants |
Arabidopsis thaliana |
| AVRPM1A.1 isoforms KLGCD, KLGSD, and EFRSN |
did not trigger |
HR when co-expressed individually with PM1A in N. benthamiana |
Nicotiana benthamiana |
| (ATNPR3, NPR3, AT5G45110) |
is substrate of |
(AtUBP12, UBP12, AT5G06600) /13 |
Arabidopsis thaliana |
| microbe-associated molecular patterns (MAMPs) |
trigger |
costly defenses |
Arabidopsis thaliana |
| SENESCENCE-ASSOCIATED GENE101 (SAG101, AT5G14930) |
is |
(ANAC008, SOG1, AT1G25580) target gene |
Arabidopsis thaliana |
| MEDEA (EMB173, FIS1, MEA, SDG5, AT1G02580) |
involved in repression of |
immune responses |
Arabidopsis thaliana |
| receptor overexpression |
antagonizes |
colonization |
Arabidopsis thaliana |
| sog1-1 mutant |
showed significantly larger anthracnose lesion area than |
wild-type |
Arabidopsis thaliana |
| 129 genes with shared haplotypes |
were significantly enriched for |
genes involved in response to virus |
Arabidopsis thaliana; Arabidopsis halleri; Arabidopsis lyrata; Arabidopsis arenosa |
| npr4-4D |
blocks increased expression of |
(CBP60G, AT5G26920) |
Arabidopsis thaliana |
| (PAS2, PEP, PEPINO, AT5G10480) |
plays important role in |
disease resistance |
Arabidopsis thaliana |
| FORMIN4-GFP distribution |
is severely reduced and poorly targeted after |
cytochalasin E pre-treatment |
Arabidopsis thaliana |
| wild-type plants infected by Guy11 |
accumulated measurable levels of H2O2 |
H2O2 accumulation |
Oryza sativa; Magnaporthe oryzae |
| plant hypersensitive response |
is part of |
plant immune system |
|
| two ERD2-like genes and their putative ligands |
may regulate |
HR PCD |
Nicotiana benthamiana |
| cell wall appositions (CWAs) formation |
requires coordination with export of |
barrier material |
Arabidopsis thaliana |
| FORMIN4 deactivation |
partially compromises |
subsequent defense |
Arabidopsis thaliana |
| FORMIN4-GFP expression |
reduced |
presence of haustoria |
Arabidopsis thaliana |
| autophagy |
is implicated in |
basal immunity |
|
| plant actin dynamics |
are essential to |
cell wall apposition response |
Arabidopsis thaliana |
| FORMIN4-GFP transport |
occurs as |
broad-spectrum fungal-response mechanism |
Arabidopsis thaliana |
| actin cables |
exhibit |
transient interactions with the periphery of the cell wall apposition (CWA) |
Arabidopsis thaliana |
| studies of targeted (ATPEN3, PEN3, AT5G36150) transportation |
support |
hypothesis that initial activation occurs through detection of microbial and damage-associated molecular patterns (MAMPs and DAMPs) |
Arabidopsis thaliana |
| hydathode pores |
fail to fully close in response to |
immunogenic elicitors of bacterial origin |
|
| programmed cell death (PCD) |
is |
common host response to microbial infection |
|
| ERD2a/2b co-silencing |
exacerbated |
PCD induced by Xoo or Pst DC3000 and R gene-mediated PCD |
Nicotiana benthamiana |
| (BIP3, HSP70-13, AT1G09080) over-expression in rice |
reduces |
Xa21-mediated resistance |
Oryza sativa |
| MLO |
PGN-induced expression was significantly suppressed to 8.6–32.2% in |
OsCERK1 RNAi transgenic cell lines |
Oryza sativa |
| pathogen infection |
triggers |
down-regulation of NITROGEN LIMITATION ADAPTION (BAH1, NLA, SYG1, AT1G02860) expression |
Arabidopsis thaliana |
| most significant T-cell epitopes in patients with CD |
are |
PFPQPQLPY (DQ2.5-glia-α1a), PYPQPQLPY (DQ2.5-glia-α1b), PQPQLPYPQ (DQ2.5-glia-α2) and FRPQQPYPQ (DQ2.5-glia-α3) |
|
| positional feedback |
contributes to |
outcomes of pre-invasion defense |
Arabidopsis thaliana |
| molecular, genetic, or chemical interference of actin dynamics |
lowers |
penetration defense |
Arabidopsis thaliana |
| FORMIN4 gene |
is one of |
three actin-binding protein genes present within an established immunity expression cluster |
Arabidopsis thaliana |
| FORMIN4 |
is |
most frequently upregulated gene responsive to prokaryote, oomycete, and fungal stimuli |
Arabidopsis thaliana |
| FORMIN4-GFP stable transformants |
are infected with |
Magnaporthe oryzae |
Arabidopsis thaliana; Magnaporthe oryzae |
| alternative systems |
must be upstream in temporal sequence from |
actin binding proteins, such as FORMIN4, that are under tight expression control and embedded in the cargo membrane |
Arabidopsis thaliana |
| nup205-3 heterozygous plants from cross to wild-type |
had |
wild-type disease susceptibility phenotype |
Arabidopsis thaliana |
| plants without functional co-chaperone (ATRAR1, PBS2, RAR1, RPR2, AT5G51700) |
show lower accumulation of |
immune receptor (RPM1, RPS3, AT3G07040) |
|
| OsCERK1 |
indispensable for |
gene expression |
Oryza sativa |
| MODIFIER OF snc1-1 (MOS1, AT4G24680) |
modulates |
plant disease resistance |
Arabidopsis thaliana |
| (ATSNAK2, GRIK1, AT3G45240) (TAIR locus ) |
is |
virus-response gene with haplotypes shared across all four species |
Arabidopsis thaliana; Arabidopsis halleri; Arabidopsis lyrata; Arabidopsis arenosa |
| chitin-induced expression of defense genes |
was suppressed in |
OsRLCK176 RNAi transgenic rice lines |
Oryza sativa |
| fungal elicitors |
trigger |
up-regulation of MIR827 |
Arabidopsis thaliana |
| H2O2 accumulation |
is |
host response in wheat to infection by S. tritici |
Triticum aestivum |
| (EDS4, EMB3142, AT5G51200) |
shows |
enhanced disease susceptibility phenotype |
Arabidopsis thaliana |
| expression of ERD2a and (ERD2B, AT3G25040) |
was transiently up-regulated during |
Xoo-induced HR |
Nicotiana benthamiana |
| SUPPRESSOR OF GAMMA RESPONSE 1 (ANAC008, SOG1, AT1G25580) |
is required for |
resistance against the hemi-biotrophic fungus Colletotrichum higginsianum |
Arabidopsis thaliana |
| cell wall appositions (CWAs) formation |
requires controlled invagination of |
plasma membrane (PM) |
Arabidopsis thaliana |
| pathogen infection |
induces |
ER stress and (BIP, BIP2, AT5G42020) expression |
|
| protein secretion |
is involved in |
plant immunity |
|
| wild-type and lys12 mutant roots |
produce reactive oxygen species (ROS) after treatment with |
CO4, CO8, oligogalacturonides, laminarin, flagellin (flg22) |
Lotus japonicus |
| MODIFIER OF snc1-1 (MOS1, AT4G24680) |
binds to promoter of |
SUPRESSOR OF npr1-1 CONSTITUTIVE 1 (BAL, SNC1, AT4G16890) |
Arabidopsis thaliana |
| OXIDATIVE SIGNAL-INDUCIBLE1 (AGC2, AGC2-1, AtOXI1, OXI1, AT3G25250) |
is |
(ANAC008, SOG1, AT1G25580) target gene |
Arabidopsis thaliana |
| (AtWAK1, PRO25, WAK1, AT1G21250) (TAIR locus ) |
is |
virus-response gene with haplotypes shared across all four species |
Arabidopsis thaliana; Arabidopsis halleri; Arabidopsis lyrata; Arabidopsis arenosa |
| FORMIN4-GFP fusion product |
is found almost exclusively in |
locality of cell wall appositions (CWAs) formed in response to the fungus |
Arabidopsis thaliana |
| seedlings grown in half-strength MS media supplemented with 1% sucrose; 500 mg/L MES pH 5.7 and 0.8% phyto agar plates with high humidity for 9 days under short day conditions |
have leaves detached and incubated for |
30 min in 20 μM flg22 or control |
Arabidopsis thaliana |
| substantial transcriptional reprogramming |
confers |
disease resistance |
|
| weakened clock function upon infection |
may be necessary to allow |
continuous immunity to contain infectious bacteria and prevent re-infection |
Arabidopsis thaliana |
| (EDS4, EMB3142, AT5G51200) mutant |
was identified in |
screen for individuals more susceptible to infection with Pseudomonas syringae Psm ES4326 |
Arabidopsis thaliana |
| (AtNPF5.2, ATPTR3, NPF5.2, PTR3, AT5G46050) |
has function in |
pathogen defense |
Arabidopsis thaliana |
| translocated pathogen effectors |
physically associate with |
host proteins |
|
| significant host response |
led to |
inhibition of pathogen growth |
Nicotiana tabacum |
| role of RBOH proteins as the principal generator of ROS after pathogen attack |
was mostly studied in |
compatible interactions with bacterial and oomycete pathogens |
|
| single residues in NLR |
is important for |
NLR function |
|
| hairpin silencing construct hp39 |
blocks |
HR triggered by AvrRpm1 Psa |
Nicotiana tabacum |
| AvrRpm1 (PSY, AT5G17230) co-expressed with Rpa1 |
results in |
host response comparable with AvrRpm1 Psa-triggered HR |
Nicotiana benthamiana |
| (ATRBOHD, DELT1, RBOHD, AT5G47910) |
is involved in |
spatial control of SA accumulation |
Solanum tuberosum |
| avirulence protein (AVR) |
is encoded by |
avirulence gene (Avr) |
|
| rapid successful assembly of a focused cell wall apposition (CWA) |
prevents |
biotrophic haustorium formation |
Arabidopsis thaliana |
| FORMIN4(ΔFH1-FH2)-GFP deletion mutant |
is delivered to |
Blumeria graminis f. sp. hordei (Bgh) sites |
Arabidopsis thaliana; Blumeria graminis f. sp. hordei |
| MRK1, RAF26, and RAF39 |
have redundant roles in |
immune-triggered reactive oxygen species (ROS) production |
Arabidopsis thaliana |
| pme mutants more susceptible to Pseudomonas syringae pv. maculicola ES4326 |
did not show reduced |
pathogen-induced pectin methylesterase (PME) activity |
Arabidopsis thaliana |
| pattern recognition receptors (PRRs) |
leads to |
callose deposition |
|
| LORE-mediated apoplastic rapid ROS burst |
appears specific to |
Brassicaceae family of plants |
|
| elf18 |
induces |
rapid oxidative burst |
Arabidopsis thaliana |
| BAK1-dependent phosphorylation of (AtCERK1, AtLYK1, CERK1, LYK1, LYSM RLK1, AT3G21630) |
potentiates |
antifungal immunity |
Arabidopsis thaliana |
| Rpa1 isolated from Nicotiana tabacum under native 1.5 Kb promoter |
instigates |
AvrRpm1 Psa-triggered responses |
Nicotiana benthamiana |
| lowered sensitivity of immune receptor for cognate ligand viral CP |
could result in |
delayed induction of immune response allowing viral escape |
Nicotiana benthamiana |
| P38 |
did not inhibit |
Rx1-mediated translational arrest of CP106 AVR |
Nicotiana benthamiana |
| OX-dml lines |
display enrichment in biological functions such as |
immune response |
Populus tremula × Populus alba |
| Bg_9562 protein treatment |
provides immunity against |
R. solanacearum infection |
Solanum lycopersicum |
| tandem duplication events |
may have played important role in |
maintaining the immune system in oak trees |
Quercus dentata |
| poplar genes involved in immune response |
participate in |
ectomycorrhizal formation |
Populus tremula × Populus alba |
| professional phagocytes |
are source of most information on |
phagocytosis |
|
| TLP6-DN OE lines |
did not display reduced immunity against |
tested pathogens including oomycete Ha Noco2 |
Arabidopsis thaliana |
| (ATTLP1, TLP1, AT4G24180) ,2,5,6,10 mutant |
did not display reduced immunity against |
tested pathogens |
Arabidopsis thaliana |
| (YAO, AT4G05410) et al. (2021) |
show |
increase of overall Lys63 chain levels after flg22 treatment is dependent on (APP, PARP2, PP, AT4G02390) |
Arabidopsis thaliana |
| Resistosome containing ion-conducting pore |
penetrates into |
plasma membrane (PM) |
Arabidopsis thaliana |
| specific (PMES, AT4G10050) |
are responsible for |
plant immunity |
|
| Rice TLPs |
transcription is upregulated upon |
pathogen infection |
Oryza sativa |
| GO:0042742 (defense response to bacterium) |
was enriched in |
SOM8 |
Setaria viridis |
| PI4Kβ2 OE lines |
did not display reduced immunity against |
tested pathogens including oomycete Ha Noco2 |
Arabidopsis thaliana |
| microbe-associated molecular patterns (MAMPs) |
include |
fungal glucans |
|
| (CPK28, AT5G66210) ubiquitination and degradation |
is mediated by |
ARABIDOPSIS TOXICOS EN LEVADURA 31/6 |
Arabidopsis thaliana |
| RBOHD-produced reactive oxygen species (ROS) |
repress the expression of |
bacterial genes associated with the type II secretion system |
Arabidopsis thaliana |
| NEMATODE-INDUCED LRR-RLK1 (GRACE, NILR1, AT1G74360) |
is induced upon |
nematode infection |
|
| Bg_9562 |
induces |
host defense responses |
Solanum lycopersicum |
| microbe-associated molecular patterns (MAMPs) |
include |
fungal chitins |
|
| Leaves challenged with avirulent Pst. DC3000 (avrRpt2) |
harvested at |
48 hours post-inoculation (hpi) |
|
| Silencing of (AtRIN4, RIN4, AT3G25070) |
did not affect |
RPA1 activity |
Nicotiana tabacum |
| hp39_5 silencing construct |
is required for blocking |
AvrRpm1 Psa-triggered HR |
Nicotiana tabacum |
| (RPM1, RPS3, AT3G07040) |
does not respond to |
AvrRpm1 Psa or AvrRpm1 (PSY, AT5G17230) |
Nicotiana benthamiana |
| second, high-amplitude and sustained phase of ROS generation |
occurs |
a few hours after infection |
|
| ROS generation in multiple compartments |
includes |
apoplast, chloroplasts, mitochondria and peroxisomes |
|
| flax (Linum usitatissimum) / rust pathosystem |
demonstrates |
importance of single residues for NLR function |
Linum usitatissimum |
| AVRPM1A.2_1 and AVRPM1A.2_2 |
triggered |
Pm1a-dependent HR |
Nicotiana benthamiana |
| PI4Kβ2 OE lines |
did not display reduced immunity against |
bacterial virulent pathogen Psm ES4326 |
Arabidopsis thaliana |
| downregulation of (ATRBOHD, DELT1, RBOHD, AT5G47910) |
possibly contributes to maintaining |
balanced immune response |
Arabidopsis thaliana |
| (ATPEP1, PEP1, PROPEP1, AT5G64900) expression |
is not affected by |
PAMP (pathogen-associated molecular pattern) exposure |
Arabidopsis thaliana |
| RESPIRATORY BURST OXIDASE HOMOLOG D (ATRBOHD, DELT1, RBOHD, AT5G47910) |
plays a particularly crucial role in |
immunity |
Arabidopsis thaliana |
| dwarf and early senescence phenotype |
correlates with |
constitutive defense responses |
Arabidopsis thaliana |
| ubiquitination |
coordinates |
proteasomal and vacuolar degradation pathways |
|
| (AtCAPE9, ATPR1, PR 1, PR1, AT2G14610) secretion |
is compromised in |
(PARP1, AT2G31320) (APP, PARP2, PP, AT4G02390) mutants |
Arabidopsis thaliana |
| Bph14 |
encodes |
coiled-coil, nucleotide-binding site, leucine-rich repeat (CC-NB-LRR) protein |
Oryza sativa |
| mutations in NOX2 or its regulatory proteins |
cause |
chronic granulomatous disease |
|
| Pep3 expression |
is increased by |
PAMP (pathogen-associated molecular pattern) exposure |
Arabidopsis thaliana |
| reactive oxygen species (ROS) |
possess |
antimicrobial activities |
|
| AVRPM1A.2_3 |
did not trigger |
Pm1a-dependent HR |
Nicotiana benthamiana |
| TLP6-DN OE lines |
did not display reduced immunity against |
bacterial virulent pathogen Psm ES4326 |
Arabidopsis thaliana |
| (ATTLP1, TLP1, AT4G24180) ,2,5,6,10 mutant, TLP6-DN OE lines, and PI4Kβ2 OE lines |
did not show increased susceptibility to |
root pathogen Pseudomonas spp. N2C3 |
Arabidopsis thaliana |
| agroinfiltration |
causes increase in |
immune responses |
Nicotiana benthamiana |
| membrane receptor kinases (RKs) |
control |
plant immunity |
|
| flg22 immune response activation |
induces interaction between |
(UBC13A, UBC35, AT1G78870) and E3 ligase (AtPUB22, PUB22, AT3G52450) |
Arabidopsis thaliana |
| (IAN11, AT4G09930) |
is highly induced by |
nematode infection |
Arabidopsis thaliana |
| resistance against blast fungus |
is governed mainly by |
effector-triggered immunity (ETI) immune responses |
Oryza sativa |
| Pigm |
confers without |
yield penalty |
Oryza sativa |
| oxidized oligosaccharides |
were unable to induce |
(CYP81F2, AT5G57220) expression |
Arabidopsis thaliana |
| (AtNIK1, NIK1, AT5G16000) phosphorylation |
potentiates |
antiviral immunity |
|
| functional Rpa1 |
compared with |
non-functional Rpa1 K206A |
Nicotiana tabacum |
| p38 interfered with N but not with Rx1 function |
suggests that |
Rx1 mounts translational arrest of CP transcript using pathway distinct from N-mediated translational arrest |
Nicotiana benthamiana |
| phosphorylation status of (AtRIN4, RIN4, AT3G25070) |
leads to |
activation of resistance gene (RPM1, RPS3, AT3G07040) |
|
| ROS generated at the first phase of immune response |
are mostly |
apoplastic |
|
| PM3A-δ4 |
showed HR when combined with |
AVRPM3 A2/F2 -L116Y |
Nicotiana benthamiana |
| these compounds |
are known to enhance |
body's immune system to recognize and ravage cancer cells |
|
| (EVR, SOBIR1, AT2G31880) |
does not play a role in activating |
immune responses in KD-GmBIR1 roots |
Glycine max |
| BOTRYTIS-INDUCED KINASE1 (BIK1, AT2G39660) |
serves as signaling hub linking |
Pattern Recognition Receptors complex and downstream effectors |
Arabidopsis thaliana |
| chronic granulomatous disease patients |
suffer from |
chronic or recurrent bacterial and fungal infections |
|
| anther at 3 dpi |
does not switch on |
host defenses to combat infection |
Zea mays; Ustilago maydis |
| immune response activation |
relies on |
recognition of danger signals |
|
| vesicular bodies |
accumulate to form clusters at |
plasma membrane (PM) |
Arabidopsis thaliana |
| actin dynamics |
can be stimulated by |
MAMP application |
Arabidopsis thaliana |
| plants without functional HSP90s |
show lower accumulation of |
immune receptors including MLA1 and MLA6 |
|