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circadian clock regulation

12150 relationships annotated with this phrase. Showing first 500 of 12150.
Source entity Relationship Target entity Species
SbGhd7 has circadian clock-regulated expression pattern Sorghum bicolor
oscillating histone acetylation marks at volatile organic compound genes could be controlled by circadian clock proteins, either directly or indirectly
reversible and dynamic histone modifications oscillate at circadian clock gene loci
histone methylation marks such as H3K4me3 oscillate at circadian clock genes
ODO1 is itself regulated by plant circadian clock
chromatin modifications have been increasingly identified as regulatory layer in modulating circadian clock
reversible and dynamic histone modifications play essential role in maintaining precise phase of circadian clock in plants and mammals plants; mammals
ir-ztl plants have broadened peak transcript abundance of evening clock genes in LD Nicotiana attenuata
(ADO1, FKL2, LKP1, ZTL, AT5G57360) silencing strongly influences circadian clock in roots Nicotiana attenuata
(ADO1, FKL2, LKP1, ZTL, AT5G57360) knockout lengthens clock period by 4 h Arabidopsis thaliana
misexpression of (LUX, PCL1, AT3G46640) in N. attenuata could illuminate relative importance of direct and indirect functions of (ADO1, FKL2, LKP1, ZTL, AT5G57360) Nicotiana attenuata
LATE ELONGATED HYPOCOTYL (LHY, LHY1, AT1G01060) exhibit further enhanced expression in YHB–D seedlings
(AtCCA1, CCA1, AT2G46830) (CIRCADIAN CLOCK ASSOCIATED 1) and (LHY, LHY1, AT1G01060) (LATE ELONGATED HYPOCOTYL) dimers repress expression of evening-phased genes including GI and evening complex members
circadian clock regulates physiological processes and developmental transitions
activation of EARLY FLOWERING 4 (ELF4, AT2G40080) transcription mediated by FAR-RED IMPAIRED RESPONSE 1 (FAR1), FAR-RED ELONGATED HYPOCOTYL 3 (CPD45, FHY3, AT3G22170) and ELONGATED HYPOCOTYL 5 (HY5, TED 5, AT5G11260) contributes to circadian profile of expression of EARLY FLOWERING 4 (ELF4, AT2G40080)
SPINDLY (SPY) is necessary to maintain plant circadian clock pacing
YHB-dependent transcriptomes are enriched in up-regulated morning-phased genes
Rc suppresses YHB-regulated genes
(A-PUT2, bHLHb1, PIF5, PIL6, AT3G59060) overexpression line exhibits short circadian period in white light Arabidopsis thaliana
PIFs are involved in setting the pace of the clock
glycosylation of circadian clock proteins may be important in plants
protein glycosylation of circadian clock transcription factors results in opposite effects on protein stability in plants and animals
GmPRR3b H6 displays rhythmic and photoperiod-dependent expression rhythmic and photoperiod-dependent expression Glycine max
GmCCA1a-YFP overexpression callus confirmed that GmCCA1a could upregulate transcription of J/GmELF3a and other evening complex genes Glycine max
LOV/F-box/Kelch repeat family members contain unique arrangement of protein interaction domains that allow them to communicate light signals to factors controlling circadian clock and seasonal flowering time
unbiased target identification method identified multiple potential novel targets and regulatory partners of ZEITLUPE (ADO1, FKL2, LKP1, ZTL, AT5G57360) including TCP family transcription factor (AtCCA1, CCA1, AT2G46830) HIKING EXPEDITION (AtTCP21, CHE, TCP21, AT5G08330) Arabidopsis thaliana
(ADO1, FKL2, LKP1, ZTL, AT5G57360) misexpression dramatically affects circadian clock in leaves and flowers Nicotiana attenuata
(ADO1, FKL2, LKP1, ZTL, AT5G57360) (ADO3, FKF1, AT1G68050) (ADO2, LKP2, AT2G18915) triple mutant shows reduced amplitude compared with (ADO1, FKL2, LKP1, ZTL, AT5G57360) (ADO3, FKF1, AT1G68050) double mutant Arabidopsis thaliana
TIC transcripts in ir-ztl plants do not differ from TIC transcripts in EV plants Nicotiana attenuata
TPR domain is essential for SPINDLY (SPY) function Arabidopsis thaliana
PSEUDO-RESPONSE REGULATOR 5 (APRR5, PRR5, AT5G24470) is genetic downstream target of SPINDLY (SPY) Arabidopsis thaliana
phyABCDE mutant exhibits short circadian period in red light (low fluence) and white light Arabidopsis thaliana
(PIF1, PIL5, AT2G20180) (PAP3, PIF3, POC1, AT1G09530) (AtPIF4, PIF4, SRL2, AT2G43010) triple mutant exhibits long circadian period in white light (with 2% sucrose) Arabidopsis thaliana
(CPD45, FHY3, AT3G22170) mutant exhibits short period or arrhythmic circadian phenotype in white light Arabidopsis thaliana
addition of exogenous sugar can restore amplitude of (ATCRR2, CCR2, AT2G39180) and (AtCCA1, CCA1, AT2G46830) oscillations Arabidopsis thaliana
modulating GIGANTEA (GI) abundance will affect biological oscillator
ZEITLUPE (ADO1, FKL2, LKP1, ZTL, AT5G57360) interacts directly with (AtCCA1, CCA1, AT2G46830) HIKING EXPEDITION (AtTCP21, CHE, TCP21, AT5G08330) Arabidopsis thaliana
clock factors TIMING OF (AB165, CAB2, LHCB1.1, AT1G29920) EXPRESSION1 ( (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) sometimes called ) and PSEUDO-RESPONSE REGULATOR5 (APRR5, PRR5, AT5G24470) interact with all three family members
(ADO1, FKL2, LKP1, ZTL, AT5G57360) affects transcript abundance of circadian clock components Nicotiana attenuata
amplitude of mRNA rhythms of many genes, including core-clock genes are significantly dampened under constant darkness Arabidopsis thaliana
PIF-overexpressing lines show distinct clock behavior
casein kinase directly phosphorylates core circadian clock transcription factors
circadian clocks of plants and animals recruit similar cellular systems to regulate PTMs of circadian clock proteins
ZEITLUPE (ADO1, FKL2, LKP1, ZTL, AT5G57360) decoys interact with clock proteins Arabidopsis thaliana
expressing LOV KELCH PROTEIN2 (ADO2, LKP2, AT2G18915) decoy has intermediate effect on circadian clock Arabidopsis thaliana
ir-ztl plants have longer period in free-running conditions Nicotiana attenuata
high (ADO1, FKL2, LKP1, ZTL, AT5G57360) protein levels enhances degradation of targets in the dark Nicotiana attenuata
SPINDLY (SPY) fine-tunes circadian speed in nucleus by physically interacting with and affecting protein stability of PSEUDO-RESPONSE REGULATOR 5 (APRR5, PRR5, AT5G24470) Arabidopsis thaliana
(ATAN11, LWD1, AT1G12910) (LIGHT-REGULATED WD 1) (LWD2, AT3G26640) promote expression of (APRR5, PRR5, AT5G24470) (PSEUDO-RESPONSE REGULATOR 5)
(COR27, AT5G42900) mutant exhibits long circadian period in white light Arabidopsis thaliana
COLD-REGULATED GENE 28 (COR28, HUP41, AT4G33980) is transcriptionally regulated by circadian clock Arabidopsis thaliana
GmCCA1a might positively regulate transcription of J/GmELF3a Glycine max
GI (GIGANTEA) expression is negatively regulated by (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) (TIMING OF CAB EXPRESSION 1)
(HY3, OOP1, PHYB, AT2G18790) overexpression line exhibits short circadian period in dark, white light, and red light Arabidopsis thaliana
etiolated, temperature-entrained seedlings controls smaller set of genes than in light-entrained plants Arabidopsis thaliana
(HY5, TED 5, AT5G11260) binding to PRR9 promoter (APRR9, PRR9, TL1, AT2G46790) promoter Arabidopsis thaliana
ELONGATED HYPOCOTYL 5 (HY5, TED 5, AT5G11260) binding to core-clock gene promoters correlates with induction of ELONGATED HYPOCOTYL 5 (HY5, TED 5, AT5G11260)
sucrose-dependent circadian clock regulation is dependent on GI
rhythmic recruitment of chromatin-related factors to clock loci is enabled by circadian regulation of expression of chromatin-related factors and direct interaction of oscillator components with chromatin-related factors
O-glycosylation plays essential roles in modulating eukaryotic circadian clock systems
GI (GIGANTEA) helps sustain and modulate (ADO1, FKL2, LKP1, ZTL, AT5G57360) (ZEITLUPE) rhythmic accumulation
GI (GIGANTEA) expression is negatively regulated by evening complex (EC)
(AT-PHH1, ATCRY2, CRY2, FHA, PHH1, AT1G04400) mutant exhibits long circadian period in blue light (high fluence rate) Arabidopsis thaliana
(AtPIF4, PIF4, SRL2, AT2G43010) (A-PUT2, bHLHb1, PIF5, PIL6, AT3G59060) double mutant exhibits long circadian period in white light Arabidopsis thaliana
ELONGATED HYPOCOTYL 5 (HY5, TED 5, AT5G11260) and HOMOLOG (HYH, AT3G17609) only modulate amplitude of EARLY FLOWERING 4 (ELF4, AT2G40080) expression
circadian profile of expression of EARLY FLOWERING 4 (ELF4, AT2G40080) represents key component of the evening complex
(APRR7, PRR7, AT5G02810) co-binds with PIFs to many dawn-phased genes
(ATCOP1, COP1, DET340, EMB168, FUS1, AT2G32950) SUPPRESSOR 4 (CSU4, AT5G63440) represses transcriptional repression activity of CIRCADIAN CLOCK ASSOCIATED 1 (AtCCA1, CCA1, AT2G46830)
ZEITLUPE (ADO1, FKL2, LKP1, ZTL, AT5G57360) interacts with LOV KELCH PROTEIN 2 (ADO2, LKP2, AT2G18915)
(HY5, TED 5, AT5G11260) mutant plants exhibit a short period length under continuous light of different wavelengths
PHOTOREGULATORY PROTEIN KINASES (PPKs) integration and transduction of multiple light wavelengths ultimately affects circadian-clock rhythmicity
GmPRR3b H6 may act as general transcriptional repressor in central circadian oscillator machine Glycine max
GIGANTEA (GI) physically interacts with EARLY FLOWERING 4 (ELF4, AT2G40080) Arabidopsis thaliana
PRR (PSEUDO-RESPONSE REGULATOR) family is expressed sequentially as (APRR9, PRR9, TL1, AT2G46790) (APRR7, PRR7, AT5G02810) (APRR5, PRR5, AT5G24470) (APRR3, PRR3, AT5G60100) and (APRR1, AtTOC1, PRR1, TOC1, AT5G61380)
(ATCRY1, BLU1, CRY1, HY4, OOP2, AT4G08920) mutant free-running period difference is fluence rate dependent fluence rate of blue light Arabidopsis thaliana
SPINDLY (SPY) interacts with GIGANTEA (GI) Arabidopsis thaliana
PERIOD2 (PER2) functions at core of animal circadian clocks
CASEIN KINASE 1 LIKE family of proteins phosphorylates TIMING OF CAB EXPRESSION 1 (APRR1, AtTOC1, PRR1, TOC1, AT5G61380)
circadian clocks of plants and animals recruit similar cellular systems to regulate post-translational modifications (PTMs) of circadian clock proteins
metabolic status in (ATPPR5, EMB2453, PPR5, AT4G39620) O-fucosylation would be interesting to determine role in plant circadian clock regulation
GmCCA1a directly upregulates J/GmELF3a Glycine max
overexpression of YFP-H6 dramatically dampened amplitude of rhythmically expressed GmCAB1 Glycine max
COLD-REGULATED GENE 27 (COR27, AT5G42900) is transcriptionally regulated by circadian clock Arabidopsis thaliana
(APRR1, AtTOC1, PRR1, TOC1, AT5G61380) directly interacts with PIFs
PIFs are able to repress (AtCCA1, CCA1, AT2G46830) expression
(AT-PHH1, ATCRY2, CRY2, FHA, PHH1, AT1G04400) mutant phenotype shows slightly different results depending on experimental setup Arabidopsis thaliana
light-quality-dependent composition of (HY5, TED 5, AT5G11260) and transcription factor complexes could modulate the functioning of the circadian clock as a response to wavelength composition of white light
evening complex (EC) consists of (ELF3, PYK20, AT2G25930) (ELF4, AT2G40080) and (LUX, PCL1, AT3G46640) ARRYTHMO
this study demonstrates (ELF3, PYK20, AT2G25930) and GIGANTEA (GI) are essential clock time keepers Arabidopsis thaliana
(COR27, AT5G42900) and (COR28, HUP41, AT4G33980) repress expression of (APRR5, PRR5, AT5G24470)
(UCH3, AT4G17510) acts redundantly with (UCH1, AT5G16310) and (UCH2, AT1G65650) Arabidopsis thaliana
(APRR9, PRR9, TL1, AT2G46790) transcript peaks after (AtCCA1, CCA1, AT2G46830) (LHY, LHY1, AT1G01060)
(ATAN11, LWD1, AT1G12910) (LIGHT-REGULATED WD 1) and (LWD2, AT3G26640) is positive arm of the clock
phytochrome B (HY3, OOP1, PHYB, AT2G18790) regulates phase of core-clock genes
(APRR7, PRR7, AT5G02810) and PIFs are able to modulate expression of two pivotal core-clock genes
(HY5, TED 5, AT5G11260) binding to CCA1 promoter (AtCCA1, CCA1, AT2G46830) promoter Arabidopsis thaliana
(HY5, TED 5, AT5G11260) (HYH, AT3G17609) double mutant period phenotype occurs in darkness or white, blue, or red light Arabidopsis thaliana
protein glycosylation is important for circadian clock function in animal systems
metabolic status communication to circadian clock is mediated through (APRR7, PRR7, AT5G02810) homolog of (APRR5, PRR5, AT5G24470)
O-fucosylation might play evolutionarily conserved role in modulating circadian clock system
(APRR3, PRR3, AT5G60100) transcript is expressed after (APRR5, PRR5, AT5G24470) transcript
(LNK1, AT5G64170) to (LNK4, AT5G06980) (NIGHT LIGHT-INDUCIBLE AND CLOCK-REGULATED 1), (LCL1, RVE4, AT5G02840) (REVEILLE 4), (RVE6, AT5G52660) and (LCL5, RVE8, AT3G09600) is positive arm of the clock
(ADO1, FKL2, LKP1, ZTL, AT5G57360) (ZEITLUPE) promotes proteasomal degradation of (APRR5, PRR5, AT5G24470) (PSEUDO-RESPONSE REGULATOR 5)
(AT-PHH1, ATCRY2, CRY2, FHA, PHH1, AT1G04400) chromatin association could be modulated by PIF transcription factors Arabidopsis thaliana
O-fucosylation of (APRR5, PRR5, AT5G24470) may link metabolic status to plant circadian clock
GIGANTEA (GI) and EARLY FLOWERING 4 (ELF4, AT2G40080) work additively or synergistically in control of the circadian clock Arabidopsis thaliana
this study provides genetic support for the biochemical evidence of an EC-independent function of (ELF3, PYK20, AT2G25930) Arabidopsis thaliana
PSEUDO-RESPONSE REGULATOR 5 (APRR5, PRR5, AT5G24470) is SPY-interacting protein Arabidopsis thaliana
O-GlcNAcylation modulates circadian clock system in mammals
expression of a constitutively active form of phytochrome B (HY3, OOP1, PHYB, AT2G18790) can restore amplitude of (ATCRR2, CCR2, AT2G39180) and (AtCCA1, CCA1, AT2G46830) oscillations Arabidopsis thaliana
(AtPIF4, PIF4, SRL2, AT2G43010) overexpression can destabilize (ELF3, PYK20, AT2G25930)
(HY5, TED 5, AT5G11260) binding to LUX promoter (LUX, PCL1, AT3G46640) promoter Arabidopsis thaliana
mRNA levels of GmCCA1s, GmPRR3a, GmPRR5a, GmELF3s, GmELF4a, GmLUX1, and GmLUX2 decreased to varying degrees in YFP-H6 line Glycine max
35S:PRR5-GFP transgenic line shows no additive or synergistic effect with spy-3 mutant Arabidopsis thaliana
(LUX, PCL1, AT3G46640) ( ARRHYTHMO) binds LNK (NIGHT LIGHT-INDUCIBLE AND CLOCK-REGULATED) gene promoters
phytochrome B (HY3, OOP1, PHYB, AT2G18790) regulates transcriptional activity of core-clock genes
(ATCRY1, BLU1, CRY1, HY4, OOP2, AT4G08920) (CRYPTOCHROME 1) and (AT-PHH1, ATCRY2, CRY2, FHA, PHH1, AT1G04400) contribute to determining features of the endogenous oscillator Arabidopsis thaliana
(AtCCA1, CCA1, AT2G46830) (CIRCADIAN CLOCK ASSOCIATED 1) and (LHY, LHY1, AT1G01060) (LATE ELONGATED HYPOCOTYL) form homo- and heterodimers that bind evening element promoter motif
double (ATCRY1, BLU1, CRY1, HY4, OOP2, AT4G08920) (AT-PHH1, ATCRY2, CRY2, FHA, PHH1, AT1G04400) mutant exhibits longer period compared with wild-type or single-mutant plants Arabidopsis thaliana
(HY5, TED 5, AT5G11260) binding to BOA (BROTHER OF (LUX, PCL1, AT3G46640) ARRHYTHMO) promoter correlated with changes in BOA expression level Arabidopsis thaliana
(ELF4, AT2G40080) is evening/night player of the clock
dark causes dissociation of (ADO1, FKL2, LKP1, ZTL, AT5G57360) (ZEITLUPE) and GI (GIGANTEA)
photoreceptor families (except phototropins) contribute to setting circadian clock pace Arabidopsis thaliana
GmPRR3b and GmCCA1a genes displayed comparable rhythmic expression patterns in callus and trifoliate leaves Glycine max
EARLY FLOWERING 3 (ELF3, PYK20, AT2G25930) function is not solely dependent on evening complex (EC) Arabidopsis thaliana
(AtCCA1, CCA1, AT2G46830) (CIRCADIAN CLOCK ASSOCIATED 1) encodes MYB-like transcription factor
(AT-TCP20, ATTCP20, PCF1, TCP20, AT3G27010) (TEOSINTE BRANCHED1-CYCLOIDEA-PCF 20) and (AtTCP22, TCP22, AT1G72010) recruit (ATAN11, LWD1, AT1G12910) (LIGHT-REGULATED WD 1)
(CPD45, FHY3, AT3G22170) mutant exhibits long period or arrhythmic circadian phenotype in red light Arabidopsis thaliana
(ATCRY1, BLU1, CRY1, HY4, OOP2, AT4G08920) mutants and double (AT-PHH1, ATCRY2, CRY2, FHA, PHH1, AT1G04400) mutants present differences on period length under red light Arabidopsis thaliana
UV-B light pulses induce transcription of several core-clock genes Arabidopsis thaliana
DE-ETIOLATED 1 (ATDET1, DET1, FUS2, AT4G10180) interacts with LONG HYPOCOTYL YELLOW (LHY, LHY1, AT1G01060)
(LCL5, RVE8, AT3G09600) (REVEILLE 8) is MYB-like transcription factor
PIFs (phytochrome-interacting factors) repress expression of (AtCCA1, CCA1, AT2G46830) (CIRCADIAN CLOCK ASSOCIATED 1)
circadian clock is proposed to work as integrator of endogenous and external signals
(HY5, TED 5, AT5G11260) mutant exhibits short circadian period in dark, blue, red, and white light Arabidopsis thaliana
PIF transcriptional activity affects expression pattern of core-clock genes
DE-ETIOLATED 1 (ATDET1, DET1, FUS2, AT4G10180) is essential for determining pace of the oscillator
casein kinase functions in regulation of circadian period
expression of ZmBiP2 undergoes diurnal oscillations Zea mays
overlap of diurnal expression patterns of ZmCCA1b and ZmBiP2 indicates that ZmCCA1b may be positive regulator of ZmBiP2 in circadian clock manner Zea mays
HISTONE DEACETYLASE-6 (ATHDA6, AXE1, HDA6, HDAC6, RPD3B, RTS1, SIL1, AT5G63110) regulates expression of morning- and evening-expressed clock genes
TIME OF CAB EXPRESSION 1 (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) interacts with ZEITLUPE (ADO1, FKL2, LKP1, ZTL, AT5G57360)
(HY5, TED 5, AT5G11260) (ELONGATED HYPOCOTYL 5) was found to associate with many core-clock genes Arabidopsis thaliana
(HY5, TED 5, AT5G11260) binding to (LUX, PCL1, AT3G46640) promoter correlated with changes in (LUX, PCL1, AT3G46640) expression level Arabidopsis thaliana
DE-ETIOLATED 1 (ATDET1, DET1, FUS2, AT4G10180) interaction with CIRCADIAN CLOCK ASSOCIATED 1 (AtCCA1, CCA1, AT2G46830) and LATE ELONGATED HYPOCOTYL (LHY, LHY1, AT1G01060) is believed to allow its recruitment to the promoter of TIMING OF CAB EXPRESSION 1 (APRR1, AtTOC1, PRR1, TOC1, AT5G61380)
glycosylation of circadian clock proteins may be important in plants
EARLY FLOWERING 3 (ELF3, PYK20, AT2G25930) assembles into evening complex (EC) Arabidopsis thaliana
TCP family transcription factor (AtCCA1, CCA1, AT2G46830) HIKING EXPEDITION (AtTCP21, CHE, TCP21, AT5G08330) is critical clock regulator Arabidopsis thaliana
phytochrome photoactivation transcriptionally induces CIRCADIAN CLOCK ASSOCIATED 1 (AtCCA1, CCA1, AT2G46830)
HDA6-LDL1/2 complex interacts with (AtCCA1, CCA1, AT2G46830) and (LHY, LHY1, AT1G01060)
(COR27, AT5G42900) (COLD REGULATED GENE 27) and (COR28, HUP41, AT4G33980) proteins bind to promoters of (APRR5, PRR5, AT5G24470) and (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) Arabidopsis thaliana
mammalian cryptochromes are not able to directly interact with human (ATCOP1, COP1, DET340, EMB168, FUS1, AT2G32950) ortholog Homo sapiens
internal-external signalling synchronization is vital for clock-controlled pathways such as flowering time and hypocotyl elongation Arabidopsis thaliana
rhythmic cellular programs is controlled by environmental cues and endogenous circadian clocks
(ELF4, AT2G40080) assembles into evening complex (EC) Arabidopsis thaliana
CIRCADIAN CLOCK ASSOCIATED 1 (AtCCA1, CCA1, AT2G46830) favors histone deacetylation
POFUT activity of SPINDLY (SPY) is critical for SPY effect on circadian period Arabidopsis thaliana
EC binds to and regulates (AtPIF4, PIF4, SRL2, AT2G43010) and (A-PUT2, bHLHb1, PIF5, PIL6, AT3G59060) expression
repression of (APRR7, PRR7, AT5G02810) imply higher expression of (AtCCA1, CCA1, AT2G46830) (LHY, LHY1, AT1G01060)
(ADO1, FKL2, LKP1, ZTL, AT5G57360) abundance peak at the end of the day could contribute to physiological role of (ADO1, FKL2, LKP1, ZTL, AT5G57360) associated with regulation of (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) and (APRR5, PRR5, AT5G24470) and (AtTCP21, CHE, TCP21, AT5G08330) stability
exogenous sucrose application shortens circadian clock period in constant light
circadian clock regulates gene expression and ensures precise synchronization with external environment Arabidopsis thaliana
Histone 3 (H3) acetylation correlates with transcriptional rhythms of clock gene expression
cis-regulatory elements function in circadian clock
transcriptionally permissive chromatin conformations correlates with rhythmic recruitment of transcriptional machinery
DE-ETIOLATED 1 (ATDET1, DET1, FUS2, AT4G10180) interacts with CIRCADIAN CLOCK ASSOCIATED 1 (AtCCA1, CCA1, AT2G46830)
GmPRR3b H6 is key component of circadian oscillator Glycine max
HISTONE DEACETYLASE-6 (ATHDA6, AXE1, HDA6, HDAC6, RPD3B, RTS1, SIL1, AT5G63110) interacts with LYSINE-SPECIFIC DEMETHYLASE 1 (ATLSD1, ATSWP1, KDM1C, LDL1, LSD1, SWP1, AT1G62830) -LIKE 1/2 ( /2)
plant circadian clock regulates expression of at least one-third of all genes Arabidopsis thaliana
circadian condition (constant light) following entrainment in diurnal conditions (long-day) resulted in ZmBiP2 expression increased from zeitgeber time 0 (ZT0 = dawn), peaked at ZT4, and decreased at dusk Zea mays
HISTONE ACETYLTRANSFERASE OF THE TAFII250 FAMILY 2 (HAF2, TAF1, TAF1B, AT3G19040) activates clock genes expressed close to dusk or during the night
HISTONE DEACETYLASE-6 (ATHDA6, AXE1, HDA6, HDAC6, RPD3B, RTS1, SIL1, AT5G63110) forms a protein complex with Groucho/Tup1 protein family, topless/topless-related ( (TPL, WSIP1, AT1G15750) /TPR), and (APRR9, PRR9, TL1, AT2G46790)
HISTONE DEACETYLASE-6 (ATHDA6, AXE1, HDA6, HDAC6, RPD3B, RTS1, SIL1, AT5G63110) interacts with (APRR9, PRR9, TL1, AT2G46790) (AtCCA1, CCA1, AT2G46830) (LHY, LHY1, AT1G01060) and (APRR1, AtTOC1, PRR1, TOC1, AT5G61380)
HISTONE DEACETYLASE 9 (AtHDA9, AtHDAC9, HDA09, HDA9, HDAC9, AT3G44680) interacts with EARLY FLOWERING 3 (ELF3, PYK20, AT2G25930)
PSEUDO-RESPONSE REGULATOR 5 (APRR5, PRR5, AT5G24470) is major downstream target of SPINDLY (SPY) Arabidopsis thaliana
(LCL5, RVE8, AT3G09600) (REVEILLE 8) and (LNK1, AT5G64170) and (LNK2, AT3G54500) complex bind (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) (TIMING OF CAB EXPRESSION 1) promoter
TIME OF CAB EXPRESSION 1 (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) interacts with FLAVIN-BINDING KELCH REPEAT F-BOX 1 (ADO3, FKF1, AT1G68050)
higher levels of PIFs induce shortening of free-running period
pifq mutants exhibit delayed occurrence of peak of expression of (AtCCA1, CCA1, AT2G46830) and (LHY, LHY1, AT1G01060)
PSEUDO-RESPONSE REGULATOR 5 (APRR5, PRR5, AT5G24470) is critical for circadian clock function
high glucose increases PER2 O-GlcNAcylation
evening complex (EC) binds to promoters of genes involved in circadian clock
EARLY FLOWERING 3 (ELF3, PYK20, AT2G25930) can function independently of evening complex (EC) Arabidopsis thaliana
oscillator genes are rhythmically decorated with different chromatin marks
Arabidopsis cryptochromes mediate light regulation of the circadian clock Arabidopsis thaliana
plant (ATINO80, INO80, AT3G57300) complex may contribute to circadian clock gene expression in plants
high expression of (APRR7, PRR7, AT5G02810) would translate to strong repression of (AtCCA1, CCA1, AT2G46830) (LHY, LHY1, AT1G01060)
DE-ETIOLATED 1 (ATDET1, DET1, FUS2, AT4G10180) directly interacts with CIRCADIAN CLOCK ASSOCIATED 1 (AtCCA1, CCA1, AT2G46830)
phosphorylation is post-translational modification important in eukaryotic circadian clocks
exogenous sucrose application helps sustain oscillations in constant dark
cor27-2 cor28-2 mutant TOC1 and PRR5 expression would be increased in (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) and (APRR5, PRR5, AT5G24470)
CIRCADIAN CLOCK ASSOCIATED 1 (AtCCA1, CCA1, AT2G46830) controls expression of HISTONE ACETYLTRANSFERASE OF THE TAFII250 FAMILY 2 (HAF2, TAF1, TAF1B, AT3G19040)
PSEUDORESPONSE REGULATOR 9 (APRR9, PRR9, TL1, AT2G46790) is direct target of PSEUDORESPONSE REGULATOR 7 (APRR7, PRR7, AT5G02810) Arabidopsis thaliana
Cuscuta australis convergently lost genes involved in circadian clock Cuscuta australis
REVEILLE 8 (LCL5, RVE8, AT3G09600) activates (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) expression
potential regulators of circadian function have major effects on circadian function Arabidopsis thaliana
TIMING OF CHLOROPHYLL A/B BINDING PROTEIN ( (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) ) inhibits transcription of LATE ELONGATED HYPOCOTYL (LHY, LHY1, AT1G01060) Arabidopsis thaliana
SA effects on the clock are fully mimicked by H2O2 treatment Arabidopsis thaliana
Arabidopsis clock is composed of interlocking negative feedback loops Arabidopsis thaliana
GENERAL CONTROL NONDEREPRESSIBLE 5 (BGT, GCN5, HAC3, HAG01, HAG1, HAT1, AT3G54610) may be involved in transcriptional regulation of clock genes
SAP30 FUNCTION-RELATED 1 (AFR1, AT1G75060) and (AFR2, AT1G19330) favor histone deacetylation at (AtCCA1, CCA1, AT2G46830) and (APRR9, PRR9, TL1, AT2G46790) promoters
Gastrodia elata convergently lost genes involved in circadian clock Gastrodia elata
SAP30 FUNCTION-RELATED 1 (AFR1, AT1G75060) and (AFR2, AT1G19330) repress expression of (AtCCA1, CCA1, AT2G46830) and (APRR9, PRR9, TL1, AT2G46790)
post-translational control particularly involves regulated proteolysis Arabidopsis thaliana
GENERAL CONTROL NONDEREPRESSIBLE 5 (BGT, GCN5, HAC3, HAG01, HAG1, HAT1, AT3G54610) may directly interact with clock proteins
(AtTCP21, CHE, TCP21, AT5G08330) and TIMING OF CAB EXPRESSION1 (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) regulates expression of CIRCADIAN CLOCK ASSOCIATED1 (AtCCA1, CCA1, AT2G46830) Arabidopsis thaliana
prr579 triple mutant has constitutively high CIRCADIAN CLOCK-ASSOCIATED 1 (AtCCA1, CCA1, AT2G46830) RNA levels Arabidopsis thaliana
(AtCCA1, CCA1, AT2G46830) and (LHY, LHY1, AT1G01060) might form part of additional regulatory feedback loop Arabidopsis thaliana
transcriptional/translational negative-feedback loops generate ∼24 hr oscillation
altered regulation of BvFT1 / BvFT2 is effected downstream of circadian clock Beta vulgaris
PHYTOCHROME-INTERACTING FACTORS (PIFs) activity is gated to dawn Arabidopsis thaliana
(AtCCA1, CCA1, AT2G46830) (CIRCADIAN CLOCK ASSOCIATED 1) binds CCA1-binding site (CBS; AAAAAATCT) Arabidopsis thaliana
pseudogenes/transposons are severely underrepresented among circadian regulated transcripts Arabidopsis thaliana
specific flanking sequences might modify phase conferred by a CCRE Arabidopsis thaliana
PSEUDO RESPONSE REGULATOR 5 (APRR5, PRR5, AT5G24470) inhibits transcription of LATE ELONGATED HYPOCOTYL (LHY, LHY1, AT1G01060) Arabidopsis thaliana
TIC functions in regulation of circadian clock
cryptochromes are involved in blue-light-independent regulation of the circadian clock Arabidopsis thaliana
(LIP1, AT5G64813) could be involved in the regulation of abundance or nucleo-cytoplasmic distribution of its yet unknown target
transient SA treatment in NPR1-OX plants does not reduce clock amplitude Arabidopsis thaliana
EARLY FLOWERING 3 (ELF3, PYK20, AT2G25930) protein level may not be important for correct clock function Arabidopsis thaliana
TIMING OF CAB EXPRESSION 1 ( (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) ) is target of PRR-PIF interplay Arabidopsis thaliana
(AtCCA1, CCA1, AT2G46830) (CIRCADIAN CLOCK ASSOCIATED 1) directly binds circadian clock regulatory element (CCRE) in (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) promoter Arabidopsis thaliana
(AtCCA1, CCA1, AT2G46830) (CIRCADIAN CLOCK ASSOCIATED 1) binds directly to (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) (TIMING OF CAB EXPRESSION 1) promoter Arabidopsis thaliana
different combinations of four known CCREs will next be critical to determine whether are sufficient to confer every phase of circadian transcript accumulation Arabidopsis thaliana
transient SA treatment causes significant amplitude reduction in wild-type plants Arabidopsis thaliana
elf3-4 mutants show high levels of (APRR9, PRR9, TL1, AT2G46790) expression Arabidopsis thaliana
EEs (evening elements) are under-represented in promoters of genes with transcripts accumulating at other times Arabidopsis thaliana
constitutive reduction in TIMING OF CAB EXPRESSION 1 (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) expression raises levels of LONG HYPOCOTYL 5 (LHY) expression Arabidopsis thaliana
genes that encode casein kinase I (CKI) have a pivotal function in mammalian circadian clock
circadian clock in roots differs markedly from circadian clock in shoots Arabidopsis thaliana
SlCDF1 and SlCDF3 expression levels followed similar pattern consisting of upregulated levels during the second half of the night and the first part of the day Solanum lycopersicum
CIRCADIAN CLOCK ASSOCIATED (AtCCA1, CCA1, AT2G46830) represses expression of (LUX, PCL1, AT3G46640) ARRYTHMO Arabidopsis thaliana
Evening Complex ( (ELF3, PYK20, AT2G25930) (ELF4, AT2G40080) (LUX, PCL1, AT3G46640) ) regulates expression of (APRR9, PRR9, TL1, AT2G46790) directly Arabidopsis thaliana
LATE ELONGATED HYPOCOTYL (LHY, LHY1, AT1G01060) activates transcription of PSEUDO RESPONSE REGULATOR 7 (APRR7, PRR7, AT5G02810) Arabidopsis thaliana
light and temperature regulate plant clock function Arabidopsis
single-leaf Pst DC3000 infection in (ATRBOHD, DELT1, RBOHD, AT5G47910) mutant plants causes similar amplitude and robustness reduction as in wild-type plants Arabidopsis thaliana
EARLY FLOWERING 3 (ELF3, PYK20, AT2G25930) interacts with CIRCADIAN CLOCK ASSOCIATED 1 (AtCCA1, CCA1, AT2G46830) Arabidopsis thaliana
multipronged promoter motif discovery and validation approach developed to identify motifs important for time-of-day-specific circadian expression Arabidopsis thaliana
EARLY FLOWERING 4 (ELF4, AT2G40080) is direct target of CIRCADIAN CLOCK-ASSOCIATED 1 (AtCCA1, CCA1, AT2G46830) Arabidopsis thaliana
Pst DC3000 infection slightly advances phase of (AtCCA1, CCA1, AT2G46830) LUC+ rhythms Arabidopsis thaliana
RBOHD-dependent ROS triggers systemic clock period and phase phenotypes observed after localized Pst DC3000 infection Arabidopsis thaliana
(ATCBF1, CBF1, DREB1B, AT4G25490) overexpression alters other clock gene transcripts Arabidopsis thaliana
different analytical strategies and gene lists despite using many of the same motifs show phase-specific enrichment Arabidopsis thaliana
AtNFXL-2 mutant provides link between clock and biotic and abiotic stress responses Arabidopsis thaliana
(LIP1, AT5G64813) plays a negative role in controlling circadian period
SA treatment in npr1-1 plants causes greater phase delay Arabidopsis thaliana
tubby-like protein (TLP) transcription factor family does not have previously described links to circadian clock Arabidopsis thaliana
circadian system can confer competitive advantage Arabidopsis thaliana
(AtTCP21, CHE, TCP21, AT5G08330) interacts with TIMING OF CAB EXPRESSION1 (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) Arabidopsis thaliana
circadian clock components are largely conserved between monocots and dicots
(ELF3, PYK20, AT2G25930) probably affects the clock via the transcription of (AtCCA1, CCA1, AT2G46830) (LHY, LHY1, AT1G01060)
rhythmic cycling of the mRNA dampened in 35S::SlCDF3 transgenic plants Arabidopsis thaliana
PSEUDO RESPONSE REGULATOR 9 (APRR9, PRR9, TL1, AT2G46790) inhibits transcription of LATE ELONGATED HYPOCOTYL (LHY, LHY1, AT1G01060) Arabidopsis thaliana
circadian clock constitutes complex regulatory network formed by multiple interlocked transcriptional and translational feedback loops Arabidopsis thaliana
(AtTEM1, EDF1, TEM1, AT1G25560) and (AtRAV2, EDF2, RAP2.8, RAV2, TEM2, AT1G68840) diurnal expression profiles show lower peak of expression in the dark phase in short days (SDs) Arabidopsis thaliana
Arabidopsis circadian oscillator is composed of several interlocking positive and negative feedback loops Arabidopsis thaliana
(ADO3, FKF1, AT1G68050) promotes degradation of PSEUDO-RESPONSE REGULATOR 5 (APRR5, PRR5, AT5G24470) Arabidopsis thaliana
LOV domains of ZEITLUPE (ADO1, FKL2, LKP1, ZTL, AT5G57360) LOV KELCH PROTEIN2 (ADO2, LKP2, AT2G18915) and FLAVIN-BINDING, KELCH REPEAT, F-BOX1 (ADO3, FKF1, AT1G68050) are predicted to interact with TIMING OF (AB165, CAB2, LHCB1.1, AT1G29920) EXPRESSION1 ( (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) sometimes called ) and PSEUDO-RESPONSE REGULATOR5 (APRR5, PRR5, AT5G24470)
YHB alters clock output
eukaryotic circadian clocks employ SCF-type E3 ligases to mediate ubiquitylation of clock factors
expressing ZEITLUPE (ADO1, FKL2, LKP1, ZTL, AT5G57360) decoy has greatest effect on circadian clock Arabidopsis thaliana
pseudo-response regulator (PRR) protein has homology to circadian clock-associated genes Arabidopsis thaliana; Beta vulgaris
nuclear pore complex (NPC) specifically modulates clock function Arabidopsis thaliana
teosinte branched1/cycloidia/PCF (TCP) transcription factor family does not have previously described links to circadian clock Arabidopsis thaliana
LATE ELONGATED HYPOCOTYL (LHY, LHY1, AT1G01060) represses expression of (LUX, PCL1, AT3G46640) ARRYTHMO Arabidopsis thaliana
(LIP1, AT5G64813) contributes to robustness and accuracy of the plant circadian clockwork
LATE ELONGATED HYPOCOTYL (LHY, LHY1, AT1G01060) overall expression was reduced in roots compared with shoots
perturbation of expression of clock-regulated TCP genes causes phenotypes often found in clock mutants Arabidopsis thaliana
GIGANTEA (GI) is known oscillator component Arabidopsis thaliana
GI is implicated in response of the circadian clock to sucrose Arabidopsis thaliana
(LHY, LHY1, AT1G01060) transcripts oscillate in EV plants under both LD and LL conditions Nicotiana attenuata
LOV KELCH PROTEIN2 (ADO2, LKP2, AT2G18915) decoys interact with clock proteins Arabidopsis thaliana
PSEUDORESPONSE REGULATOR 9 (APRR9, PRR9, TL1, AT2G46790) represses CIRCADIAN CLOCK ASSOCIATED 1 (AtCCA1, CCA1, AT2G46830) Arabidopsis thaliana
PSEUDO-RESPONSE REGULATORS (APRR9, PRR9, TL1, AT2G46790) /7/5 are negative regulators of hypocotyl elongation Arabidopsis thaliana
SNP in AtNFXL-2 is the likely cause of early bird (ebi-1) phenotype Arabidopsis thaliana
oscillations in (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) chromatin occupancy coincide with evening peak of TIMING OF CAB EXPRESSION 1 (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) protein rhythms Arabidopsis thaliana
toc1-2 mutant raises levels of PSEUDO-RESPONSE REGULATOR 7 (APRR7, PRR7, AT5G02810) expression Arabidopsis thaliana
differentially expressed genes are enriched for dawn and dusk phases of light transition Arabidopsis thaliana
(SRR1, AT5G59560) has a function in setting the period of the circadian clock Arabidopsis thaliana
Pseudomonas syringae pv. tomato DC3000 (Pst DC3000) infection results in low amplitude and long period clock rhythms Arabidopsis thaliana
evening loop involves at least TIME OF CAB EXPRESSION 1 (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) and GIGANTEA (GI) Arabidopsis thaliana
PSEUDO-RESPONSE REGULATOR 9 (APRR9, PRR9, TL1, AT2G46790) is a known repressor of CIRCADIAN CLOCK ASSOCIATED 1 (AtCCA1, CCA1, AT2G46830) and LATE ELONGATED HYPOCOTYL (LHY, LHY1, AT1G01060) Arabidopsis thaliana
CBS (CCA1-binding site) is not over-represented in any phase groups Arabidopsis thaliana
morning element (ME; AACCACGAAAAT) when multimerized confers dawn-phased expression on luciferase reporter gene Arabidopsis thaliana
LONG HYPOCOTYL 5 (LHY) is known oscillator component Arabidopsis thaliana
light dramatically shortens periods in (ADO1, FKL2, LKP1, ZTL, AT5G57360) mutants
strong loss-of-function (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) mutants have even shorter periods than (LIP1, AT5G64813) mutant
systemic signal triggered by localized Pst DC3000 infection reduces amplitude of clock rhythms in untreated tissues Arabidopsis thaliana
CCACA motif is almost identical to ME (morning element) computationally defined by Michael and coworkers Arabidopsis thaliana
(LIP1, AT5G64813) function is fully suppressed at those fluence rates where lip1-1 plants display WT periods
EARLY FLOWERING 3 (ELF3, PYK20, AT2G25930) association with (APRR9, PRR9, TL1, AT2G46790) promoter provides mechanism for EARLY FLOWERING 3 (ELF3, PYK20, AT2G25930) direct and indirect effects on clock network Arabidopsis thaliana
late day-phased motif contains GATA core element Arabidopsis thaliana
Michael and coworkers found PBX (protein box element) motif Arabidopsis thaliana
MYB-related transcription factor family has previously described links to circadian clock Arabidopsis thaliana
CIRCADIAN CLOCK ASSOCIATED 1 (AtCCA1, CCA1, AT2G46830) is known oscillator component Arabidopsis thaliana
toc1-2 mutant raises levels of PSEUDO-RESPONSE REGULATOR 9 (APRR9, PRR9, TL1, AT2G46790) expression Arabidopsis thaliana
systemic signal triggered by localized Pst DC3000 infection lengthens period of clock rhythms in untreated tissues Arabidopsis thaliana
EARLY FLOWERING 3 (ELF3, PYK20, AT2G25930) affects evening loop Arabidopsis thaliana
CYCLING DOF FACTOR 5 (CDF5, AT1G69570) accumulates specifically at dawn Arabidopsis thaliana
GATA core element is found within longer EE (evening element) motif Arabidopsis thaliana
LATE ELONGATED HYPOCOTYL (LHY, LHY1, AT1G01060) is able to inhibit gene expression in shoots Arabidopsis thaliana
transient SA treatment in npr1-1 plants causes significantly greater amplitude reduction Arabidopsis thaliana
phytochrome-interacting factors (PIFs) accumulate progressively during night Arabidopsis thaliana
CBS (CCA1-binding site) is only under-represented in one phase group Arabidopsis thaliana
SA treatment at different times of day reduces amplitude to similar extent Arabidopsis thaliana
EARLY FLOWERING 3 (ELF3, PYK20, AT2G25930) has binding partners including GIGANTEA (GI) Arabidopsis thaliana
circadian morning-to-midnight waves of PSEUDO-RESPONSE REGULATORS ( (APRR9, PRR9, TL1, AT2G46790) (APRR7, PRR7, AT5G02810) (APRR5, PRR5, AT5G24470) and (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) ) jointly gate PHYTOCHROME-INTERACTING FACTORS (PIFs) activity Arabidopsis thaliana
CBS (CCA1-binding site) has been suggested to be phase-specific CCRE present in promoters of dawn-phased genes Arabidopsis thaliana
PSEUDO-RESPONSE REGULATOR 7 (APRR7, PRR7, AT5G02810) is known oscillator component Arabidopsis thaliana
DMG LOC106312920 is annotated as two-component response regulator-like (APRR1, AtTOC1, PRR1, TOC1, AT5G61380)
transient H2O2 treatment does not affect robustness and period of circadian rhythms Arabidopsis thaliana
TIMING OF CAB EXPRESSION 1 (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) represses PSEUDORESPONSE REGULATOR 9 (APRR9, PRR9, TL1, AT2G46790) Arabidopsis thaliana
rhythmic expression behavior is likely controlled by Arabidopsis circadian clock Arabidopsis thaliana
CIRCADIAN CLOCK ASSOCIATED (AtCCA1, CCA1, AT2G46830) represses expression of EARLY FLOWERING 3 (ELF3, PYK20, AT2G25930) Arabidopsis thaliana
evening complex ( (ELF3, PYK20, AT2G25930) (ELF4, AT2G40080) and (LUX, PCL1, AT3G46640) ) regulates expression of PSEUDO RESPONSE REGULATOR 9 (APRR9, PRR9, TL1, AT2G46790) Arabidopsis thaliana
EARLY FLOWERING 3 (ELF3, PYK20, AT2G25930) allows rhythmicity in cca1-11 lhy-21 double mutant Arabidopsis thaliana
ELF4-ELF3-LUX complex mediates nighttime repression of PSEUDO-RESPONSE REGULATOR 9 (APRR9, PRR9, TL1, AT2G46790) PSEUDO-RESPONSE REGULATOR 7 (APRR7, PRR7, AT5G02810) GIGANTEA (GI), and LUXARRHYTHMO (LUX, PCL1, AT3G46640) genes
(APRR1, AtTOC1, PRR1, TOC1, AT5G61380) target genes display early morning phase Arabidopsis thaliana
dusk-phased genes are potentially indirectly regulated by TIMING OF CAB EXPRESSION 1 (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) Arabidopsis thaliana
SECRET AGENT (SEC) does not modulate pace of the Arabidopsis circadian clock Arabidopsis thaliana
core-clock components and PIFs convergence of regulation of clock outputs
(ATCRY1, BLU1, CRY1, HY4, OOP2, AT4G08920) (CRYPTOCHROME 1) and (AT-PHH1, ATCRY2, CRY2, FHA, PHH1, AT1G04400) play important roles in proper functioning of the endogenous oscillator Arabidopsis thaliana
light-quality-dependent composition of (HY5, TED 5, AT5G11260) and transcription factor complexes could modulate functioning of the circadian clock
casein kinase functions in regulation of the circadian period
similar defects in EC component mutants suggests conserved genetic relationship between GIGANTEA (GI) and other evening complex (EC) components Arabidopsis thaliana
(LHY, LHY1, AT1G01060) (LATE ELONGATED HYPOCOTYL) encodes MYB-like transcription factor
(ELF3, PYK20, AT2G25930) (EARLY FLOWERING 3), (ELF4, AT2G40080) and (LUX, PCL1, AT3G46640) ( ARRHYTHMO) interact to form evening complex (EC)
(LCL1, RVE4, AT5G02840) (REVEILLE 4), (RVE6, AT5G52660) and (LCL5, RVE8, AT3G09600) induce expression of PRR (PSEUDO-RESPONSE REGULATOR) family
results from resetting ability studies suggest that (ATCRY1, BLU1, CRY1, HY4, OOP2, AT4G08920) and (AT-PHH1, ATCRY2, CRY2, FHA, PHH1, AT1G04400) are partially functionally redundant Arabidopsis thaliana
(ATCOP1, COP1, DET340, EMB168, FUS1, AT2G32950) mutants exhibit circadian phenotypes
EARLY FLOWERING 3 (ELF3, PYK20, AT2G25930) interacts with LATE ELONGATED HYPOCOTYL (LHY, LHY1, AT1G01060) Arabidopsis thaliana
circadian control of EARLY FLOWERING 3 (ELF3, PYK20, AT2G25930) expression requires morning loop components CIRCADIAN CLOCK ASSOCIATED 1 (AtCCA1, CCA1, AT2G46830) and LATE ELONGATED HYPOCOTYL (LHY, LHY1, AT1G01060) Arabidopsis thaliana
CIRCADIAN CLOCK ASSOCIATED 1 (AtCCA1, CCA1, AT2G46830) and LATE ELONGATED HYPOCOTYL (LHY, LHY1, AT1G01060) act to repress evening gene expression in early morning Arabidopsis thaliana
light enhances clock amplitude
(AtCCA1, CCA1, AT2G46830) (CIRCADIAN CLOCK ASSOCIATED 1) and (LHY, LHY1, AT1G01060) (LATE ELONGATED HYPOCOTYL) negatively regulate expression of PRR (PSEUDO-RESPONSE REGULATOR) family members
GI (GIGANTEA) interacts with in a blue-light-enhanced manner (ADO1, FKL2, LKP1, ZTL, AT5G57360) (ZEITLUPE)
(COR28, HUP41, AT4G33980) mutant exhibits long circadian period in white light Arabidopsis thaliana
PIFs functioning as calibration system modulates pace of the oscillator
(AEL4, MLK1, PPK2, AT5G18190) (AEL3, MLK2, PPK3, AT3G03940) and (AEL1, MLK3, PPK4, AT2G25760) single mutants exhibit long period phenotype
plants have recruited O-fucosylation to control circadian clock function
O-GlcNAcylation allows for metabolic entrainment of the circadian clock
same PTMs can have different functional outcomes
(COR27, AT5G42900) and (COR28, HUP41, AT4G33980) bind to chromatin of circadian clock-related genes Arabidopsis thaliana
(LUX, PCL1, AT3G46640) ARRHYTHMO was similarly expressed in shoots and roots
EARLY FLOWERING 3 (ELF3, PYK20, AT2G25930) mutant shows same trends as phyABCDE in controlling nighttime gene expression nighttime gene expression Arabidopsis thaliana
plant clock is organ-specific but not organ-autonomous Arabidopsis thaliana
metabolic pathways controlled by circadian clock likely employ different mechanisms from circadian clock genes
EARLY FLOWERING 3 (ELF3, PYK20, AT2G25930) overexpressor has mild phenotypic effect on clock network Arabidopsis thaliana
bacterial infection alters core clock gene expression Arabidopsis thaliana
PSEUDO-RESPONSE REGULATOR 3 (APRR3, PRR3, AT5G60100) are significantly repressed only in YHB–D seedlings
EARLY FLOWERING 4 (ELF4, AT2G40080) is another clock gene
REVEILLE 1 (RVE1, AT5G17300) and CYCLING DOF FACTOR 5 (CDF5, AT1G69570) expression is under strong circadian control and peaks at dawn circadian clock Arabidopsis thaliana
GI protein indirectly modulates clock outputs Arabidopsis thaliana
(AtCCA1, CCA1, AT2G46830) (LHY, LHY1, AT1G01060) and (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) are involved in temperature compensation Arabidopsis thaliana
modulation of PIF activity by GIGANTEA (GI) is required for adequate phasing of output rhythms such as growth Arabidopsis thaliana
(HY5, TED 5, AT5G11260) (HYH, AT3G17609) and BBX genes (BBX set A) expression still peaked at dawn in prr5 prr7 prr9 but generally higher and persisted longer (APRR5, PRR5, AT5G24470) (APRR7, PRR7, AT5G02810) (APRR9, PRR9, TL1, AT2G46790) mutant Arabidopsis thaliana
GI (GIGANTEA) induces transcription of (AtCCA1, CCA1, AT2G46830) (CIRCADIAN CLOCK ASSOCIATED 1)
(PIF1, PIL5, AT2G20180) (AtPIF4, PIF4, SRL2, AT2G43010) (A-PUT2, bHLHb1, PIF5, PIL6, AT3G59060) triple mutant exhibits long circadian period in white light (with 2% sucrose) Arabidopsis thaliana
(HYH, AT3G17609) mutant exhibits short circadian period in blue light Arabidopsis thaliana
DE-ETIOLATED 1 (ATDET1, DET1, FUS2, AT4G10180) represses transcription of TIMING OF CAB EXPRESSION 1 (APRR1, AtTOC1, PRR1, TOC1, AT5G61380)
(COR27, AT5G42900) and (COR28, HUP41, AT4G33980) bind to chromatin of TIMING OF CAB EXPRESSION 1 (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) /PSEUDO-RESPONSE REGULATOR 1
(APRR1, AtTOC1, PRR1, TOC1, AT5G61380) ( [TIMING OF CAB EXPRESSION 1]) is expressed after (APRR3, PRR3, AT5G60100) transcript
PIF transcription factors were already implicated on fine-tuning of the oscillator Arabidopsis thaliana
(LUX, PCL1, AT3G46640) gene affects circadian clock Arabidopsis thaliana
(ELF3, PYK20, AT2G25930) negatively regulates period length
Pst DC3000 infection results in approximately 0.5 hr longer period of clock rhythms Arabidopsis thaliana
NONEXPRESSER OF PR GENES 1 (ATNPR1, NIM1, NPR1, SAI1, AT1G64280) antagonizes systemic amplitude reduction of clock rhythms observed after single-leaf Pst DC3000 infection Arabidopsis thaliana
EARLY FLOWERING 3 (ELF3, PYK20, AT2G25930) regulates clock genes Arabidopsis thaliana
phase distributions of circadian-regulated genes containing CBS examined to evaluate biological relevance of CBS Arabidopsis thaliana
TIMING OF CAB EXPRESSION 1 (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) acts as repressor Arabidopsis thaliana
SA pulse phenocopies amplitude reduction observed after localized Pst DC3000 inoculation Arabidopsis thaliana
EARLY FLOWERING 3 (ELF3, PYK20, AT2G25930) affects morning loop Arabidopsis thaliana
clades of related motifs identified by clustering based on sequence similarity Arabidopsis thaliana
Arabidopsis circadian clock is made up of small number of genes Arabidopsis thaliana
toc1-2 mutant raises levels of GIGANTEA (GI) expression Arabidopsis thaliana
(APRR1, AtTOC1, PRR1, TOC1, AT5G61380) repression occurs through (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) rhythmic association to the promoters of the oscillator genes Arabidopsis
CIRCADIAN CLOCK ASSOCIATED 1 (AtCCA1, CCA1, AT2G46830) is able to inhibit gene expression in shoots Arabidopsis thaliana
ELONGATED HYPOCOTYL 5 (HY5, TED 5, AT5G11260) has predicted targets including TIMING OF CAB EXPRESSION 1 (TOC1) TIMING OF CAB EXPRESSION 1 (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) Arabidopsis thaliana
LATE ELONGATED HYPOCOTYL (LHY, LHY1, AT1G01060) represses expression of TIMING OF CHLOROPHYLL A/B BINDING PROTEIN (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) Arabidopsis thaliana
excessive PIF activity in gi-2 may be responsible for low amplitude of CIRCADIAN CLOCK ASSOCIATED 1 (AtCCA1, CCA1, AT2G46830) Arabidopsis thaliana
morning and evening oscillator loops are connected through the repressing activity of TIMING OF CAB EXPRESSION 1 (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) Arabidopsis
CIRCADIAN CLOCK ASSOCIATED 1 (AtCCA1, CCA1, AT2G46830) is not able to inhibit gene expression in roots Arabidopsis thaliana
dual effects of gi mutations on photoperiodic flowering and clock-regulated gene expression are separated by some mutant alleles Arabidopsis thaliana
dual effects of gi mutations on photoperiodic flowering and clock-regulated gene expression are separated in plants overexpressing GI Arabidopsis thaliana
(APRR7, PRR7, AT5G02810) and (APRR9, PRR9, TL1, AT2G46790) are involved in regulation of central oscillator Arabidopsis thaliana
(ADO1, FKL2, LKP1, ZTL, AT5G57360) affects the clock at posttranscriptional level
Pst DC3000 infection does not cause phase advance in (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) promoter-driven oscillations Arabidopsis thaliana
EARLY FLOWERING 3 (ELF3, PYK20, AT2G25930) represses many genes at night (Zeitgeber time 12–20) Arabidopsis thaliana
CONSTITUTIVE PHOTOMORPHOGENESIS 1 (ATCOP1, COP1, DET340, EMB168, FUS1, AT2G32950) and DE-ETIOLATED 1 (ATDET1, DET1, FUS2, AT4G10180) interaction with clock components is important for regulation of clock gene expression
PSEUDO-RESPONSE REGULATOR 7 (APRR7, PRR7, AT5G02810) is important for cyclic gene expression Arabidopsis thaliana
HISTONE DEACETYLASE-6 (ATHDA6, AXE1, HDA6, HDAC6, RPD3B, RTS1, SIL1, AT5G63110) complex modulates pattern of H3 deacetylation
periods of Cab1R:LUC expression rhythms were very similar between Nipponbare and N-NIL(Hd16) under DL, LL and DD conditions Oryza sativa
LATE ELONGATED HYPOCOTYL (LHY, LHY1, AT1G01060) is not able to inhibit gene expression in roots Arabidopsis thaliana
(ATCOP1, COP1, DET340, EMB168, FUS1, AT2G32950) regulation of light input to circadian clock via modulation of circadian rhythms and flowering Arabidopsis thaliana
TIC transcripts in roots of N. attenuata do not oscillate circadian rhythm Nicotiana attenuata
catalytic domain is essential for SPINDLY (SPY) function Arabidopsis thaliana
rapid effect of light on abundance of key clockwork components could affect regulation of expression of downstream targets Arabidopsis thaliana
(APRR7, PRR7, AT5G02810) is core-clock component and (AtCCA1, CCA1, AT2G46830) (LHY, LHY1, AT1G01060) transcriptional repressor
daily alternation of light and darkness leads to evolution of rhythmic cellular programs
REVEILLE 8 (LCL5, RVE8, AT3G09600) enhances histone acetylation
PRR proteins consist of C-terminal (CCT, CRP, MED12, AT4G00450) [CONSTANS (CO), CO-like, TOC1] domain
light directs circadian rhythms
mechanism whereby YHB alters clock output is likely to be complex
LOV/F-box/Kelch repeat family of F-boxes has three members ZEITLUPE (ADO1, FKL2, LKP1, ZTL, AT5G57360) LOV KELCH PROTEIN2 (ADO2, LKP2, AT2G18915) and FLAVIN-BINDING, KELCH REPEAT, F-BOX1 (ADO3, FKF1, AT1G68050)
(APRR1, AtTOC1, PRR1, TOC1, AT5G61380) transcripts oscillate in EV plants under both LD and LL conditions Nicotiana attenuata
TIMING OF CAB EXPRESSION 1 (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) are significantly repressed only in YHB–D seedlings
several mutants and transgenics defective in circadian clock function have altered diel patterns of growth and of starch turnover Arabidopsis thaliana
(LUX, PCL1, AT3G46640) transcripts oscillate in EV plants under both LD and LL conditions Nicotiana attenuata
expression of (LUX, PCL1, AT3G46640) in ir-ztl lines is higher than expression of (LUX, PCL1, AT3G46640) in control plants at midday Nicotiana attenuata
phytochrome photoactivation transcriptionally induces LATE ELONGATED HYPOCOTYL (LHY, LHY1, AT1G01060)
Rc-dependent signaling pathways compensate for regulation of YHB-mediated gene expression
LOV KELCH PROTEIN2 (ADO2, LKP2, AT2G18915) regulates clock period Arabidopsis thaliana
(ELF4, AT2G40080) transcripts oscillate in EV plants under both LD and LL conditions Nicotiana attenuata
(ADO3, FKF1, AT1G68050) and ZEITLUPE (ADO1, FKL2, LKP1, ZTL, AT5G57360) complex controls expression of LATE ELONGATED HYPOCOTYL (LHY, LHY1, AT1G01060) Arabidopsis thaliana
ZEITLUPE (ADO1, FKL2, LKP1, ZTL, AT5G57360) regulates clock period Arabidopsis thaliana
altering clock protein degradation can change period length of the clock
ZEITLUPE (ADO1, FKL2, LKP1, ZTL, AT5G57360) is required for maintaining daily rhythms of (AtCCA1, CCA1, AT2G46830) HIKING EXPEDITION (AtTCP21, CHE, TCP21, AT5G08330) protein Arabidopsis thaliana
(ADO1, FKL2, LKP1, ZTL, AT5G57360) (ZEITLUPE) promotes proteasomal degradation of (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) (TIMING OF CAB EXPRESSION 1)
GIGANTEA (GI) interacts with LOV KELCH PROTEIN 2 (ADO2, LKP2, AT2G18915)
FAR-RED IMPAIRED RESPONSE 1 (FAR1, AT5G22500) and FAR-RED ELONGATED HYPOCOTYL 3 (CPD45, FHY3, AT3G22170) are essential for amplitude and rhythmic expression of EARLY FLOWERING 4 (ELF4, AT2G40080)
PHYTOCHROME INTERACTING FACTOR (PIF) proteins can repress CIRCADIAN CLOCK ASSOCIATED 1 (AtCCA1, CCA1, AT2G46830) expression Arabidopsis thaliana
all three LOV/F-box/Kelch repeat proteins are necessary for robust 24-h rhythmicity Arabidopsis thaliana
CIRCADIAN CLOCK ASSOCIATED 1 (AtCCA1, CCA1, AT2G46830) exhibit further enhanced expression in YHB–D seedlings
(ADO1, FKL2, LKP1, ZTL, AT5G57360) (ADO3, FKF1, AT1G68050) and (ADO2, LKP2, AT2G18915) decoys demonstrate effects on circadian clock Arabidopsis thaliana
ir-ztl plants significantly influences expression of circadian clock genes Nicotiana attenuata
YHB and Rc synergistically enhance EARLY FLOWERING 4 (ELF4, AT2G40080) expression
NaZTL interacts directly with NaTOC1 Nicotiana attenuata
Rc could be due to light-dependent alteration of the amplitude, phase, and/or period of clock signaling
(LHY, LHY1, AT1G01060) transcripts are significantly lower in ir-ztl versus EV plants under both conditions Nicotiana attenuata
expressing FLAVIN-BINDING, KELCH REPEAT, F-BOX1 (ADO3, FKF1, AT1G68050) decoy has least effect on circadian clock Arabidopsis thaliana
expression of (ELF4, AT2G40080) in ir-ztl lines is higher than expression of (ELF4, AT2G40080) in control plants at midday Nicotiana attenuata
TIMING OF (AB165, CAB2, LHCB1.1, AT1G29920) EXPRESSION1 ( (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) sometimes called ) and PSEUDO-RESPONSE REGULATOR5 (APRR5, PRR5, AT5G24470) are destabilized through interactions with LOV/F-box/Kelch repeat proteins
individual (ADO3, FKF1, AT1G68050) knockout has little or no effect on clock Arabidopsis thaliana
TIC in N. attenuata has different role compared with TIC in Arabidopsis Nicotiana attenuata; Arabidopsis thaliana
FLAVIN-BINDING, KELCH REPEAT, F-BOX1 (ADO3, FKF1, AT1G68050) regulates clock period Arabidopsis thaliana
GIGANTEA (GI) are significantly repressed only in YHB–D seedlings
(HY5, TED 5, AT5G11260) mutants display shorter period rhythms in blue light Arabidopsis thaliana
PSEUDO-RESPONSE REGULATOR 9 (APRR9, PRR9, TL1, AT2G46790) displays sequential peak of expression and activity during the day Arabidopsis thaliana
multiple regulatory mechanisms are responsible for regulation of rhythmic gene and protein expression and activity Arabidopsis thaliana
HISTONE DEACETYLASE 9 (AtHDA9, AtHDAC9, HDA09, HDA9, HDAC9, AT3G44680) favors histone deacetylation at (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) promoter
HISTONE DEACETYLASE 9 (AtHDA9, AtHDAC9, HDA09, HDA9, HDAC9, AT3G44680) and EARLY FLOWERING 3 (ELF3, PYK20, AT2G25930) repress expression of (APRR1, AtTOC1, PRR1, TOC1, AT5G61380)
CIRCADIAN CLOCK ASSOCIATED 1 (AtCCA1, CCA1, AT2G46830) represses (APRR1, AtTOC1, PRR1, TOC1, AT5G61380)
ZEITLUPE (ADO1, FKL2, LKP1, ZTL, AT5G57360) FLAVIN-BINDING, KELCH REPEAT, F-BOX1 (ADO3, FKF1, AT1G68050) and LOV KELCH PROTEIN2 (ADO2, LKP2, AT2G18915) play roles in circadian clock and regulation of seasonal flowering time
(ADO1, FKL2, LKP1, ZTL, AT5G57360) (ADO3, FKF1, AT1G68050) double mutant exhibits longer period than (ADO1, FKL2, LKP1, ZTL, AT5G57360) mutant alone Arabidopsis thaliana
CIRCADIAN CLOCK ASSOCIATED 1 (AtCCA1, CCA1, AT2G46830) and LATE ELONGATED HYPOCOTYL (LHY, LHY1, AT1G01060) inhibit expression of EARLY FLOWERING 3 (ELF3, PYK20, AT2G25930)
(ELF3, PYK20, AT2G25930) confers evening complex (EC) thermal responsiveness Arabidopsis thaliana
(ADO3, FKF1, AT1G68050) promotes degradation of TIMING OF CAB EXPRESSION 1 (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) Arabidopsis thaliana
CO is expressed at same phase as (APRR1, AtTOC1, PRR1, TOC1, AT5G61380)
TIMING OF CAB EXPRESSION 1 (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) is PSEUDO-RESPONSE REGULATOR 1 (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) Arabidopsis thaliana
interlocking, dual feed-back loop model of the clock was required to match phase delay of CO RNA accumulation
photoregulatory protein kinases (PPK1–4) are involved in phosphorylation of proteins involved in circadian clock
circadian clock does not tightly control dawn burst of BBX set A, HY5, and HYH dawn burst Arabidopsis thaliana
(LUX, PCL1, AT3G46640) occupancy of target loci is strongly reduced at warmer temperatures Arabidopsis thaliana
(APRR1, AtTOC1, PRR1, TOC1, AT5G61380) is required to maintain circadian period length at high temperature
evening element (EE) ([A]AAATATCT) motif is bound by LATE ELONGATED HYPOCOTYL (LHY, LHY1, AT1G01060)
ELONGATED HYPOCOTYL 5 (HY5, TED 5, AT5G11260) has been found to affect circadian clock circadian clock Arabidopsis thaliana
SA treatment in (ATRBOHD, DELT1, RBOHD, AT5G47910) mutant plants continues to cause amplitude reduction Arabidopsis thaliana
EARLY FLOWERING 3 (ELF3, PYK20, AT2G25930) has binding partners including CIRCADIAN CLOCK ASSOCIATED 1 (AtCCA1, CCA1, AT2G46830) Arabidopsis thaliana
EARLY FLOWERING 3 (ELF3, PYK20, AT2G25930) protein is required for correct clock function Arabidopsis thaliana
other important CCREs may be yet to be discovered Arabidopsis thaliana
early bird (ebi-1) mutant is circadian clock mutation Arabidopsis thaliana
toc1-2 mutant raises levels of LONG HYPOCOTYL 5 (LHY) expression Arabidopsis thaliana
PSEUDO-RESPONSE REGULATOR (PRR) 9, 7, 5 and (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) proteins repress CIRCADIAN CLOCK ASSOCIATED 1 (AtCCA1, CCA1, AT2G46830) and LATE ELONGATED HYPOCOTYL (LHY, LHY1, AT1G01060)
(HY5, TED 5, AT5G11260) (HYH, AT3G17609) mutant shows altered transcription of BOA
(HY5, TED 5, AT5G11260) mutants show short period rhythms
intracellular or subcellular oscillations of Mg2+ indirectly modulate transcription-translation feedback loop (TTFL) oscillator Arabidopsis thaliana; Homo sapiens
(APRR2, PRR2, AT4G18020) is directly bound by (GF14 CHI, GRF1, AT4G09000) or (GRF3, RCI1, AT5G38480)
LUXARRHYTHMO (LUX, PCL1, AT3G46640) are significantly repressed only in YHB–D seedlings
direct effect of ELONGATED HYPOCOTYL 5 (HY5, TED 5, AT5G11260) on apparently non-responsive clock genes could be masked by feedback from the clock gene network Arabidopsis thaliana
absence of ELONGATED HYPOCOTYL 5 (HY5, TED 5, AT5G11260) and -HOMOLOG (HYH, AT3G17609) severely attenuates transcription rate of EARLY FLOWERING 4 (ELF4, AT2G40080) :LUC
Model 2a comprises single transcriptional feedback loop
biological clock is composed of transcriptional-translational feedback loops (TTFL)
core-clock components are repressed by each of these molecules ( (ELF3, PYK20, AT2G25930) (ELF4, AT2G40080) (LUX, PCL1, AT3G46640) GI, PRR, (APRR1, AtTOC1, PRR1, TOC1, AT5G61380) (AtCCA1, CCA1, AT2G46830) (LHY, LHY1, AT1G01060) )
(FHY2, FRE1, HY8, PHYA, AT1G09570) overexpression line exhibits short circadian period in red light and darkness Arabidopsis thaliana
(ATCRY1, BLU1, CRY1, HY4, OOP2, AT4G08920) overexpression line exhibits short circadian period in blue and white light Arabidopsis thaliana
(ATCRY1, BLU1, CRY1, HY4, OOP2, AT4G08920) (AT-PHH1, ATCRY2, CRY2, FHA, PHH1, AT1G04400) double mutant exhibits long circadian period in blue light and red light (low fluence rate) Arabidopsis thaliana
(ADO1, FKL2, LKP1, ZTL, AT5G57360) regulates circadian clock in roots Nicotiana attenuata
SPINDLY (SPY) specifically mediates modulation of circadian clock Arabidopsis thaliana
plants entrained with light/dark cycles and transferred to continuous light controls larger set of genes than in etiolated seedlings Arabidopsis thaliana
(AT-PHH1, ATCRY2, CRY2, FHA, PHH1, AT1G04400) binds several core-clock gene promoters Arabidopsis thaliana
SECRET AGENT (SEC) shows no role for plant circadian clock function
(CPD45, FHY3, AT3G22170) and (FAR1, AT5G22500) negatively regulate flowering time under both long-day and short-day conditions through transcriptional regulation of (ELF4, AT2G40080) Arabidopsis thaliana
DEGs in gi-2 overlap with DEGs in cca1-1;lhy-11 Arabidopsis thaliana
direct interaction of oscillator components with chromatin-related factors enables rhythmic changes in chromatin
(APRR1, AtTOC1, PRR1, TOC1, AT5G61380) assembles into a protein complex comprising NF-YB/C
SAP30 FUNCTION-RELATED 1 (AFR1, AT1G75060) and (AFR2, AT1G19330) bind to (AtCCA1, CCA1, AT2G46830) and (APRR9, PRR9, TL1, AT2G46790) gene promoters
(ADO1, FKL2, LKP1, ZTL, AT5G57360) protein levels accumulate at high levels during evening Nicotiana attenuata
spy-8 prr5-1 double mutant shows null mutation of PRR5 is partially epistatic to spy-8 mutant Arabidopsis thaliana
GI (GIGANTEA) expression is negatively regulated by (AtCCA1, CCA1, AT2G46830) (CIRCADIAN CLOCK ASSOCIATED 1) (LHY, LHY1, AT1G01060) (LATE ELONGATED HYPOCOTYL)
(ELF3, PYK20, AT2G25930) represses PIF4 protein activity upon association
GI can hinder binding of PIFs to chromatin
PIFs functioning as calibration system modulates amplitude of the oscillator
(AT-PHH1, ATCRY2, CRY2, FHA, PHH1, AT1G04400) mutants have more elusive phenotype Arabidopsis thaliana
(HY5, TED 5, AT5G11260) (HYH, AT3G17609) double mutant has shorter period than wild-type plants under free-running conditions Arabidopsis thaliana
PIF mutation alleviates low expression of CIRCADIAN CLOCK ASSOCIATED 1 (AtCCA1, CCA1, AT2G46830) Arabidopsis thaliana
pif4-101;pif5-1 double mutant displays lengthened period in pCCA1 promoter activity under free-running conditions Arabidopsis thaliana
(HY3, OOP1, PHYB, AT2G18790) mutant exhibits long circadian period in red light Arabidopsis thaliana
(AT-PHH1, ATCRY2, CRY2, FHA, PHH1, AT1G04400) mutant exhibits short circadian period in blue light (low fluence rate) Arabidopsis thaliana
EARLY FLOWERING 4 (ELF4, AT2G40080) interacts with EARLY FLOWERING 3 (ELF3, PYK20, AT2G25930)
(APRR9, PRR9, TL1, AT2G46790) (APRR7, PRR7, AT5G02810) and (APRR5, PRR5, AT5G24470) bind (PIF7, AT5G61270)