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autophagy

24744 relationships annotated with this phrase. Showing first 500 of 24744.
Source entity Relationship Target entity Species
GFP-MoAtg8 in P131 cultured in MM-N starvation condition for 2.5 h was delivered into vacuole as a symbol of autophagy events Magnaporthe oryzae
vacuolar delivery of autophagosomes results in breakdown of GFP-Atg8 into free GFP Magnaporthe oryzae
deubiquitination of autophagy-related protein Atg8 impacts autophagy process Fusarium graminearum
enhancing autophagy affected fungal development
small GTPase FgRab7 directly regulates (APG9, ATAPG9, ATG9, AT2G31260) trafficking Fusarium graminearum
GFP-MoAtg8 localization in cytoplasm in Δ Moemc5 and Δ Moemc2 suggests that autophagy did not occur in these two mutants Magnaporthe oryzae
transcriptional factor Gln3 regulates nonselective autophagy by targeting promoter region of (APG9, ATAPG9, ATG9, AT2G31260)
environmental stressors that restrict metabolic capacity (nutrient-starvation, low-light, and the high-temperature treatment which increased metabolic rate and resource demand) stimulate an up-regulation of genes and pathways associated with the breakdown of macromolecules (autophagy and the lysosome) Thalassiosira pseudonana
enhancing autophagy affected virulence
yeast proteins Sec12 and (ATVPS52, POK, TTD8, VPS52, AT1G71270) are essential for autophagosome formation via regulation of yeast (APG9, ATAPG9, ATG9, AT2G31260) trafficking Saccharomyces cerevisiae
yeast proteins Sec7 and Sec2 are essential for autophagosome formation via regulation of yeast (APG9, ATAPG9, ATG9, AT2G31260) trafficking Saccharomyces cerevisiae
impaired autophagy results in reduced appressorium pressure Magnaporthe oryzae
ubiquitin-specific protease 15 (UBP15, AT1G17110) has as substrate autophagy-related protein ATG8 Fusarium graminearum
conidium undergoes autophagy Magnaporthe oryzae
Δ Moemc5 mutant insensitivity to rapamycin suggests that contribution of Emc5 to autophagy is not related to (TOR, AT1G50030) signaling pathway Magnaporthe oryzae
(APG9, ATAPG9, ATG9, AT2G31260) is required for autophagy Magnaporthe oryzae
Δ Moemc5 and Δ Moemc2 strains strongly affects steady-state protein level of membrane protein Atg9-GFP Magnaporthe oryzae
transcriptional factor Gln3 regulates nonselective autophagy by targeting promoter region of ATG8
MpPUB9-Citrine and DsRed-AtATG8e were also colocalized autophagy-related structures Nicotiana benthamiana
MoEmc5 and MoEmc2 are important in autophagy during appressoria formation and in starvation conditions Magnaporthe oryzae
autophagy was delayed in PH-1::GFP-Atg8 K35R and PH-1::GFP-Atg8 K69R mutants Fusarium graminearum
p62 recruits ATG8
lateral root (LR) defect in ark2-1/pub9-1 double mutants could be result of defective autophagy process in this mutant Arabidopsis thaliana
autophagic machinery is needed for degradation of lipid droplets in vacuoles Chlamydomonas reinhardtii
cerulenin might be valuable tool with which to dissect retrograde signaling from the plastid to the nucleus and to identify selective substrates of autophagy in chloroplast-stressed cells Chlamydomonas
transcriptional factor (RPH1, AT2G48070) regulates nonselective autophagy by targeting promoter region of (APG7, ATAPG7, ATATG7, ATG7, PEUP4, AT5G45900)
EMC complex is a direct regulator of autophagy Magnaporthe oryzae
deletion of the histone acetyltransferase (BGT, GCN5, HAC3, HAG01, HAG1, HAT1, AT3G54610) caused reduced acetylation level of Atg8 Fusarium graminearum
MpEXO70.1 colocalizes with (ATATG8E, ATG8E, AT2G45170) Marchantia polymorpha; Arabidopsis thaliana
(UBP15, AT1G17110) negatively regulates autophagy in F. graminearum Fusarium graminearum
transcriptional factor Ume6 regulates nonselective autophagy by targeting promoter region of (APG9, ATAPG9, ATG9, AT2G31260)
Ubp15-mediated deubiquitination of Atg8 is required for the localization of Atg8 and the proper autophagy process in F. graminearum Fusarium graminearum
ATG8 played critical roles in controlling major steps of autophagy
MpPUB9 localization in autophagy-related structures possibly regulated by plant EXO70 paralogs Marchantia polymorpha
ATG8-interacting motif in EXO70 proteins supports idea that the functions of EXO70 paralogs may be connected to autophagy regulation Arabidopsis thaliana
PB1CP may utilize PAMP-inducible interaction with (ATRBOHD, DELT1, RBOHD, AT5G47910) through C-terminus
deubiquitination of Atg8 influences localization of Atg8 Fusarium graminearum
(ATPUB9, PUB9, AT3G07360) and (ARK2, AtARK2, RK2, AT1G65800) coexpressed with ATG8 complete colocalization of (ATPUB9, PUB9, AT3G07360) and ATG8 on punctate subcellular compartments Nicotiana tabacum
(ATPUB9, PUB9, AT3G07360) localizes to autophagic bodies after phosphate starvation Arabidopsis thaliana
orthologs of yeast core ATGs are found in plant species
phosphatidylinositol 3-kinase (ATVPS34, PI3K, VPS34, AT1G60490) is known to play major role in autophagosome formation
autophagy is important for cell survival in extended darkness Arabidopsis thaliana
stress increases autophagic degradation activity
(ATATG3, ATG3, AT5G61500) (APG7, ATAPG7, ATATG7, ATG7, PEUP4, AT5G45900) and ATG8 proteins are involved in expansion and completion of autophagosome Chlamydomonas
autophagy-related protein5 (APG5, ATATG5, ATG5, AT5G17290) and (APG8A, ATG8A, AT4G21980) are essential for N and carbon remobilization Arabidopsis thaliana
autophagosomes in protoplasts are observed during autophagy in dark-induced leaf senescence Hordeum vulgare
vacuolar-processing enzyme 2c (VPE2c) is less upregulated with level increasing 1.2-fold on day 3, 1.75-fold on day 7 and 1.15-fold on day 10 of dark-induced leaf senescence Hordeum vulgare
autophagy level could be quantitatively measured by comparing free GFP with the total of free GFP and GFP-Atg8 in immunoblots Magnaporthe oryzae
EMC is direct modulator in autophagosome formation
recombinant rACBP3 plays crucial roles in PE-related autophagy Arabidopsis thaliana
human EMC6 directly interacts with (ATRAB-F2A, ATRAB5A, ATRABF2A, RAB-F2A, RAB5A, RABF2A, RHA1, AT5G45130) Homo sapiens
autophagosome-vacuole pathway is transport pathway in the endomembrane system
autophagy maintains cellular homeostasis
ubiquitin-specific protease 15 (UBP15, AT1G17110) is involved in the deubiquitination of ATG8 Fusarium graminearum
EXO70.2 subgroup has roles in autophagy
transcriptional factor Gln3 regulates nonselective autophagy by targeting promoter region of (APG7, ATAPG7, ATATG7, ATG7, PEUP4, AT5G45900)
fungal autophagy modulates host plasma membrane dynamics at the BIC Magnaporthe oryzae; Oryza sativa
autophagosomes were not detected in starved mycelium vacuoles of Δ Moemc5 and Δ Moemc2 Magnaporthe oryzae
Atg9-containing compartments are source of membranes for formation and/or expansion of autophagosomes
Arabidopsis exocyst subunit (ATEXO70B2, EXO70B2, AT1G07000) was transported to vacuole Arabidopsis thaliana
PB1CP might function as autophagy cargo receptor for (ATRBOHD, DELT1, RBOHD, AT5G47910)
PB1CP-mediated relocalization of (ATRBOHD, DELT1, RBOHD, AT5G47910) may also involve autophagy
genes adjacent to active LTR-REs are enriched in pathways of autophagy Phyllostachys edulis
MpPUB9-mediated turnover of MpEXO70.1 modulates under high-salt conditions Marchantia polymorpha
Several genes involved in the autophagy process were down-regulated T411 line Chlamydomonas reinhardtii
chloroplast integrity is linked to autophagy Chlamydomonas reinhardtii
monodansylcadaverine is used to stain autophagosomes
GFP-Atg8 labeled autophagosomes in conidia and appressoria of WT P131 contain much more than autophagosomes in Δ Moemc5 and Δ Moemc2 Magnaporthe oryzae
Arabidopsis exocyst subunit (ATEXO70B2, EXO70B2, AT1G07000) interacted with AtATG8 Arabidopsis thaliana
number of punctate structures after ConcA treatment and Pi/Suc starvation dramatically increased in ConcA-treated and Pi/Suc-starved root cells Arabidopsis thaliana
Magnaporthe oryzae endoplasmic reticulum membrane complex (EMC) regulates biogenesis of membrane proteins for autophagy Magnaporthe oryzae
autophagy might be impaired in Δ Moemc5 and Δ Moemc2 Magnaporthe oryzae
overexpression of PB1CP may enhance endocytosis and degradation of (ATRBOHD, DELT1, RBOHD, AT5G47910)
PrxQA localization pattern in stromules suggests transport of damaged PrxQA through stromules to autophagic vesicles Physcomitrella patens
photodamaged chloroplasts are subjected to chlorophagy Arabidopsis thaliana
autophagy can acquire degradation substrates either selectively or randomly
(ATG13B, AT3G18770) is induced in Haberlea rhodopensis during darkness Haberlea rhodopensis
autophagy is evolutionarily conserved major pathway
autophagy can be highly selective autophagy
ATG genes from the core autophagy machinery is up-regulated when Chlamydomonas cells are exposed to different stress conditions Chlamydomonas
vacuolar-processing enzyme alpha (αVPE) is more highly upregulated from 1.8-fold on day 3 to 3.1-fold on day 10 of dark-induced leaf senescence Hordeum vulgare
turnover of macromolecules via selective autophagy may contribute to nutrient recycling Hordeum vulgare
coexpression analysis using ATTED-II microarray data suggested that coexpression network is related to autophagy, para-aminobenzoic acid metabolic process, and nuclear mRNA splicing via spliceosome Arabidopsis thaliana
autophagy importance in nutrient recycling has been demonstrated in Arabidopsis, maize, and rice Arabidopsis thaliana; Zea mays; Oryza sativa
autophagy is important aspect of class III (ATVPS34, PI3K, VPS34, AT1G60490) signaling
(TOR, AT1G50030) and autophagy and protein degradation connection is being gathered for in plants
core ATGs are required for formation of autophagosomal membranes
Phosphatidylinositol 3-kinase (ATVPS34, PI3K, VPS34, AT1G60490) signaling is connected to starvation-induced autophagy
proteaphagy is one of selective autophagy
autophagic degradation eliminates toxic components
ATG8 binding to phosphatidylethanolamine is key step in autophagosome formation
ATG8 protein is strongly up-regulated following FAS inhibition Chlamydomonas
recycled cell contents provide amino acids
cerulenin-treated cells show increased mRNA levels of ATG12 gene Chlamydomonas
cerulenin blocks activation of autophagy by nitrogen starvation yeast
cerulenin-treated cells and ClpP-depleted cells both activate chloroplast stress response and autophagy Chlamydomonas
core ATGs (ATG1–ATG10, ATG12–ATG14, (atg16, AT5G50230) and ATG18) are essential for all types of autophagy
double membrane structure forms autophagosome
plastid lipid bodies are engulfed by autophagosome-like structures Micrasterias denticulata
interaction between Arabidopsis Receptor Kinase2 (ARK2, AtARK2, RK2, AT1G65800) and Arabidopsis U box/armadillo repeat-containing E3 ubiquitin ligase9 (ATPUB9, PUB9, AT3G07360) results in accumulation of Arabidopsis U box/armadillo repeat-containing E3 ubiquitin ligase9 (ATPUB9, PUB9, AT3G07360) in autophagosomes Nicotiana tabacum
punctate structures are identified as autophagic bodies Arabidopsis thaliana
autophagic protein degradation genes was mid-reverse down-regulated rather than early-reverse Chlamydomonas reinhardtii
cerulenin-treated cells showed induction of autophagy pathway Chlamydomonas reinhardtii
autophagy is also activated in C. reinhardtii under stress conditions and in the presence of ROS Chlamydomonas reinhardtii
(ATATG18D, ATG18D, AT3G56440) is induced in Haberlea rhodopensis during darkness Haberlea rhodopensis
autophagic degradation recycles cell contents
(AtDPE1, DPE1, AT5G64860) (MEX1, RCP1, AT5G17520) double mutant exhibits autophagy-like chloroplast degradation Arabidopsis thaliana
measured increase in F0 could be consequence of autophagic process
punctate structures are lytic compartments or autophagosomes
construct expressing GFP-ATG8 fusion protein allows visualization of ATG8-labeled autophagosomal structures Arabidopsis thaliana
(ATRAPTOR1B, RAPTOR1, RAPTOR1B, AT3G08850) and TOR-repressed lines show significantly higher fluorescence levels from autophagosomes Arabidopsis thaliana
plant autophagy processes involves mega-autophagy pathway
chloroplasts could be selectively degraded via autophagy
tapetal cells of ms33-6038 anthers had more and larger vacuoles from stages 7–8b and showed severe vacuolization; early and excessive autophagy then occurred at stage 9 ms33-6038 anthers Zea mays
(ATPUB9, PUB9, AT3G07360) in root epidermal cells of transgenic -1::GFP- plants localizes to punctate structures in vacuole under starvation Arabidopsis thaliana
pexophagy is one of selective autophagy
repression of the essential chloroplast gene (CLPP1, PCLPP, ATCG00670) activates autophagy Chlamydomonas
concanamycin A (ConcA) blocks vacuolar degradation Arabidopsis thaliana
(APG7, ATAPG7, ATATG7, ATG7, PEUP4, AT5G45900) overexpression stimulates autophagic flux Arabidopsis thaliana
ATG proteins is essential for autophagosome formation
level of autophagy-related proteins (APG5, ATATG5, ATG5, AT5G17290) and (APG8A, ATG8A, AT4G21980) were increased in old leaves of N-limited (ATXDH1, XDH1, AT4G34890) mutant Arabidopsis thaliana
turnover of macromolecules via selective autophagy may contribute to clearance of damaged structures during DILS Hordeum vulgare
autophagosomes are used for bulk degradation of cellular organelles
autophagy provides alternative energy source Arabidopsis thaliana
TAG accumulation was observed in atg mutant lines Arabidopsis thaliana
ConcA treatment increases abundance of RPL37 protein Chlamydomonas
microautophagy initiated soon after senescence induction Hordeum vulgare
autophagy can be induced by nutrient limitation
reduced GUS staining in ark2-1/pub9-1 lines could be result of defective autophagy Arabidopsis thaliana
ATG8 is structural component of autophagosomal membrane Arabidopsis thaliana
autophagy provides alternative nitrogen source Arabidopsis thaliana
coexpression analysis using Genevestigator mRNAseq data suggested that genes are putatively involved in autophagy, protein targeting to vacuole, and vesicle-mediated transport Arabidopsis thaliana
recycled cell contents promote cell survival
(PSS1, AT3G59640) is coregulated with (APG8A, ATG8A, AT4G21980) Arabidopsis thaliana
(ATEXO70B1, EXO70B1, AT5G58430) functions in autophagy Arabidopsis thaliana
lack of (ARK2, AtARK2, RK2, AT1G65800) and (ATPUB9, PUB9, AT3G07360) proteins could block autophagy under phosphate-starved conditions Arabidopsis thaliana
class III (ATVPS34, PI3K, VPS34, AT1G60490) is essential for selective autophagic processes, such as lipophagy Homo sapiens
high starch phenotype has been associated with decreased autophagic flux in PI3K-silenced Arabidopsis Arabidopsis thaliana
loss of chloroplast integrity leads to enhanced autophagy Chlamydomonas reinhardtii
stromules are discussed as structures supporting autophagy of plastid material
reduction in auxin accumulation in lateral roots after 3-MA treatment suggests role for autophagy in controlling auxin accumulation Arabidopsis thaliana
ATG8 lipidation pattern suggests induction of autophagy under normal growth and starvation Chlamydomonas reinhardtii
(ATRAPTOR1B, RAPTOR1, RAPTOR1B, AT3G08850) background shows induction of autophagosomes Arabidopsis thaliana
autophagic degradation eliminates damaged components
recycled cell contents promote cell homeostasis
activation of autophagy and ubiquitin-proteasome pathways suggests FAS inhibition caused substantial damage in the chloroplast that must be contained to prevent cell death Chlamydomonas
15 ATG genes are required for autophagosome formation and autophagy regulation
constitutive autophagy clears away damaged cytosolic material
cerulenin treatment results in detection of lipidated ATG8 Chlamydomonas
mature trichome branch contains putative autophagosomes Arabidopsis thaliana
autophagy is regulated by targets of rapamycin (TOR, AT1G50030) pathway
protein aggregate formation triggers induction of autophagy
(APG5, ATATG5, ATG5, AT5G17290) forms conjugate with ATG12 Arabidopsis thaliana
(ATATG10, ATG10, AT3G07525) mutant was obtained from Richard Vierstra Arabidopsis thaliana
autophagy machinery components including (ATVPS34, PI3K, VPS34, AT1G60490) are required for tolerance to salt stress Arabidopsis thaliana
autophagic bodies colocalizes with markers for lytic compartments Arabidopsis thaliana
(ARK2, AtARK2, RK2, AT1G65800) interaction with (ATPUB9, PUB9, AT3G07360) results in localization of (ATPUB9, PUB9, AT3G07360) to autophagosomes Arabidopsis thaliana
(TOR, AT1G50030) is a repressor of autophagy Chlamydomonas reinhardtii
ATG8 lipidation state is monitored to assess autophagy activation Chlamydomonas reinhardtii
macro-autophagy is related to maintaining normal cellular function
Arabidopsis (ATWRKY33, WRKY33, AT2G38470) is linked to autophagy Arabidopsis thaliana
ATG13, ATG14, and ATG17 proteins are involved in formation of autophagosomal precursor structures Chlamydomonas
stress conditions that cause photooxidative damage of the chloroplast trigger autophagy Chlamydomonas
selective chloroplast degradation via autophagy serves quality control function
whole chloroplasts can be degraded inside lytic vacuoles
nutrient starvation induces transiently autophagy genes Arabidopsis thaliana
C3G naturally inhibit autophagosome breakdown Arabidopsis thaliana
nine genes (five types) encoding proteins that interact with ATG8 protein were upregulated in ms33-6038 anthers at stages 8a–9 Zea mays
vacuolar alkalanization may inhibit normal dissolution of autophagic bodies Arabidopsis thaliana
FL2-OE, CsLPAT2-OE or WT embryos show no obvious autophagy Arabidopsis thaliana
autophagic mechanism participates significantly in capacity of NRSBs to become AVIs Arabidopsis thaliana
autophagy pathway functions in control of 26S proteasome abundance
(ATATG6, AtBECLIN1, ATG6, BECLIN1, VPS30, AT3G61710) requires activity of de-ubiquitinating enzymes for maintenance of steady-state levels Mammalia
ccz1a1b mutant plants shows no autophagic bodies detected after autophagy induction Arabidopsis thaliana
autophagy can also act as cytoprotective mechanism to limit the spread of HR
(ATMC1, AtMCP1b, ATMCPB1, LOL3, MC1, MCP1b, AT1G02170) acts in parallel to autophagy in positively regulating pathogen-triggered HR in young plants Arabidopsis thaliana
NRSB could correspond to autophagic bodies Arabidopsis thaliana
AVIs continue to be subjected to autophagic body breakdown Arabidopsis thaliana
ATG5–ATG12 conjugation is essential for formation of sequestering vesicles Arabidopsis thaliana
transcriptional activation of autophagy leads to release and catabolism of amino acids
MeHSP90.9 interacts with MeATG8b Manihot esculenta
MeRAR1 interacts with MeATG12 Manihot esculenta
particular flavonoid/anthocyanin may induce autophagy Arabidopsis thaliana
MeATG12 overexpression promotes formation of autophagosomes Manihot esculenta
autophagy participates in NRSB formation Arabidopsis thaliana
alkaline vacuolar pH would inhibit release of free GFP Arabidopsis thaliana
ESCRT machineries are implicated in early and late steps during autophagic flux
ZmMC1 and ZmMC2 partially co-localized with autophagic marker (APG8A, ATG8A, AT4G21980) Zea mays; Nicotiana benthamiana
prolonged starvation brings about breakdown of proteins in newly formed lysosomes
PexRD54 effector directs autophagic vesicles Phytophthora infestans
atg mutants display lower numbers of Anthocyanic Vacuolar Inclusions (AVIs) Arabidopsis thaliana
tomato HsfA1 induces autophagy Solanum lycopersicum
MeRAR1 promotes monodansylcadaverine (MDC)-stained autophagosomes Manihot esculenta
EXPO (exocyst-positive organelle) is distinct from autophagosomes
MeATG12 promotes monodansylcadaverine (MDC)-stained autophagosomes Manihot esculenta
atg7-1 mutant does not significantly alter number of NRSBs and AVIs Arabidopsis thaliana
treatment of Chlamydomonas reinhardtii cells with rapamycin induces cell structures reminiscent of autophagosomes Chlamydomonas reinhardtii
autophagy is often triggered by ROS
MeATG8b overexpression promotes formation of autophagosomes Manihot esculenta
ATGs (Autophagy-related proteins) are involved in autophagy
29 autophagy-related genes were upregulated in mutant anthers Zea mays
singlet oxygen (1O2) has ability to initiate cellular degradation Arabidopsis thaliana
(TOR, AT1G50030) pathway has not yet established direct connection with autophagy Arabidopsis thaliana
(TOR, AT1G50030) (target of rapamycin) pathway regulates autophagy
concanamycin A is attenuator of autophagic bodies breakdown Arabidopsis thaliana
autophagy is promoted by AuTophaGy-related (ATG) signaling
Golgi apparatus ARM, ARM13 functions in autophagy process Arabidopsis thaliana
autophagy process is initiated by formation of the autophagosome
autophagic proteins are involved in membrane sequestration
network biology algorithms include genomics
systematical modular analysis of the Arabidopsis proteome identified autophagy-related candidate proteins Arabidopsis thaliana
autophagosomes were highly accumulated in cytoplasm of root cells under NH4+ −Suc conditions Arabidopsis thaliana
autophagic flux inhibition is independent of sucrose Arabidopsis thaliana
MCs have been shown to be related with autophagy
endomembrane machineries have functional roles in autophagy pathway plants
Avh195 encodes potential SLiM Phytophthora parasitica
autophagic bodies could coalesce and result in AVIs Arabidopsis thaliana
Atg candidates in ARM13 are functionally similar to core ATG proteins Arabidopsis thaliana
atg mutants interfere with autophagic process Arabidopsis thaliana
loss of ZmMs33 function caused early and excessive autophagy Zea mays
upregulation of 29 autophagy-related genes in mutant anthers consistent with severe autophagy phenotypes observed in mutant tapetal cells since stage 9 Zea mays
MeHSP90.9 interacts with MeATG8c Manihot esculenta
MeATG8b promotes monodansylcadaverine (MDC)-stained autophagosomes Manihot esculenta
(ATATG6, AtBECLIN1, ATG6, BECLIN1, VPS30, AT3G61710) is essential for autophagosome formation Arabidopsis thaliana
autophagic process is upregulated in response to wide variety of abiotic and biotic stresses
NH4+ -fed plants shows sharply reduced number of autophagic bodies compared to NO3− -fed plants Arabidopsis thaliana
ATG8 and (ATEXO70E2, EXO70E2, AT5G61010) accumulate in vacuole upon autophagy induction
P. infestans effector PexRD54 outcompetes binding of host cargo receptor Joka2 Phytophthora infestans
increase in number of punctate structures after phosphate starvation indicates occurrence of basal autophagy under normal conditions, elevated on starvation Arabidopsis thaliana
phosphorylation of (ATPUB9, PUB9, AT3G07360) by (ARK2, AtARK2, RK2, AT1G65800) resulted in formation of punctate structures in 40% of cells Arabidopsis thaliana
autophagy is discussed in context of adaptive response to prolonged darkness Haberlea rhodopensis
amiR_TOR lines show clear increase in autophagosomes Arabidopsis thaliana
endoplasmic reticulum stress activates autophagy Chlamydomonas reinhardtii
microautophagy involves tonoplast invagination
MeATG8e overexpression promotes formation of autophagosomes Manihot esculenta
silencing of mcII-Pa dramatically decreases number of autophagosomes Picea abies
autophagy in plants is important during growth under nitrogen-limiting conditions Arabidopsis thaliana
autophagy controls heat shock protein 21 (HSP21, AT4G27670) abundance during thermomemory phase
autophagic bodies are broken down by vacuolar resident hydrolases Arabidopsis thaliana
autophagy-related protein (ATATG6, AtBECLIN1, ATG6, BECLIN1, VPS30, AT3G61710) is a subunit of core autophagic machinery
MeRAR1-silenced cassava plants exhibit significantly less autophagosomes Manihot esculenta
known Atg proteins is used to identify autophagy-related modules (ARMs) Arabidopsis thaliana
autophagy-related (Atg) proteins and regulators interact with lipid components and other membrane trafficking-related complexes
information on the global organization of the plant autophagy system is relatively little
autophagy degrades cytoplasmic components
hydrolytic enzymes participate in autophagic body breakdown Arabidopsis thaliana
candidates with annotated functions in different abiotic stresses or development stages in ARMs raise hypothesis that distinct machinery may function in autophagosome biogenesis upon environmental changes Arabidopsis thaliana
autophagy suggesting a dual role, acting as either pro-death or pro-survival process
earlier evidence suggests causal relationship between stromule and (AtECB1, ECB1, MRL7, PDE333, RCB, SVR4, AT4G28590) formation
MeSGT1 promotes monodansylcadaverine (MDC)-stained autophagosomes Manihot esculenta
(AGD1, VAL1, AT5G61980) and (ATSEC14, SEC14, AT4G39180) provides evidence for cross-talk between intracellular pathways and autophagy Arabidopsis thaliana
autophagic bodies are degraded in vacuolar lumen Arabidopsis thaliana
protein breakdown in lysosomes regenerates amino acid pools
(AtHsp90-7, AtHsp90.7, HSP90, HSP90.7, SHD, AT4G24190) and (ATFKBP62, FKBP62, ROF1, AT3G25230) protein stability during recovery phase are regulated through selective autophagic degradation mediated by (AtNBR1, NBR1, AT4G24690)
autophagosome biogenesis is driven by autophagy-related (Atg) proteins and regulators
proteins in ARM13 significantly overrepresented in pathway of Autophagy-other and Gene Ontology biological processes Arabidopsis thaliana
(ATATG6, AtBECLIN1, ATG6, BECLIN1, VPS30, AT3G61710) shows colocalization with Atg8 as punctate structure Arabidopsis thaliana
lack of prediction tools for extracting sequence and molecular features of Atg proteins is a main reason for limited development of algorithms for autophagy prediction
topological network approach should be a potentially successful strategy to identify new Atg proteins
autophagic proteins are involved in initiation
computational framework has potential to facilitate identification of novel autophagy proteins
increased stromule formation in leaf pavement cells and other non-mesophyll cells of (GLES1, TGD5, AT1G27695) suba1 is associated with autophagy (particularly the (AtECB1, ECB1, MRL7, PDE333, RCB, SVR4, AT4G28590) pathway) Arabidopsis thaliana
increased stromule formation in leaf pavement cells and other non-mesophyll cells of (GLES1, TGD5, AT1G27695) suba1 currently has no evidence linking to autophagy in these non-mesophyll cells of the (GLES1, TGD5, AT1G27695) suba1 mutants Arabidopsis thaliana
potato ATG8C-Like has similarities to Arabidopsis (ATG8C, AT1G62040) Solanum tuberosum; Arabidopsis thaliana
autophagosome membrane origin remains elusive
autophagic degradation of heat shock proteins (HSPs) could participate in reversion of cellular proteome to pre-stress state
(AKIN10, KIN10, SnRK1, SnRK1α1, SNRK1.1, AT3G01090) may induce early and excessive autophagy Zea mays
autophagic pathway can be enhanced by cellular stresses
stromal CFP-containing particles resembled Rubisco-containing bodies (RCBs) Arabidopsis thaliana
autophagy adaptors are responsible for selective cargo sorting
DRWIRL motif region is classified as ligand binding motif (LIG_LIR_Gen_1) Phytophthora parasitica
computational framework has facilitated the identification and characterization of plant-specific autophagy-related proteins Arabidopsis thaliana
(AGD1, VAL1, AT5G61980) and (ATSEC14, SEC14, AT4G39180) localization suggest localization at autophagic structures Arabidopsis thaliana
inhibition of macroautophagy and induction of microautophagy appear to be relevant physiological mechanism underlying the ammonium (NH4+) sensitivity response Arabidopsis thaliana
Rubisco-containing bodies (RCBs) are eventually delivered to the vacuole via macroautophagic pathway Arabidopsis thaliana
KCl-treated cells exhibit degradation of organelles by autophagy Micrasterias denticulata
autophagy core machinery and regulators play central roles in autophagy process
connection between micro- and macroautophagy has not yet been fully elucidated
PexRD54 perturbs host-selective autophagy Solanum tuberosum; Solanum lycopersicum
ubiquitination system and autophagy increasing understanding on relationship between higher plants Arabidopsis thaliana
RCB-mediated autophagy is activated under energy-starved conditions
P. infestans effector PexRD54 may manipulate direction of ATG8-labelled autophagosomes to plant-host interface Phytophthora infestans
Phytophthora parasitica Avh195 effector facilitates association with host autophagy-related protein 8 (ATG8) Phytophthora parasitica
motif Asp-Trp-Glu-Ile-Val (DWEIV) is classified as ligand binding SLiM (LIG_LIR_Gen_1) Phytophthora infestans
ARM8 and ARM12 function as response to starvation stimulus
autophagic process is upregulated during leaf senescence
alkaline vacuolar pH would inhibit activity of proteases and hydrolases responsible for GFP-ATG8a degradation Arabidopsis thaliana
suba1 vacuole-enclosed lipid droplets surrounded by cytosolic constituents indicate lipid droplets present within vacuolar lumen due to autophagy Arabidopsis thaliana
P. infestans effector PexRD54 stimulates autophagic flux Phytophthora infestans
Phytophthora parasitica RxLR effector Avh195 interacts with ATG8 Phytophthora parasitica
MeSGT1-silenced cassava plants exhibit significantly less autophagosomes Manihot esculenta
integration of autophagy-related genes into modules offers opportunities to study PPIs with functional and machinery significance Arabidopsis thaliana
VPS41-coated VAPVs fuse with tonoplast independently of HOPS
autophagy induction causes (ATVAM2, ATVPS41, VAM2, VPS41, ZIP2, AT1G08190) condensates to associate with membranes Arabidopsis
aggregated molecules of Z-variant of human α-1 proteinase inhibitor reach vacuole
(APG5, ATATG5, ATG5, AT5G17290) /GFP-ATG8a plants shows no differences in GFP-ATG8a degradation among different growth conditions Arabidopsis thaliana
conventional membrane trafficking machinery is involved in macroautophagy pathway in plants
vacuolar cell death is associated with enhanced autophagy Picea abies
formation of ATG8-marked autophagosome eliminates molecules implicated in defense Phytophthora infestans
multiple pathways for chloroplast degradation by autophagy have been characterized
systems-level algorithm discovered previously uncharacterized novel candidates for Atg proteins or regulators
ARM1, ARM2, ARM3 and ARM4 are involved in process utilizing autophagic mechanism
(AGD1, VAL1, AT5G61980) and (ATSEC14, SEC14, AT4G39180) colocalization with (APG8H, ATG8I, AT3G15580) suggest functional diversity for plant Atg8 superfamily Arabidopsis thaliana
ARM8 function in response to starvation stimulus Arabidopsis thaliana
subversion of host autophagy by plant bacterial leaf pathogen involves promoting degradation of key autophagy component
autophagosomes fuse with vacuole for degradation
findings provided strong hints for cross-talk between autophagy pathway and other cellular processes
(RAB, RBE, AT5G06070) small GTPases are implicated in early and late steps during autophagic flux
CCZ1-MON1 module participates in late events of the macroautophagic process
yeast AUTOPHAGY (ATG) protein system has orthologs in Arabidopsis Arabidopsis thaliana
Arabidopsis ATG genes confirmed presence of autophagy in plants Arabidopsis thaliana
vanadate has been shown to inhibit autophagy in yeast
E3 ligase activity of XopL is important to suppress host autophagic activity
MeATG8e promotes monodansylcadaverine (MDC)-stained autophagosomes Manihot esculenta
autophagic proteins are involved in vacuolar fusion for degradation
ubiquitin-proteasome system and autophagy form interconnected quality control network to achieve cellular quality control Mammalia
late steps of macroautophagy were hypothesized to be impaired under NH4+ toxicity conditions Arabidopsis thaliana
autophagy in plants is important during senescence Arabidopsis thaliana
MeHSP90.9 overexpression promotes formation of autophagosomes Manihot esculenta
ccz1a1b mutant plants expressing GFP-ATG8a shows accumulation of autophagosomes in root cells even in control conditions Arabidopsis thaliana
ZmMC1 and ZmMC2 were co-localized with AtATG8a at the punctate dots Zea mays
plant viruses leverage selective autophagy
autophagy-defective (ATG4, CHLG, G4, PDE325, AT3G51820) mutants do not display Rubisco-containing bodies (RCBs) Arabidopsis thaliana
autophagy pathway is suggested to play a role in chloroplast degradation
(ATSEC14, SEC14, AT4G39180) experimentally validated as candidate in regulation of autophagy Arabidopsis thaliana
putative lipid droplets (or oil bodies) appeared to be engulfed by vacuole Arabidopsis thaliana
ATG8 (autophagy-related protein 8) labels autophagosomes
T-DNA (APG7, ATAPG7, ATATG7, ATG7, PEUP4, AT5G45900) allele in SALK_057605 can be used to test role of autophagy in the lesion-mimic phenotype of (AT-SYR1, ATSYP121, ATSYR1, PEN1, SYP121, SYR1, AT3G11820) (ATSYP122, SYP122, AT3G52400) Arabidopsis thaliana
lts1-204 mutant cytoplasm contained autophagous vacuoles containing dark material
(ATVAM2, ATVPS41, VAM2, VPS41, ZIP2, AT1G08190) relocates from cytoplasmic condensates to phagophores
absence of large number of proteins involved in PSI and PSII could be related to autophagy process Solanum lycopersicum
microautophagy involves invagination of vacuolar membrane
low selectivity of proteolysis in autophagy results in chlorophagy pathway non-selectively transported all photosystem proteins from the chloroplasts to the vacuole
γ-secretase subunits could be somehow connected to autophagy Arabidopsis thaliana
(ATATG18F, ATG18F, G18F, AT5G54730) was upregulated in Arabidopsis seedlings exposed to nitrogen starvation Arabidopsis thaliana
large numbers of membrane-containing vacuoles in lts1-204 may arise as consequence of attempt to recycle thylakoid components Chlamydomonas reinhardtii
MeRAR1 interacts with MeATG8c Manihot esculenta
protein subcellular localization is used to identify autophagy-related modules (ARMs) Arabidopsis thaliana
network biology algorithms including genomics, transcriptomics, proteomics and lipidomics contribute to enhancing understanding of autophagy
autophagy-related candidate proteins closely interact with core autophagic machinery Arabidopsis thaliana
ARM1 function in process utilizing autophagic mechanism Arabidopsis thaliana
autophagy is enhanced in response to nitrogen deficiency
CCZ1-MON1 complex has conserved role in macroautophagic flux in Arabidopsis Arabidopsis thaliana
(ATVAM2, ATVPS41, VAM2, VPS41, ZIP2, AT1G08190) mediates VAPV fusion with the tonoplast Arabidopsis
Rubisco vesicular bodies (RVBs) might be formed as part of autophagasitic process
control seedlings expressing free GFP showed neither GFP-fluorescing bodies in vicinity of root vascular system Arabidopsis thaliana
mutant alleles of (ATATG3, ATG3, AT5G61500) (SALK_031693) and (ATATG6, AtBECLIN1, ATG6, BECLIN1, VPS30, AT3G61710) (SALK_051168) were introduced into syp121–1 syp122–1 Arabidopsis thaliana
GFP–AtAtg8-containing structures in root vascular vicinity are distinct in size and dynamic movement from GFP–AtAtg8-containing autophagosome-resembling structures in root epidermis Arabidopsis thaliana
GFP–AtAtg8f-HA expression under 35S promoter improves growth of plants under light-limiting conditions
autophagic/vacuolar-like cell death may display nuclear degradation
autophagy has role in housekeeping functions related to oxidative stress vascular plants
early steps of the autophagic flux were not remarkably impaired by NH4+ toxicity Arabidopsis thaliana
(AtNBR1, NBR1, AT4G24690) (Next-to-BRCA1) acts as receptor for selective autophagy of ribosomes (ribophagy)
potential SLiM in Avh195 is crucial in manipulating host autophagy Phytophthora parasitica
autophagy genes (ATGs) have been identified in a variety of organisms
lts1-204 mutant strain accumulated cytoplasmic compartments that appeared to be autophagous vacuoles filled with membranous material Chlamydomonas reinhardtii
autophagy often occurs in cells, tissues, or organs directly dependent on an external source of assimilates
module clustering and functional analysis led to selection of four protein members in ARM13 Arabidopsis thaliana
Two proteins in ARM13 are known Atg proteins Arabidopsis thaliana
autophagy pathway is suggested to play a role in nutrient remobilization
(ATATG18F, ATG18F, G18F, AT5G54730) was upregulated in Arabidopsis seedlings exposed to sucrose Arabidopsis thaliana
knockout mutants in autophagy-associated genes render plants more sensitive to sugar starvation
stress-induced non-specific autophagasitic pathways of protein degradation have been described in plants
atg knockout mutants are more sensitive to short-day photoperiod Arabidopsis thaliana
organelles are degenerated and enclosed by membraneous structures probably derived from the ER
macroautophagy is enhanced under nitrogen starvation and salt stress Arabidopsis thaliana
p35S::mCherry-YFP-NBR1 transgenic line expresses mCherry-YFP-NBR1 fusion protein Arabidopsis thaliana
ATG8 (autophagy-related protein 8) functions in biogenesis of starvation-induced autophagosomes
limiting carbon levels stimulate autophagy
actin polymerization could be involved in trafficking of autophagosomes to lytic compartment
Arabidopsis (GRL, LPL3, NAP1, NAPP, AT2G35110) mutant is defective in autophagy as a result is more susceptible to Arabidopsis thaliana
increased autophagy marker levels and lipidated ATG8 is characteristic of mutants defective in autophagy Arabidopsis thaliana
limiting nitrogen levels stimulate autophagy
cytokinin-induced GFP–AtAtg8f-containing structures near vascular system may contain specific proteins targeted for degradation by autophagy
ATG8 proteins are incorporated into autophagosome-resembling structures inside vacuoles
autophagy is indicated by enclosure of organelles by ER-derived double membranes Micrasterias denticulata
constitutive autophagy machinery cross-reacts with novel cellular processes
autophagic/vacuolar-like cell death is characterized by absence of leakage of the intracellular content
autophagy has been known for some time to be important for nutrient remobilization during leaf senescence vascular plants
macroautophagy pathway does not function in (APG5, ATATG5, ATG5, AT5G17290) leaves
mutants in some genes involved in autophagy displayed similar phenotypes to those described in (ATVTI12, VTI12, VTI1B, AT1G26670) and (ATPS1, PS1, AT1G34355) (PS2, AT2G29900) Arabidopsis thaliana
autophagy occurs in response to nutrient starvation
yeast (AtCCME, ATG1, G1, AT3G51790) is essential for cytosol to vacuole pathway and autophagy
prolonged salt stress (24 h) leads to degradation of organelles by autophagy Micrasterias denticulata
autophagy-defective (APG5, ATATG5, ATG5, AT5G17290) mutants do not display Rubisco-containing bodies (RCBs) Arabidopsis thaliana
absence of Rubisco-containing bodies (RCBs) in (ATG4, CHLG, G4, PDE325, AT3G51820) and (APG5, ATATG5, ATG5, AT5G17290) mutants indicates direct involvement of macroautophagy in degradation of Rubisco during leaf senescence Arabidopsis thaliana
(ATATG18F, ATG18F, G18F, AT5G54730) was highly upregulated in senescent SN leaves Hordeum vulgare
autophagosomes sequester cytoplasmic constituents
autophagic trafficking facilitates selective clearance of toxic or redundant structures
cell culture of sycamore shows autophagy Acer pseudoplatanus
(APG7, ATAPG7, ATATG7, ATG7, PEUP4, AT5G45900) is non-redundant gene Arabidopsis thaliana
ATG8 at later stage is recruited to phagophore
(BZR1, AT1G75080) degradation mechanism involves autophagy
NBR1-labeled punctae increase after ConA treatment in wild type Arabidopsis thaliana
autophagic receptors may bind K63-Ub chains Arabidopsis thaliana
ATG8 is central protein of autophagy
tobacco (Nicotiana tabacum) Atg8 is suggested to be involved in transport of protein aggregates containing cytochrome b5 to the vacuole Nicotiana tabacum
interactions between different organelles and lytic compartments demonstrated in Micrasterias Micrasterias
salt stress (200 mM KCl) results in double membrane autophagosomes Micrasterias
salt stress (200 mM NaCl) results in autophagy by enclosure of organelles Micrasterias
ER surrounding organelles leads to double membrane enclosures of organelles Micrasterias
eukaryotes contain autophagy-associated Atg8 proteins
autophagy-associated Atg8 proteins have multiple functions associated with cancer
NaCl-treated cells exhibit degradation of organelles by autophagy Micrasterias denticulata
transcriptional factor (RPH1, AT2G48070) regulates nonselective autophagy by targeting promoter region of (APG9, ATAPG9, ATG9, AT2G31260)
transcriptional factor Pho23 regulates nonselective autophagy by targeting promoter region of ATG14
LC3 and Atg8 can be used as reliable marker for detecting the initiation and progression of autophagy
proportion of free GFP in Δ Moemc5 and Δ Moemc2 was significantly lower than proportion of free GFP in P131 after starvation treatment Magnaporthe oryzae
yeast retromer complex is essential for autophagosome formation via regulation of yeast (APG9, ATAPG9, ATG9, AT2G31260) trafficking Saccharomyces cerevisiae
21 EXO70 proteins possess ATG8-interacting motif Arabidopsis thaliana
Botrytis-infected wild-type plants showed induced autophagosome formation detectable in lesion areas Arabidopsis thaliana
NAP1-GFP-labeled autophagosomes form when plants grown in medium containing high concentrations of NaCl (160 mM) Arabidopsis thaliana
autophagosomes are internalized and become degraded
ConA treatment for 8 h causes accumulation of YFP-ATG8A-positive autophagic bodies in vacuoles Arabidopsis thaliana
Magnaporthe oryzae MoSnt2 regulates autophagy via (TOR, AT1G50030) signaling pathway Magnaporthe oryzae
MpPUB9 colocalization with Arabidopsis EXO70 paralogs within autophagy-related structures suggest that MpPUB9 colocalizes with Arabidopsis EXO70 paralogs within autophagy-related structures, where MpPUB9 is peripherally associated with the cytoplasmic faces of these structures Nicotiana benthamiana
all three liverwort EXO70 isoforms possess ATG8-interacting motif Marchantia polymorpha
autophagy leads to degradation of ubiquitinated plasma membrane proteins in vacuoles
(APG9, ATAPG9, ATG9, AT2G31260) overexpression in mutant Δ Moemc5 can partially restore autophagy level of Δ Moemc5 Magnaporthe oryzae
colocalization of MpPUB9 with Arabidopsis EXO70 paralogs and autophagy marker imply that MpPUB9 may be localized in autophagy-related structures Nicotiana benthamiana
autophagy-mediated recruitment to the vacuole of EXO70 may also be involved in degradation of MpEXO70.1 in intact plant cells Marchantia polymorpha
autophagy enables recycling of macromolecules
merged localization pattern between (ATATG8E, ATG8E, AT2G45170) and MpEXO70.1 was detected Marchantia polymorpha; Arabidopsis thaliana
Rubisco-containing bodies (RCBs) are transported to central vacuole
genes showing highly increased expression during senescence of SN leaves include two genes homologous to the genes encoding autophagy-associated proteins (APG7, ATAPG7, ATATG7, ATG7, PEUP4, AT5G45900) and (ATATG18F, ATG18F, G18F, AT5G54730) in Arabidopsis Hordeum vulgare; Arabidopsis thaliana
clear colocalization of AtPEN-2 with large vesicular structures marked with AtATG8 fluorescence was observed in approximately 80% of cells Arabidopsis thaliana
one gene among the 93 upregulated genes was barley orthologue of the Arabidopsis autophagy-related gene ATG8 Hordeum vulgare; Arabidopsis thaliana
autophagy accomplishes protein degradation Hordeum vulgare
atg knockout mutants are more sensitive to nitrogen starvation Arabidopsis thaliana
RCBs act in chloroplastic autophagy
(AtNBR1, NBR1, AT4G24690) co-immunoprecipitates with K63-Ub chain-specific sensor Arabidopsis thaliana
autophagy-related pathways appeared as predominantly up-regulated categories for protein degradation Hordeum vulgare
KO mutants of SCAR/WAVE and (ARP2, ATARP2, WRM, AT3G27000) /3 complex components is more susceptible to nitrogen starvation Arabidopsis thaliana
ATG8 is commonly used marker for autophagosomes
GFP-UBC35 transport into vacuole is strongly impaired in autophagy-deficient atg7-3 background Arabidopsis thaliana
(ATSRA1, KLK, LPL2, PIR, PIR121, PIRP, SRA1, AT5G18410) mutant shows reduced autophagosome formation Arabidopsis thaliana
ratio of GFP-ATG8 to free GFP is an indicator of autophagic activity
cytoskeleton provides force for membrane deformation
Arabidopsis thaliana atg5-1 mutant is loss-of-function mutant Arabidopsis thaliana
membrane traffic-related proteins involvement in regulation of autophagy is poorly documented in plants
(ATATG18F, ATG18F, G18F, AT5G54730) was reproducibly upregulated specifically in leaves undergoing nitrogen remobilization Hordeum vulgare
exacerbated defects conferred by overexpression of (ATPEX5, EMB2790, PEX5, AT5G56290) in pex6-2 are consistent with possibility that pexophagy is heightened in these mutants when (ATPEX5, EMB2790, PEX5, AT5G56290) is overexpressed Arabidopsis thaliana
leaf-wounding induced autophagy Arabidopsis thaliana
autophagosome-resembling structures are delivered to vacuoles Arabidopsis thaliana
cotyledons grown in vitro on medium without sucrose (−S) did not show autophagy caused by sugar starvation Lupinus luteus; Lupinus albus; Lupinus mutabilis
clear colocalization of AtPEN-2 with large vesicular structures marked with AtATG8 fluorescence indicates that AtPEN-2 is localized to autophagosomes Arabidopsis thaliana
(APG7, ATAPG7, ATATG7, ATG7, PEUP4, AT5G45900) was highly upregulated in senescent SN leaves Hordeum vulgare
membrane trafficking mediates delivery of cellular content to the vacuole/lysosome for degradation
macroautophagy is dynamic catabolic process
reducing (TAP46, AT5G53000) expression by RNAi leads to induction of autophage Arabidopsis thaliana
Autophagy-related protein8 (ATG8) gene did not show differential expression in T411 line Chlamydomonas reinhardtii
metal toxicity activates autophagy Chlamydomonas reinhardtii
autophagy plays a role in nutrient remobilization
(ATRAPTOR1B, RAPTOR1, RAPTOR1B, AT3G08850) mutation leads to induction of autophagy Arabidopsis thaliana
recycled cell contents provide fatty acids
autophagy was prominent at each stage of dark-induced leaf senescence (DILS) Hordeum vulgare
Vacuolar protein sorting15 (AtVPS15, MTV11, VPS15, AT4G29380) is regulatory subunit of (ATVPS34, PI3K, VPS34, AT1G60490) Chlamydomonas reinhardtii
(APG5, ATATG5, ATG5, AT5G17290) overexpression stimulates autophagic flux Arabidopsis thaliana
concanamycin A (ConcA) prevents degradation of ribosomal proteins (RPS6, AT5G46470) and RPL37 Chlamydomonas
activation of autophagy by photooxidative stress has been connected to generation of ROS (reactive oxygen species) Chlamydomonas
autophagy-related proteins regulate autophagy
(GRL, LPL3, NAP1, NAPP, AT2G35110) mutant during N starvation shows formation of autophagosomes prevented autophagosome formation Arabidopsis thaliana
K63 ubiquitination may participate in autophagy Arabidopsis thaliana
ATG8 localizes to similar compartments on ConcA treatment Arabidopsis thaliana
selective autophagic processes such as lipophagy and starch degradation were not activated in T411 mutant Chlamydomonas reinhardtii
stress activates autophagy
oxidative stress activates autophagy Chlamydomonas reinhardtii
advanced dark-induced leaf senescence (DILS) involves enhanced expression of autophagy proteins Hordeum vulgare
(APG9, ATAPG9, ATG9, AT2G31260) is sole membrane-associated autophagy protein Magnaporthe oryzae
human EMC6 is autophagy regulator Homo sapiens
TIR-NB-LRR protein subsequently induces autophagy
(ATEDS1, EDS1, AT3G48090) does not function as general regulator of autophagy pathway Arabidopsis thaliana
eight SNAREs bind ATG8 Saccharomyces cerevisiae
(AtPUX7, PUX7, AT1G14570) contains sole UIM Arabidopsis thaliana
(APG12, ATATG12, ATG12A, AT1G54210) required the LDS for binding to ATG8 Arabidopsis thaliana
ER-localized co-chaperone (ATBAG7, BAG7, AT5G62390) is novel ATG8-interacting protein Arabidopsis thaliana
Ataxin (ATXN)-3 possesses at least two predicted UIMs Homo sapiens
CB-5083 stimulates the autophagic turnover of YFP-CDC48a Arabidopsis thaliana
NAP1-labeled autophagosomes formed either upon oxidative stress induced by H2O2 Nicotiana benthamiana
Arabidopsis plants harboring GFP-ATG8 construct grown in medium without nitrogen form large numbers of autophagosomes Arabidopsis thaliana
impaired autophagy pathway results in plant development and root growth affected more severely Arabidopsis thaliana
constant pressure can induce (GRL, LPL3, NAP1, NAPP, AT2G35110) to localize to autophagosomes Nicotiana benthamiana
GFP:ATG8a autophagy marker is visualized in overlying cells Arabidopsis thaliana
autophagy contributes essential ATP under stress in all known eukaryotes
specific autophagy markers in Chlamydomonas has been fundamental to investigation of autophagy Chlamydomonas reinhardtii
reactive oxygen species (ROS) formation regulates autophagy Chlamydomonas reinhardtii
increased remobilization from older leaves is indicated by enhancement of autophagy-related protein5 (APG5, ATATG5, ATG5, AT5G17290) and (APG8A, ATG8A, AT4G21980) Arabidopsis thaliana
plastid stromules may enable protein degradation by subjecting vesicles of plastid material to autophagy Physcomitrella patens
reducing (TAP46, AT5G53000) expression by virus-induced gene silencing leads to induction of autophage Arabidopsis thaliana
transcript abundance of many autophagy-associated genes decreased significantly T411 line Chlamydomonas reinhardtii
amiR_RAPTOR1B lines show strong increase in autophagosomes Arabidopsis thaliana
amiR_RAPTOR1A lines show rarely detectable MDC-labeled autophagosomes Arabidopsis thaliana
cerulenin treatment decreases levels of (RPS6, AT5G46470) protein Chlamydomonas
NAP1-GFP-labeled puncta are autophagosomes Nicotiana benthamiana
ATG8 is inserted into growing phagophore
(AtNBR1, NBR1, AT4G24690) is canonical autophagy receptor Arabidopsis thaliana
anti-NAP1 identifies autophagosomes Arabidopsis thaliana
hydrogen peroxide triggers formation of autophagosomes
DNP treatment induced autophagosome formation Arabidopsis thaliana
(AtNBR1, NBR1, AT4G24690) co-immunoprecipitation with K63-Ub chain-specific sensor is increased after autophagy activation with dithiothreitol (DTT) Arabidopsis thaliana